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Cytoplasmic Hyaline Globules Present

MedGen UID:: 317567
•Concept ID:: C1707603
•: Finding

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVCytoplasmic Hyaline Globules Present

Histopathology Result
- Morphologic finding
  - Cytoplasmic alteration
    - Cytoplasmic Hyaline Globules Present

Recent clinical studies

Etiology

Fumarate Hydratase-Deficient Leiomyoma of the Uterine Corpus: Comparative Morphologic Analysis of Protein-Deficient Tumors With and Without Pathogenic Germline Fumarate Hydratase Gene Mutations.

Shi W, Liu Y, Aisagbonhi O, Roma AA, Hasteh F, Zare SY, Fadare O
Int J Surg Pathol 2024 Apr;32(2):340-355. Epub 2023 Jun 13 doi: 10.1177/10668969231180285. PMID: 37312573

Juvenile granulosa cell tumor of the ovary: A comprehensive clinicopathologic analysis of 15 cases.

Parikshaa G, Ariba Z, Pranab D, Nalini G, Manish R, Vanita S, Bhavana R, Devi D, Ram S, Prema M, Arvind R, Radhika S
Ann Diagn Pathol 2021 Jun;52:151721. Epub 2021 Feb 10 doi: 10.1016/j.anndiagpath.2021.151721. PMID: 33725665

Cytologic features of upper gynecologic tract adenocarcinomas exhibiting mesonephric-like differentiation.

Kezlarian B, Muller S, Werneck Krauss Silva V, Gonzalez C, Fix DJ, Park KJ, Murali R
Cancer Cytopathol 2019 Aug;127(8):521-528. Epub 2019 Jul 18 doi: 10.1002/cncy.22160. PMID: 31318491 Free PMC Article

Small intestinal gastrointestinal stromal tumor in a young adult woman: a case report and review of the literature.

Manxhuka-Kerliu S, Sahatciu-Meka V, Kerliu I, Juniku-Shkololli A, Kerliu L, Kastrati M, Kotorri V
J Med Case Rep 2014 Sep 28;8:321. doi: 10.1186/1752-1947-8-321. PMID: 25264210 Free PMC Article

Renal oncocytoma with hyaline globules: cytologic diagnosis by guided fine needle aspiration, a case report.

Deshpande A, Munshi M
Indian J Pathol Microbiol 2005 Apr;48(2):230-5. PMID: 16758678

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Diagnosis

Fine needle aspiration cytopathology of eccrine spiradenoma.

Satturwar S, Wakely PE Jr, Lott Limbach A
J Am Soc Cytopathol 2022 Sep-Oct;11(5):274-280. Epub 2022 May 10 doi: 10.1016/j.jasc.2022.05.002. PMID: 35672250

Juvenile granulosa cell tumor of the ovary: A comprehensive clinicopathologic analysis of 15 cases.

Eosinophilic cytoplasmic inclusions in type 2 papillary renal cell carcinoma.

Ungari M, Trombatore M, Ferrero G, Gusolfino MD, Manotti L, Tanzi G, Varotti E, Bertoni R
Pathologica 2019 Dec;111(4):369-374. doi: 10.32074/1591-951X-28-19. PMID: 31965115 Free PMC Article

Solid Pseudopapillary Neoplasm of the Pancreas: A Rare Entity With Unique Features.

Dinarvand P, Lai J
Arch Pathol Lab Med 2017 Jul;141(7):990-995. doi: 10.5858/arpa.2016-0322-RS. PMID: 28661210

Renal oncocytoma with hyaline globules: cytologic diagnosis by guided fine needle aspiration, a case report.

Deshpande A, Munshi M
Indian J Pathol Microbiol 2005 Apr;48(2):230-5. PMID: 16758678

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Therapy

Fumarate Hydratase-Deficient Leiomyoma of the Uterine Corpus: Comparative Morphologic Analysis of Protein-Deficient Tumors With and Without Pathogenic Germline Fumarate Hydratase Gene Mutations.

Shi W, Liu Y, Aisagbonhi O, Roma AA, Hasteh F, Zare SY, Fadare O
Int J Surg Pathol 2024 Apr;32(2):340-355. Epub 2023 Jun 13 doi: 10.1177/10668969231180285. PMID: 37312573

Extragonadal Yolk Sac Tumor Limited to the Myometrium: Report of a Case With Potential Fertility Preservation and Molecular Analysis Suggesting Germ Cell Origin.

Simpson S, Simoni M, Hui P, Taylor HS, Buza N
Int J Gynecol Pathol 2020 May;39(3):247-253. doi: 10.1097/PGP.0000000000000601. PMID: 31033797

Fine needle aspiration cytology of undifferentiated embryonal sarcoma of the liver: a case report.

Sharifah NA, Muhaizan WM, Rahman J, Zulfikar A, Zahari Z
Malays J Pathol 1999 Dec;21(2):105-9. PMID: 11068415

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Prognosis

Small Cell Type Undifferentiated Carcinoma of Gall Bladder with Pas Positive Hyaline Globule Masquerading as Liver Mass: A Case Report and Literature Review.

Gupta RK, Chorasiya VK, Vij V, Wadhawan M, Kumar A, Bansal N
Korean J Gastroenterol 2023 Jan 25;81(1):40-45. doi: 10.4166/kjg.2022.100. PMID: 36695066

Juvenile granulosa cell tumor of the ovary: A comprehensive clinicopathologic analysis of 15 cases.

Cytomorphologic comparison of type 1 and type 2 papillary renal cell carcinoma: A retrospective analysis of 28 cases.

Magers MJ, Perrino CM, Cramer HM, Wu HH
Cancer Cytopathol 2019 Jun;127(6):370-376. Epub 2019 May 15 doi: 10.1002/cncy.22146. PMID: 31091016

Solid Pseudopapillary Neoplasm of the Pancreas: A Rare Entity With Unique Features.

Dinarvand P, Lai J
Arch Pathol Lab Med 2017 Jul;141(7):990-995. doi: 10.5858/arpa.2016-0322-RS. PMID: 28661210

Well-differentiated fetal adenocarcinoma of the lung mimicking adenoid cystic carcinoma on fine needle aspiration: A case report.

Rerkpichaisuth V, Collins JA, Boonyaarunnate T, Ali SZ
Diagn Cytopathol 2016 Nov;44(11):917-920. Epub 2016 Jul 4 doi: 10.1002/dc.23526. PMID: 27374425

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Clinical prediction guides

Endometrial cytological findings for a mesonephric-like endometrial adenocarcinoma: A case report.

Omine H, Ishida K, Sasaki N, Kato H, Nagai T, Ishikawa M, Takaoka M, Noda S, Matsuda H, Mitsuhashi A
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Cytologic features of upper gynecologic tract adenocarcinomas exhibiting mesonephric-like differentiation.

Corpora amylacea in gastrointestinal leiomyomas: a clinical, light microscopic, ultrastructural and immunohistochemical study with comparison to hyaline globules.

Hechtman JF, Gordon RE, McBride RB, Harpaz N
J Clin Pathol 2013 Nov;66(11):951-5. Epub 2013 Jul 6 doi: 10.1136/jclinpath-2013-201701. PMID: 23833049

A human vitelline component in embryonal carcinoma of the testis.

Okamoto T
Acta Pathol Jpn 1986 Jan;36(1):41-8. doi: 10.1111/j.1440-1827.1986.tb01459.x. PMID: 2421530

Hyaline globules and intracellular lumina in a hepatocellular carcinoma.

An T, Ghatak N, Kastner R, Kay S, Lee HM
Am J Clin Pathol 1983 Mar;79(3):392-6. doi: 10.1093/ajcp/79.3.392. PMID: 6299097

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