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Tubule Formation

MedGen UID:
318552
•Concept ID:
C1718420
•
Finding

Definition

The presence of malignant tubular formations which are thought to represent malignant counterparts of the terminal ductal-lobular units of the breast. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTubule Formation

Professional guidelines

PubMed

Unraveling the pharmacodynamic substances and possible mechanism of Trichosanthis Pericarpium in the treatment of coronary heart disease based on plasma pharmacochemistry, network pharmacology and experimental validation.
Zhang XY, Xia KR, Wang YN, Liu P, Shang EX, Liu CY, Liu YP, Qu D, Li WW, Duan JA, Chen Y, Zhang HQ
J Ethnopharmacol 2024 May 10;325:117869. Epub 2024 Feb 9 doi: 10.1016/j.jep.2024.117869. PMID: 38342153
Intraductal tubulopapillary neoplasms of the bile ducts: identity, clinicopathologic characteristics, and differential diagnosis of a distinct entity among intraductal tumors.
Pehlivanoglu B, Adsay V
Hum Pathol 2023 Feb;132:12-19. Epub 2022 Aug 5 doi: 10.1016/j.humpath.2022.07.019. PMID: 35934108
Implementing subtype-specific pre-clinical models of breast cancer to study pre-treatment aspirin effects.
Miller IS, Khan S, Shiels LP, Das S, O' Farrell AC, Connor K, Lafferty A, Moran B, Isella C, Loadman P, Conroy E, Cohrs S, Schibli R, Kerbel RS, Gallagher WM, Marangoni E, Bennett K, O' Connor DP, Dwyer RM, Byrne AT
Cancer Med 2022 Oct;11(20):3820-3836. Epub 2022 Apr 17 doi: 10.1002/cam4.4756. PMID: 35434898Free PMC Article

Recent clinical studies

Etiology

Peri-tumoural spatial distribution of lipid composition and tubule formation in breast cancer.
Chan KS, Cheung SM, Senn N, Husain E, Masannat Y, Heys S, He J
BMC Cancer 2022 Mar 17;22(1):285. doi: 10.1186/s12885-022-09362-1. PMID: 35300617Free PMC Article
Nuclear grade plus proliferation grading system for invasive ductal carcinoma of the breast: validation in a tertiary referral hospital cohort.
Papadimitriou M, Kaptanis S, Polymeropoulos E, Mitsopoulos G, Stogiannis D, Caroni C, Vaiopoulos G, Panayiotides JG, Karakitsos P
Am J Clin Pathol 2015 Dec;144(6):837-43. doi: 10.1309/AJCPVH6FED2ZATUP. PMID: 26572989
Probability of axillary node involvement in patients with tubular carcinoma of the breast.
Papadatos G, Rangan AM, Psarianos T, Ung O, Taylor R, Boyages J
Br J Surg 2001 Jun;88(6):860-4. doi: 10.1046/j.0007-1323.2001.01779.x. PMID: 11412259
Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up.
Elston CW, Ellis IO
Histopathology 1991 Nov;19(5):403-10. doi: 10.1111/j.1365-2559.1991.tb00229.x. PMID: 1757079
Prognostic factors in mammary carcinoma.
Wallgren A, Silfverswärd C, Eklund G
Acta Radiol Ther Phys Biol 1976 Feb;15(1):1-16. doi: 10.3109/02841867609132703. PMID: 1274659

Diagnosis

Cancer-associated fibroblasts facilitate premetastatic niche formation through lncRNA SNHG5-mediated angiogenesis and vascular permeability in breast cancer.
Zeng H, Hou Y, Zhou X, Lang L, Luo H, Sun Y, Wan X, Yuan T, Wang R, Liu Y, Tang R, Cheng S, Xu M, Liu M
Theranostics 2022;12(17):7351-7370. Epub 2022 Oct 17 doi: 10.7150/thno.74753. PMID: 36438499Free PMC Article
Sex-Cord Tumor with Annular Tubules with Unusual Morphology in an Infant with Peutz-Jeghers Syndrome.
Maity P, Das N, Chatterjee U, Basak D
Fetal Pediatr Pathol 2022 Apr;41(2):306-311. Epub 2020 Jul 1 doi: 10.1080/15513815.2020.1786200. PMID: 32609034
FOSL2 promotes VEGF-independent angiogenesis by transcriptionnally activating Wnt5a in breast cancer-associated fibroblasts.
Wan X, Guan S, Hou Y, Qin Y, Zeng H, Yang L, Qiao Y, Liu S, Li Q, Jin T, Qiu Y, Liu M
Theranostics 2021;11(10):4975-4991. Epub 2021 Mar 5 doi: 10.7150/thno.55074. PMID: 33754039Free PMC Article
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Skog J, Würdinger T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO
Nat Cell Biol 2008 Dec;10(12):1470-6. Epub 2008 Nov 16 doi: 10.1038/ncb1800. PMID: 19011622Free PMC Article
Probability of axillary node involvement in patients with tubular carcinoma of the breast.
Papadatos G, Rangan AM, Psarianos T, Ung O, Taylor R, Boyages J
Br J Surg 2001 Jun;88(6):860-4. doi: 10.1046/j.0007-1323.2001.01779.x. PMID: 11412259

Therapy

Peripheral Protein Unfolding Drives Membrane Bending.
Siaw HMH, Raghunath G, Dyer RB
Langmuir 2018 Jul 17;34(28):8400-8407. Epub 2018 Jul 9 doi: 10.1021/acs.langmuir.8b01136. PMID: 29925237Free PMC Article
Ganoderma triterpenes retard renal cyst development by downregulating Ras/MAPK signaling and promoting cell differentiation.
Su L, Liu L, Jia Y, Lei L, Liu J, Zhu S, Zhou H, Chen R, Lu HAJ, Yang B
Kidney Int 2017 Dec;92(6):1404-1418. Epub 2017 Jul 12 doi: 10.1016/j.kint.2017.04.013. PMID: 28709639
The pharmacological bases of the antiangiogenic activity of paclitaxel.
Bocci G, Di Paolo A, Danesi R
Angiogenesis 2013 Jul;16(3):481-92. Epub 2013 Feb 7 doi: 10.1007/s10456-013-9334-0. PMID: 23389639Free PMC Article
Biofunctional materials for directing vascular development.
Saik JE, McHale MK, West JL
Curr Vasc Pharmacol 2012 May;10(3):331-41. doi: 10.2174/157016112799959314. PMID: 22239635
CD40 activation as potential tool in malignant neoplasms.
Ottaiano A, Pisano C, De Chiara A, Ascierto PA, Botti G, Barletta E, Apice G, Gridelli C, Iaffaioli VR
Tumori 2002 Sep-Oct;88(5):361-6. doi: 10.1177/030089160208800502. PMID: 12487551

Prognosis

Dysplasia and Early Carcinoma of the Gallbladder and Bile Ducts: Terminology, Classification, and Significance.
Adsay NV, Basturk O
Gastroenterol Clin North Am 2024 Mar;53(1):85-108. Epub 2023 Nov 17 doi: 10.1016/j.gtc.2023.10.001. PMID: 38280752
Cancer-associated fibroblasts facilitate premetastatic niche formation through lncRNA SNHG5-mediated angiogenesis and vascular permeability in breast cancer.
Zeng H, Hou Y, Zhou X, Lang L, Luo H, Sun Y, Wan X, Yuan T, Wang R, Liu Y, Tang R, Cheng S, Xu M, Liu M
Theranostics 2022;12(17):7351-7370. Epub 2022 Oct 17 doi: 10.7150/thno.74753. PMID: 36438499Free PMC Article
Gastric cancer-derived exosomal miR-519a-3p promotes liver metastasis by inducing intrahepatic M2-like macrophage-mediated angiogenesis.
Qiu S, Xie L, Lu C, Gu C, Xia Y, Lv J, Xuan Z, Fang L, Yang J, Zhang L, Li Z, Wang W, Xu H, Li B, Xu Z
J Exp Clin Cancer Res 2022 Oct 10;41(1):296. doi: 10.1186/s13046-022-02499-8. PMID: 36217165Free PMC Article
ILT3 promotes tumor cell motility and angiogenesis in non-small cell lung cancer.
Li J, Gao A, Zhang F, Wang S, Wang J, Wang J, Han S, Yang Z, Chen X, Fang Y, Jiang G, Sun Y
Cancer Lett 2021 Mar 31;501:263-276. Epub 2020 Nov 3 doi: 10.1016/j.canlet.2020.10.048. PMID: 33152402
Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up.
Elston CW, Ellis IO
Histopathology 1991 Nov;19(5):403-10. doi: 10.1111/j.1365-2559.1991.tb00229.x. PMID: 1757079

Clinical prediction guides

Counteracting Age-Related Netrin-1 Signaling Insufficiency Ameliorates Endothelial Cell Senescence and Angiogenesis Impairment.
Yang Z, Li H, Yan D, Luo P, Guan Y, Luo M, Nie H, Huang Y, Zhang L, Ruan L, Yan J, Zhang C
J Gerontol A Biol Sci Med Sci 2024 Feb 1;79(2) doi: 10.1093/gerona/glad194. PMID: 37561046
BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes.
Perdreau-Dahl H, Lipsett DB, Frisk M, Kermani F, Carlson CR, Brech A, Shen X, Bergan-Dahl A, Hou Y, Tuomainen T, Tavi P, Jones PP, Lunde M, Wasserstrom JA, Laporte J, Ullrich ND, Christensen G, Morth JP, Louch WE
Circ Res 2023 May 26;132(11):e188-e205. Epub 2023 May 4 doi: 10.1161/CIRCRESAHA.122.321732. PMID: 37139790
Gastric cancer-derived exosomal miR-519a-3p promotes liver metastasis by inducing intrahepatic M2-like macrophage-mediated angiogenesis.
Qiu S, Xie L, Lu C, Gu C, Xia Y, Lv J, Xuan Z, Fang L, Yang J, Zhang L, Li Z, Wang W, Xu H, Li B, Xu Z
J Exp Clin Cancer Res 2022 Oct 10;41(1):296. doi: 10.1186/s13046-022-02499-8. PMID: 36217165Free PMC Article
Probability of axillary node involvement in patients with tubular carcinoma of the breast.
Papadatos G, Rangan AM, Psarianos T, Ung O, Taylor R, Boyages J
Br J Surg 2001 Jun;88(6):860-4. doi: 10.1046/j.0007-1323.2001.01779.x. PMID: 11412259
Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up.
Elston CW, Ellis IO
Histopathology 1991 Nov;19(5):403-10. doi: 10.1111/j.1365-2559.1991.tb00229.x. PMID: 1757079

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