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Seasonal affective disorder(SAD)

MedGen UID:
38984
Concept ID:
C0085159
Mental or Behavioral Dysfunction
Synonym: SAD
SNOMED CT: Seasonal affective disorder (247803002); SAD - Seasonal affective disorder (247803002)
 
Monarch Initiative: MONDO:0000694
OMIM®: 608516

Definition

A syndrome characterized by depressions that recur annually at the same time each year, usually during the winter months. Other symptoms include anxiety, irritability, decreased energy, increased appetite (carbohydrate cravings), increased duration of sleep, and weight gain. sad (seasonal affective disorder) can be treated by daily exposure to bright artificial lights (phototherapy), during the season of recurrence. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSeasonal affective disorder

Professional guidelines

PubMed

Swainson J, Reeson M, Malik U, Stefanuk I, Cummins M, Sivapalan S
J Affect Disord 2023 Apr 14;327:270-278. Epub 2023 Feb 3 doi: 10.1016/j.jad.2023.01.094. PMID: 36738997
Nussbaumer-Streit B, Thaler K, Chapman A, Probst T, Winkler D, Sönnichsen A, Gaynes BN, Gartlehner G
Cochrane Database Syst Rev 2021 Mar 4;3(3):CD008591. doi: 10.1002/14651858.CD008591.pub3. PMID: 33661528Free PMC Article
Pjrek E, Friedrich ME, Cambioli L, Dold M, Jäger F, Komorowski A, Lanzenberger R, Kasper S, Winkler D
Psychother Psychosom 2020;89(1):17-24. Epub 2019 Oct 1 doi: 10.1159/000502891. PMID: 31574513

Recent clinical studies

Etiology

Swainson J, Reeson M, Malik U, Stefanuk I, Cummins M, Sivapalan S
J Affect Disord 2023 Apr 14;327:270-278. Epub 2023 Feb 3 doi: 10.1016/j.jad.2023.01.094. PMID: 36738997
Galima SV, Vogel SR, Kowalski AW
Am Fam Physician 2020 Dec 1;102(11):668-672. PMID: 33252911
Pjrek E, Friedrich ME, Cambioli L, Dold M, Jäger F, Komorowski A, Lanzenberger R, Kasper S, Winkler D
Psychother Psychosom 2020;89(1):17-24. Epub 2019 Oct 1 doi: 10.1159/000502891. PMID: 31574513
Kurlansik SL, Ibay AD
Am Fam Physician 2012 Dec 1;86(11):1037-41. PMID: 23198671
Flaskerud JH
Issues Ment Health Nurs 2012 Apr;33(4):266-8. doi: 10.3109/01612840.2011.617028. PMID: 22468593

Diagnosis

Galima SV, Vogel SR, Kowalski AW
Am Fam Physician 2020 Dec 1;102(11):668-672. PMID: 33252911
Tao L, Jiang R, Zhang K, Qian Z, Chen P, Lv Y, Yao Y
Psychiatry Res 2020 Sep;291:113247. Epub 2020 Jun 22 doi: 10.1016/j.psychres.2020.113247. PMID: 32622169
Kurlansik SL, Ibay AD
Am Fam Physician 2012 Dec 1;86(11):1037-41. PMID: 23198671
Danilenko KV, Levitan RD
Handb Clin Neurol 2012;106:279-89. doi: 10.1016/B978-0-444-52002-9.00017-6. PMID: 22608628
Flaskerud JH
Issues Ment Health Nurs 2012 Apr;33(4):266-8. doi: 10.3109/01612840.2011.617028. PMID: 22468593

Therapy

Do A, Li VW, Huang S, Michalak EE, Tam EM, Chakrabarty T, Yatham LN, Lam RW
Can J Psychiatry 2022 Oct;67(10):745-754. Epub 2022 May 6 doi: 10.1177/07067437221097903. PMID: 35522196Free PMC Article
Galima SV, Vogel SR, Kowalski AW
Am Fam Physician 2020 Dec 1;102(11):668-672. PMID: 33252911
Tao L, Jiang R, Zhang K, Qian Z, Chen P, Lv Y, Yao Y
Psychiatry Res 2020 Sep;291:113247. Epub 2020 Jun 22 doi: 10.1016/j.psychres.2020.113247. PMID: 32622169
Barnes J, Anderson LA, Phillipson JD
J Pharm Pharmacol 2001 May;53(5):583-600. doi: 10.1211/0022357011775910. PMID: 11370698
Rosenthal NE, Sack DA, Gillin JC, Lewy AJ, Goodwin FK, Davenport Y, Mueller PS, Newsome DA, Wehr TA
Arch Gen Psychiatry 1984 Jan;41(1):72-80. doi: 10.1001/archpsyc.1984.01790120076010. PMID: 6581756

Prognosis

Borbély AA, Daan S, Wirz-Justice A, Deboer T
J Sleep Res 2016 Apr;25(2):131-43. Epub 2016 Jan 14 doi: 10.1111/jsr.12371. PMID: 26762182
Kurlansik SL, Ibay AD
Am Fam Physician 2012 Dec 1;86(11):1037-41. PMID: 23198671
Magnusson A, Boivin D
Chronobiol Int 2003 Mar;20(2):189-207. doi: 10.1081/cbi-120019310. PMID: 12723880
Jinks J, Melton-Freeman C
Ky Nurse 1995 Jan-Mar;43(1):16-7. PMID: 7731246
Bauer MS
Biol Psychiatry 1992 Jun 15;31(12):1185-9. doi: 10.1016/0006-3223(92)90337-y. PMID: 1391279

Clinical prediction guides

Do A, Li VW, Huang S, Michalak EE, Tam EM, Chakrabarty T, Yatham LN, Lam RW
Can J Psychiatry 2022 Oct;67(10):745-754. Epub 2022 May 6 doi: 10.1177/07067437221097903. PMID: 35522196Free PMC Article
Tao L, Jiang R, Zhang K, Qian Z, Chen P, Lv Y, Yao Y
Psychiatry Res 2020 Sep;291:113247. Epub 2020 Jun 22 doi: 10.1016/j.psychres.2020.113247. PMID: 32622169
Pjrek E, Friedrich ME, Cambioli L, Dold M, Jäger F, Komorowski A, Lanzenberger R, Kasper S, Winkler D
Psychother Psychosom 2020;89(1):17-24. Epub 2019 Oct 1 doi: 10.1159/000502891. PMID: 31574513
Magnusson A, Boivin D
Chronobiol Int 2003 Mar;20(2):189-207. doi: 10.1081/cbi-120019310. PMID: 12723880
Wheatley D
Curr Med Res Opin 1999;15(1):33-7. doi: 10.1185/03007999909115171. PMID: 10216809

Recent systematic reviews

Chen ZW, Zhang XF, Tu ZM
J Affect Disord 2024 Apr 1;350:531-536. Epub 2024 Jan 12 doi: 10.1016/j.jad.2024.01.028. PMID: 38220102
Swainson J, Reeson M, Malik U, Stefanuk I, Cummins M, Sivapalan S
J Affect Disord 2023 Apr 14;327:270-278. Epub 2023 Feb 3 doi: 10.1016/j.jad.2023.01.094. PMID: 36738997
Do A, Li VW, Huang S, Michalak EE, Tam EM, Chakrabarty T, Yatham LN, Lam RW
Can J Psychiatry 2022 Oct;67(10):745-754. Epub 2022 May 6 doi: 10.1177/07067437221097903. PMID: 35522196Free PMC Article
Bertrand L, d'Ortho MP, Reynaud E, Lejoyeux M, Bourgin P, Geoffroy PA
J Affect Disord 2021 Sep 1;292:405-415. Epub 2021 Jun 5 doi: 10.1016/j.jad.2021.05.080. PMID: 34144365
Brouwer A, Nguyen HT, Snoek FJ, van Raalte DH, Beekman ATF, Moll AC, Bremmer MA
Acta Psychiatr Scand 2017 Dec;136(6):534-548. Epub 2017 Sep 10 doi: 10.1111/acps.12785. PMID: 28891192

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