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Decalcification, Pathologic

MedGen UID:
4161
•Concept ID:
C0011085
•
Disease or Syndrome
Synonyms: Decalcification, Pathological; Pathologic Decalcification; Pathological Decalcification

Definition

The loss of calcium salts from bones and teeth. Bacteria may be responsible for this occurrence in teeth. Old age may be a factor contributing to calcium loss, as is the presence of diseases such as rheumatoid arthritis. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecalcification, Pathologic

Professional guidelines

PubMed

Osteoporosis in primary care.
Rudy DR, Falko JM
Ohio State Med J 1985 Mar;81(3):208-12. PMID: 3982779
Preparations to prevent enamel decalcification during orthodontic treatment compared. An in vitro study.
Hughes DO, Hembree JH Jr, Weber FN
Am J Orthod 1979 Apr;75(4):416-20. doi: 10.1016/0002-9416(79)90163-5. PMID: 285617
Management of secondary hyperparathyroidism in renal allograft recipients.
Wilson RE, Hampers CL, Katz AI, Bernstein DS, Wachman A, Merrill JP, Murray JE
Transplant Proc 1969 Mar;1(1):206-8. PMID: 4944219

Recent clinical studies

Etiology

Adhesives for fixed orthodontic brackets.
Mandall NA, Hickman J, Macfarlane TV, Mattick RC, Millett DT, Worthington HV
Cochrane Database Syst Rev 2018 Apr 9;4(4):CD002282. doi: 10.1002/14651858.CD002282.pub2. PMID: 29630138Free PMC Article
Pediatric thyroid nodules: ultrasonographic characteristics and inter-observer variability in prediction of malignancy.
Koltin D, O'Gorman CS, Murphy A, Ngan B, Daneman A, Navarro OM, García C, Atenafu EG, Wasserman JD, Hamilton J, Rachmiel M
J Pediatr Endocrinol Metab 2016 Jul 1;29(7):789-94. doi: 10.1515/jpem-2015-0242. PMID: 27089403
Protrusio acetabuli in osteoporosis and osteomalacia.
Bible MW, Pinals RS, Palmieri GM, Pitcock JA
Clin Exp Rheumatol 1983 Oct-Dec;1(4):323-6. PMID: 6681149
Colonization of the cementum surface of teeth by oral Gram-negative bacteria.
Celesk RA, McCabe RM, London J
Infect Immun 1979 Oct;26(1):15-8. doi: 10.1128/iai.26.1.15-18.1979. PMID: 500200Free PMC Article
Preventing enamel decalcification during orthodontic treatment.
Tillery TJ, Hembree JH Jr, Weber FN
Am J Orthod 1976 Oct;70(4):435-9. doi: 10.1016/0002-9416(76)90116-0. PMID: 788521

Diagnosis

Pediatric thyroid nodules: ultrasonographic characteristics and inter-observer variability in prediction of malignancy.
Koltin D, O'Gorman CS, Murphy A, Ngan B, Daneman A, Navarro OM, García C, Atenafu EG, Wasserman JD, Hamilton J, Rachmiel M
J Pediatr Endocrinol Metab 2016 Jul 1;29(7):789-94. doi: 10.1515/jpem-2015-0242. PMID: 27089403
Temporal bone osteopetrosis.
Wahab Hamed AA, Linthicum FH Jr
Otol Neurotol 2004 Jul;25(4):635. doi: 10.1097/00129492-200407000-00037. PMID: 15241248
Periapical lesions.
Wood NK
Dent Clin North Am 1984 Oct;28(4):725-66. PMID: 6594276
Atlantoaxial dislocations (review).
Pandya SK
Neurol India 1972 Mar;20(1):13-48. PMID: 4264501
Dental enamel: detection of surface changes by ultrasound.
Lees S, Barber FE, Lobene RR
Science 1970 Sep 25;169(3952):1314-6. doi: 10.1126/science.169.3952.1314. PMID: 5454140

Therapy

Adhesives for fixed orthodontic brackets.
Mandall NA, Hickman J, Macfarlane TV, Mattick RC, Millett DT, Worthington HV
Cochrane Database Syst Rev 2018 Apr 9;4(4):CD002282. doi: 10.1002/14651858.CD002282.pub2. PMID: 29630138Free PMC Article
Calcium orthophosphates (CaPO(4)): Occurrence and properties.
Dorozhkin SV
Morphologie 2017 Sep;101(334):125-142. Epub 2017 May 10 doi: 10.1016/j.morpho.2017.03.007. PMID: 28501354
Space flight calcium: implications for astronaut health, spacecraft operations, and Earth.
Smith SM, McCoy T, Gazda D, Morgan JL, Heer M, Zwart SR
Nutrients 2012 Dec 18;4(12):2047-68. doi: 10.3390/nu4122047. PMID: 23250146Free PMC Article
Prevention in orthodontics--a review.
McGuinness NJ
Dent Update 1992 May;19(4):168-70, 172-5. PMID: 1289157
Decalcification under orthodontic bands.
Hirschfield RE, Johnston LE
Angle Orthod 1974 Jul;44(3):218-21. doi: 10.1043/0003-3219(1974)044<0218:DUOB>2.0.CO;2. PMID: 4527732

Prognosis

Risk of Malignancy in Thyroid Nodules with Non-Diagnostic Fine-Needle Aspiration: A Retrospective Cohort Study.
Espinosa De Ycaza AE, Lowe KM, Dean DS, Castro MR, Fatourechi V, Ryder M, Morris JC, Stan MN
Thyroid 2016 Nov;26(11):1598-1604. Epub 2016 Oct 5 doi: 10.1089/thy.2016.0096. PMID: 27549368Free PMC Article
Pediatric thyroid nodules: ultrasonographic characteristics and inter-observer variability in prediction of malignancy.
Koltin D, O'Gorman CS, Murphy A, Ngan B, Daneman A, Navarro OM, García C, Atenafu EG, Wasserman JD, Hamilton J, Rachmiel M
J Pediatr Endocrinol Metab 2016 Jul 1;29(7):789-94. doi: 10.1515/jpem-2015-0242. PMID: 27089403
Bilateral choroidal osteoma: visual acuity at 45-year follow-up.
Hasanreisoglu M, Shields JA, Mashayekhi A, Shields CL
Retin Cases Brief Rep 2015 Summer;9(3):239-41. doi: 10.1097/ICB.0000000000000148. PMID: 25790319
Prevention in orthodontics--a review.
McGuinness NJ
Dent Update 1992 May;19(4):168-70, 172-5. PMID: 1289157
Prolonged weightlessness and calcium loss in man.
Rambaut PC, Johnston RS
Acta Astronaut 1979 Sep;6(9):1113-22. doi: 10.1016/0094-5765(79)90059-6. PMID: 11883480

Clinical prediction guides

Pediatric thyroid nodules: ultrasonographic characteristics and inter-observer variability in prediction of malignancy.
Koltin D, O'Gorman CS, Murphy A, Ngan B, Daneman A, Navarro OM, García C, Atenafu EG, Wasserman JD, Hamilton J, Rachmiel M
J Pediatr Endocrinol Metab 2016 Jul 1;29(7):789-94. doi: 10.1515/jpem-2015-0242. PMID: 27089403
Fine structure of the human cochlear aqueduct: a light and transmission electron microscopic study of decalcified temporal bones.
Toriya R, Arima T, Kuraoka A, Uemura T
Eur Arch Otorhinolaryngol 1994;251 Suppl 1:S38-42. doi: 10.1007/BF02565217. PMID: 11894773
Evaluation of fluoride release from an orthodontic bonding system.
Bishara SE, Swift EJ Jr, Chan DC
Am J Orthod Dentofacial Orthop 1991 Aug;100(2):106-9. doi: 10.1016/S0889-5406(05)81516-1. PMID: 1831002
A light and scanning electron microscopic study of enamel decalcification in children living in a water-fluoridated area.
Thylstrup A, Boyar RM, Holmen L, Bowden GH
J Dent Res 1990 Oct;69(10):1626-33. doi: 10.1177/00220345900690100101. PMID: 2212207
Prolonged weightlessness and calcium loss in man.
Rambaut PC, Johnston RS
Acta Astronaut 1979 Sep;6(9):1113-22. doi: 10.1016/0094-5765(79)90059-6. PMID: 11883480

Recent systematic reviews

Adhesives for fixed orthodontic brackets.
Mandall NA, Hickman J, Macfarlane TV, Mattick RC, Millett DT, Worthington HV
Cochrane Database Syst Rev 2018 Apr 9;4(4):CD002282. doi: 10.1002/14651858.CD002282.pub2. PMID: 29630138Free PMC Article

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