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Eyelid neoplasm

MedGen UID:
41939
•Concept ID:
C0015424
•
Neoplastic Process
Synonyms: Eyelid Neoplasm; Eyelid Neoplasms; Neoplasm, Eyelid; Neoplasms, Eyelid
SNOMED CT: Tumor of eyelid (278697001)
 
Monarch Initiative: MONDO:0002235

Definition

A benign or malignant neoplasm that affects the eyelid. Representative examples include hemangioma, nevus, and carcinoma. [from NCI]

Professional guidelines

PubMed

Sebaceous carcinoma: an updated review of pathogenesis, diagnosis, and treatment options.
Dowell-Esquivel C, Lee R, DiCaprio RC 3rd, Nouri K
Arch Dermatol Res 2023 Dec 19;316(1):55. doi: 10.1007/s00403-023-02747-7. PMID: 38112896
Sebaceous carcinoma: evidence-based clinical practice guidelines.
Owen JL, Kibbi N, Worley B, Kelm RC, Wang JV, Barker CA, Behshad R, Bichakjian CK, Bolotin D, Bordeaux JS, Bradshaw SH, Cartee TV, Chandra S, Cho NL, Choi JN, Council ML, Demirci H, Eisen DB, Esmaeli B, Golda N, Huang CC, Ibrahim SF, Jiang SB, Kim J, Kuzel TM, Lai SY, Lawrence N, Lee EH, Leitenberger JJ, Maher IA, Mann MW, Minkis K, Mittal BB, Nehal KS, Neuhaus IM, Ozog DM, Petersen B, Rotemberg V, Samant S, Samie FH, Servaes S, Shields CL, Shin TM, Sobanko JF, Somani AK, Stebbins WG, Thomas JR, Thomas VD, Tse DT, Waldman AH, Wong MK, Xu YG, Yu SS, Zeitouni NC, Ramsay T, Reynolds KA, Poon E, Alam M
Lancet Oncol 2019 Dec;20(12):e699-e714. doi: 10.1016/S1470-2045(19)30673-4. PMID: 31797796
Kabuki syndrome: international consensus diagnostic criteria.
Adam MP, Banka S, Bjornsson HT, Bodamer O, Chudley AE, Harris J, Kawame H, Lanpher BC, Lindsley AW, Merla G, Miyake N, Okamoto N, Stumpel CT, Niikawa N; Kabuki Syndrome Medical Advisory Board
J Med Genet 2019 Feb;56(2):89-95. Epub 2018 Dec 4 doi: 10.1136/jmedgenet-2018-105625. PMID: 30514738

Recent clinical studies

Etiology

Tarsal Epithelial Cysts: Prevalence, Case Series, and Synthesis of Existing Literature.
Ahmad M, Chen HC, Chang JR, Hodgson N, McDonnell EC, Henderson AD, Siadati S, Eberhart CG, McCulley TJ
Ophthalmic Plast Reconstr Surg 2021 May-Jun 01;37(3):255-261. doi: 10.1097/IOP.0000000000001795. PMID: 32826823
Mucinous eccrine adenocarcinoma of the eyelid: report of 6 cases.
Zhang Q, Wojno TH, Fitch SD, Grossniklaus HE
Can J Ophthalmol 2010 Feb;45(1):76-8. doi: 10.3129/i09-205. PMID: 20130716Free PMC Article

Diagnosis

Collision tumor of sebaceous carcinoma and squamous cell carcinoma of the eyelid: Case report.
Wang JJ, Lee KF, Chen CY
Eur J Ophthalmol 2022 Sep;32(5):NP55-NP59. Epub 2021 May 20 doi: 10.1177/11206721211016303. PMID: 34011202
Tarsal Epithelial Cysts: Prevalence, Case Series, and Synthesis of Existing Literature.
Ahmad M, Chen HC, Chang JR, Hodgson N, McDonnell EC, Henderson AD, Siadati S, Eberhart CG, McCulley TJ
Ophthalmic Plast Reconstr Surg 2021 May-Jun 01;37(3):255-261. doi: 10.1097/IOP.0000000000001795. PMID: 32826823
Eyelid abscess masking underlying sebaceous cell carcinoma.
Bacorn C, Kim E, Lin LK
Orbit 2020 Jun;39(3):212-216. Epub 2019 Sep 18 doi: 10.1080/01676830.2019.1663885. PMID: 31530211
Mucinous eccrine adenocarcinoma of the eyelid: report of 6 cases.
Zhang Q, Wojno TH, Fitch SD, Grossniklaus HE
Can J Ophthalmol 2010 Feb;45(1):76-8. doi: 10.3129/i09-205. PMID: 20130716Free PMC Article
Periocular tumors.
Salasche SJ, Shore JW, Olbricht SM
Dermatol Clin 1992 Oct;10(4):669-85. PMID: 1395151

Therapy

Eyelid abscess masking underlying sebaceous cell carcinoma.
Bacorn C, Kim E, Lin LK
Orbit 2020 Jun;39(3):212-216. Epub 2019 Sep 18 doi: 10.1080/01676830.2019.1663885. PMID: 31530211
"Pseudo-pseudochalazion": giant chalazion mimicking eyelid neoplasm.
Koo L, Hatton MP, Rubin PA
Ophthalmic Plast Reconstr Surg 2005 Sep;21(5):391-2. doi: 10.1097/01.iop.0000176266.14388.6b. PMID: 16234710

Prognosis

Mucinous eccrine adenocarcinoma of the eyelid: report of 6 cases.
Zhang Q, Wojno TH, Fitch SD, Grossniklaus HE
Can J Ophthalmol 2010 Feb;45(1):76-8. doi: 10.3129/i09-205. PMID: 20130716Free PMC Article
Mucoepidermoid/adenosquamous carcinoma of the skin: presentation of two cases.
Johnson DS, Solomon AR, Washington CV
Dermatol Surg 2001 Dec;27(12):1046-8. doi: 10.1046/j.1524-4725.2001.00152.x. PMID: 11849269
An unusual case of metastatic carcinoma to the eyelid.
Graham J, Young SE, Luna M
Am J Ophthalmol 1978 Sep;86(3):400-2. doi: 10.1016/0002-9394(78)90246-5. PMID: 717505

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