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Interstitial myocarditis

MedGen UID:
44554
•Concept ID:
C0027060
•
Disease or Syndrome
Synonyms: Interstitial Myocarditis; interstitial myocarditis
SNOMED CT: Interstitial myocarditis (37925008)
 
Monarch Initiative: MONDO:0004485

Definition

Inflammation of the heart characterized by infiltration of the interstitial tissues by inflammatory cells, histiocytes, and the formation of granulomas. Giant cells are often present. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInterstitial myocarditis

Professional guidelines

PubMed

Diagnosis and treatment of acute interstitial myocarditis in infancy.
VAN CREVELD S, DE GROOT JW, HARTOG HA, LIE SING KIEM
Ann Paediatr 1954 Oct;183(4):193-202. PMID: 13207923

Recent clinical studies

Etiology

Cardiovascular lesions in leptospirosis: an autopsy study.
Chakurkar G, Vaideeswar P, Pandit SP, Divate SA
J Infect 2008 Mar;56(3):197-203. Epub 2008 Feb 11 doi: 10.1016/j.jinf.2007.12.007. PMID: 18262280
Cardiac involvement in the acquired immunodeficiency syndrome: a multicenter clinical-pathological study. Gruppo Italiano per lo Studio Cardiologico dei pazienti affetti da AIDS Investigators.
Barbaro G, Di Lorenzo G, Grisorio B, Barbarini G
AIDS Res Hum Retroviruses 1998 Aug 10;14(12):1071-7. doi: 10.1089/aid.1998.14.1071. PMID: 9718123
Clinical meaning of ventricular ectopic beats in the diagnosis of HIV-related myocarditis: a retrospective analysis of Holter electrocardiographic recordings, echocardiographic parameters, histopathological and virologic findings.
Barbaro G, Di Lorenzo G, Grisorio B, Barbarini G
Cardiologia 1996 Dec;41(12):1199-207. PMID: 9031533
Myocarditis and arrhythmia: a clinico-pathological study of conduction system based on serial section in 65 cases.
Inoue S, Shinohara F, Sakai T, Niitani H, Saito T, Hiromoto J, Otsuka T
Jpn Circ J 1989 Jan;53(1):49-57. doi: 10.1253/jcj.53.49. PMID: 2716170
Lethal complications of typhoid-cholera-vaccination. (Case report and review of the literature).
Mittermayer CH
Beitr Pathol 1976 Jul;158(2):212-24. doi: 10.1016/s0005-8165(76)80197-7. PMID: 985298

Diagnosis

Story telling of myocarditis.
Zanatta A, Carturan E, Rizzo S, Basso C, Thiene G
Int J Cardiol 2019 Nov 1;294:61-64. Epub 2019 Jul 24 doi: 10.1016/j.ijcard.2019.07.046. PMID: 31378380
Fatal myocarditis in adult-onset Still disease with diffuse intravascular coagulation.
Colina M, Govoni M, Trotta F
Rheumatol Int 2009 Sep;29(11):1355-7. Epub 2008 Dec 2 doi: 10.1007/s00296-008-0813-3. PMID: 19048255
Myocarditis and arrhythmia: a clinico-pathological study of conduction system based on serial section in 65 cases.
Inoue S, Shinohara F, Sakai T, Niitani H, Saito T, Hiromoto J, Otsuka T
Jpn Circ J 1989 Jan;53(1):49-57. doi: 10.1253/jcj.53.49. PMID: 2716170
Case for diagnosis: focal interstitial myocarditis.
Sophen IM
Mil Med 1973 May;138(5):283 passim. PMID: 4196455
Diagnosis and treatment of acute interstitial myocarditis in infancy.
VAN CREVELD S, DE GROOT JW, HARTOG HA, LIE SING KIEM
Ann Paediatr 1954 Oct;183(4):193-202. PMID: 13207923

Therapy

Left Ventricular Impaired Relaxation and Interstitial Myocarditis Identified in Sepsis-Associated Cardiac Dysfunction: Use of a Rodent Model.
Sturgess DJ, Morrison S, Haluska B, Gobe GC, Jones MA, Volante S, Venkatesh B
Med Sci Monit 2021 Apr 18;27:e929512. doi: 10.12659/MSM.929512. PMID: 33866323Free PMC Article
Sinus node dysfunction in association with chronic lithium therapy: a case report and review of literature.
Talati SN, Aslam AF, Vasavada B
Am J Ther 2009 May-Jun;16(3):274-8. doi: 10.1097/MJT.0b013e3181822564. PMID: 19352146
Fatal cardiac arrhythmia in a patient with interstitial myocarditis related to chronic arsenic poisoning.
Hall JC, Harruff R
South Med J 1989 Dec;82(12):1557-60. doi: 10.1097/00007611-198912000-00025. PMID: 2595426
Granulomatous myocarditis secondary to cornstarch.
Brynjolfsson G, Eshaghy B, Talano JV, Gunnar RF
Am Heart J 1977 Sep;94(3):353-8. doi: 10.1016/s0002-8703(77)80480-8. PMID: 888768
Lethal complications of typhoid-cholera-vaccination. (Case report and review of the literature).
Mittermayer CH
Beitr Pathol 1976 Jul;158(2):212-24. doi: 10.1016/s0005-8165(76)80197-7. PMID: 985298

Prognosis

Story telling of myocarditis.
Zanatta A, Carturan E, Rizzo S, Basso C, Thiene G
Int J Cardiol 2019 Nov 1;294:61-64. Epub 2019 Jul 24 doi: 10.1016/j.ijcard.2019.07.046. PMID: 31378380
Fatal myocarditis in adult-onset Still disease with diffuse intravascular coagulation.
Colina M, Govoni M, Trotta F
Rheumatol Int 2009 Sep;29(11):1355-7. Epub 2008 Dec 2 doi: 10.1007/s00296-008-0813-3. PMID: 19048255
Cardiovascular lesions in leptospirosis: an autopsy study.
Chakurkar G, Vaideeswar P, Pandit SP, Divate SA
J Infect 2008 Mar;56(3):197-203. Epub 2008 Feb 11 doi: 10.1016/j.jinf.2007.12.007. PMID: 18262280
Cardiac and pulmonary involvement in leptospirosis.
Ramachandran S, Perera MV
Trans R Soc Trop Med Hyg 1977;71(1):56-9. doi: 10.1016/0035-9203(77)90209-7. PMID: 871034
Pathophysiologic studies in human rabies.
Warrell DA, Davidson NM, Pope HM, Bailie WE, Lawrie JH, Ormerod LD, Kertesz A, Lewis P
Am J Med 1976 Feb;60(2):180-90. doi: 10.1016/0002-9343(76)90427-7. PMID: 766622

Clinical prediction guides

Clinical meaning of ventricular ectopic beats in the diagnosis of HIV-related myocarditis: a retrospective analysis of Holter electrocardiographic recordings, echocardiographic parameters, histopathological and virologic findings.
Barbaro G, Di Lorenzo G, Grisorio B, Barbarini G
Cardiologia 1996 Dec;41(12):1199-207. PMID: 9031533
Myocarditis and arrhythmia: a clinico-pathological study of conduction system based on serial section in 65 cases.
Inoue S, Shinohara F, Sakai T, Niitani H, Saito T, Hiromoto J, Otsuka T
Jpn Circ J 1989 Jan;53(1):49-57. doi: 10.1253/jcj.53.49. PMID: 2716170
Cardiovascular involvement in human and experimental leptospirosis: pathologic findings and immunohistochemical detection of leptospiral antigen.
de Brito T, Morais CF, Yasuda PH, Lancellotti CP, Hoshino-Shimizu S, Yamashiro E, Alves VA
Ann Trop Med Parasitol 1987 Jun;81(3):207-14. doi: 10.1080/00034983.1987.11812114. PMID: 3310933
Acute idiopathic interstitial myocarditis: case report with special reference to morphological characteristics of giant cells.
Tanaka M, Ichinohasama R, Kawahara Y, Esaki Y, Hirokawa K, Okishige K, Tanaka Y
J Clin Pathol 1986 Nov;39(11):1209-16. doi: 10.1136/jcp.39.11.1209. PMID: 3793937Free PMC Article
Pathophysiologic studies in human rabies.
Warrell DA, Davidson NM, Pope HM, Bailie WE, Lawrie JH, Ormerod LD, Kertesz A, Lewis P
Am J Med 1976 Feb;60(2):180-90. doi: 10.1016/0002-9343(76)90427-7. PMID: 766622

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