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Abnormal myocardium morphology

MedGen UID:
871271
•Concept ID:
C4025758
•
Anatomical Abnormality
Synonym: Abnormality of the myocardium
 
HPO: HP:0001637

Definition

A structural anomaly of the muscle layer of the heart wall. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal myocardium morphology

Professional guidelines

PubMed

Diagnosis and Treatment of Acute Myocarditis: A Review.
Ammirati E, Moslehi JJ
JAMA 2023 Apr 4;329(13):1098-1113. doi: 10.1001/jama.2023.3371. PMID: 37014337
Presentation, diagnosis, and medical management of heart failure in children: Canadian Cardiovascular Society guidelines.
Kantor PF, Lougheed J, Dancea A, McGillion M, Barbosa N, Chan C, Dillenburg R, Atallah J, Buchholz H, Chant-Gambacort C, Conway J, Gardin L, George K, Greenway S, Human DG, Jeewa A, Price JF, Ross RD, Roche SL, Ryerson L, Soni R, Wilson J, Wong K; Children's Heart Failure Study Group
Can J Cardiol 2013 Dec;29(12):1535-52. doi: 10.1016/j.cjca.2013.08.008. PMID: 24267800
Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the Task Force Criteria.
Marcus FI, McKenna WJ, Sherrill D, Basso C, Bauce B, Bluemke DA, Calkins H, Corrado D, Cox MG, Daubert JP, Fontaine G, Gear K, Hauer R, Nava A, Picard MH, Protonotarios N, Saffitz JE, Sanborn DM, Steinberg JS, Tandri H, Thiene G, Towbin JA, Tsatsopoulou A, Wichter T, Zareba W
Eur Heart J 2010 Apr;31(7):806-14. Epub 2010 Feb 19 doi: 10.1093/eurheartj/ehq025. PMID: 20172912Free PMC Article

Recent clinical studies

Etiology

Cardiomyopathies in children: An overview.
Tsatsopoulou A, Protonotarios I, Xylouri Z, Papagiannis I, Anastasakis A, Germanakis I, Patrianakos A, Nyktari E, Gavras C, Papadopoulos G, Meditskou S, Lazarou E, Miliou A, Lazaros G
Hellenic J Cardiol 2023 Jul-Aug;72:43-56. Epub 2023 Mar 3 doi: 10.1016/j.hjc.2023.02.007. PMID: 36870438
Reevaluation of genetic variants previously associated with arrhythmogenic right ventricular cardiomyopathy integrating population-based cohorts and proteomics data.
Ye JZ, Delmar M, Lundby A, Olesen MS
Clin Genet 2019 Dec;96(6):506-514. Epub 2019 Aug 19 doi: 10.1111/cge.13621. PMID: 31402444
Diabetic Cardiomyopathy: An Update of Mechanisms Contributing to This Clinical Entity.
Jia G, Hill MA, Sowers JR
Circ Res 2018 Feb 16;122(4):624-638. doi: 10.1161/CIRCRESAHA.117.311586. PMID: 29449364Free PMC Article
Arrhythmogenic Cardiomyopathy.
Corrado D, Basso C, Judge DP
Circ Res 2017 Sep 15;121(7):784-802. doi: 10.1161/CIRCRESAHA.117.309345. PMID: 28912183
Cirrhotic cardiomyopathy.
Ruiz-del-Árbol L, Serradilla R
World J Gastroenterol 2015 Nov 7;21(41):11502-21. doi: 10.3748/wjg.v21.i41.11502. PMID: 26556983Free PMC Article

Diagnosis

Cardiomyopathies in children: An overview.
Tsatsopoulou A, Protonotarios I, Xylouri Z, Papagiannis I, Anastasakis A, Germanakis I, Patrianakos A, Nyktari E, Gavras C, Papadopoulos G, Meditskou S, Lazarou E, Miliou A, Lazaros G
Hellenic J Cardiol 2023 Jul-Aug;72:43-56. Epub 2023 Mar 3 doi: 10.1016/j.hjc.2023.02.007. PMID: 36870438
Arrhythmogenic right ventricular cardiomyopathy in dogs.
Cunningham SM, Dos Santos L
J Vet Cardiol 2022 Apr;40:156-169. Epub 2021 Jul 23 doi: 10.1016/j.jvc.2021.07.001. PMID: 34503916
Congenitally corrected transposition.
Wallis GA, Debich-Spicer D, Anderson RH
Orphanet J Rare Dis 2011 May 14;6:22. doi: 10.1186/1750-1172-6-22. PMID: 21569592Free PMC Article
Noncompaction syndrome of the myocardium: pathophysiology and imaging pearls.
Zenooz NA, Zahka KG, Siwik ES, Gilkeson RC
J Thorac Imaging 2010 Nov;25(4):326-32. doi: 10.1097/RTI.0b013e31819ca93e. PMID: 20216462
Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the Task Force Criteria.
Marcus FI, McKenna WJ, Sherrill D, Basso C, Bauce B, Bluemke DA, Calkins H, Corrado D, Cox MG, Daubert JP, Fontaine G, Gear K, Hauer R, Nava A, Picard MH, Protonotarios N, Saffitz JE, Sanborn DM, Steinberg JS, Tandri H, Thiene G, Towbin JA, Tsatsopoulou A, Wichter T, Zareba W
Eur Heart J 2010 Apr;31(7):806-14. Epub 2010 Feb 19 doi: 10.1093/eurheartj/ehq025. PMID: 20172912Free PMC Article

Therapy

Diagnosis and Treatment of Acute Myocarditis: A Review.
Ammirati E, Moslehi JJ
JAMA 2023 Apr 4;329(13):1098-1113. doi: 10.1001/jama.2023.3371. PMID: 37014337
Physiological and pathological roles of protein kinase A in the heart.
Liu Y, Chen J, Fontes SK, Bautista EN, Cheng Z
Cardiovasc Res 2022 Jan 29;118(2):386-398. doi: 10.1093/cvr/cvab008. PMID: 33483740Free PMC Article
The effects of endurance exercise on the heart: panacea or poison?
Parry-Williams G, Sharma S
Nat Rev Cardiol 2020 Jul;17(7):402-412. Epub 2020 Mar 9 doi: 10.1038/s41569-020-0354-3. PMID: 32152528
Arrhythmogenic Cardiomyopathy.
Corrado D, Basso C, Judge DP
Circ Res 2017 Sep 15;121(7):784-802. doi: 10.1161/CIRCRESAHA.117.309345. PMID: 28912183
Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the Task Force Criteria.
Marcus FI, McKenna WJ, Sherrill D, Basso C, Bauce B, Bluemke DA, Calkins H, Corrado D, Cox MG, Daubert JP, Fontaine G, Gear K, Hauer R, Nava A, Picard MH, Protonotarios N, Saffitz JE, Sanborn DM, Steinberg JS, Tandri H, Thiene G, Towbin JA, Tsatsopoulou A, Wichter T, Zareba W
Eur Heart J 2010 Apr;31(7):806-14. Epub 2010 Feb 19 doi: 10.1093/eurheartj/ehq025. PMID: 20172912Free PMC Article

Prognosis

Arrhythmogenic right ventricular cardiomyopathy in dogs.
Cunningham SM, Dos Santos L
J Vet Cardiol 2022 Apr;40:156-169. Epub 2021 Jul 23 doi: 10.1016/j.jvc.2021.07.001. PMID: 34503916
Hypertrabeculation; a phenotype with Heterogeneous etiology.
Adabifirouzjaei F, Igata S, DeMaria AN
Prog Cardiovasc Dis 2021 Sep-Oct;68:60-69. Epub 2021 Jul 13 doi: 10.1016/j.pcad.2021.07.007. PMID: 34265334
Ebstein Anomaly in the Adult Patient.
Fuchs MM, Connolly HM
Cardiol Clin 2020 Aug;38(3):353-363. Epub 2020 Jun 6 doi: 10.1016/j.ccl.2020.04.004. PMID: 32622490
Pediatric Cardiomyopathies.
Lee TM, Hsu DT, Kantor P, Towbin JA, Ware SM, Colan SD, Chung WK, Jefferies JL, Rossano JW, Castleberry CD, Addonizio LJ, Lal AK, Lamour JM, Miller EM, Thrush PT, Czachor JD, Razoky H, Hill A, Lipshultz SE
Circ Res 2017 Sep 15;121(7):855-873. doi: 10.1161/CIRCRESAHA.116.309386. PMID: 28912187Free PMC Article
Cirrhotic cardiomyopathy.
Ruiz-del-Árbol L, Serradilla R
World J Gastroenterol 2015 Nov 7;21(41):11502-21. doi: 10.3748/wjg.v21.i41.11502. PMID: 26556983Free PMC Article

Clinical prediction guides

Hypertrabeculation; a phenotype with Heterogeneous etiology.
Adabifirouzjaei F, Igata S, DeMaria AN
Prog Cardiovasc Dis 2021 Sep-Oct;68:60-69. Epub 2021 Jul 13 doi: 10.1016/j.pcad.2021.07.007. PMID: 34265334
Pulmonary hypertension in children with Down syndrome.
Bush D, Galambos C, Dunbar Ivy D
Pediatr Pulmonol 2021 Mar;56(3):621-629. Epub 2020 Feb 12 doi: 10.1002/ppul.24687. PMID: 32049444
Cardiac imaging in Ebstein anomaly.
Qureshi MY, O'Leary PW, Connolly HM
Trends Cardiovasc Med 2018 Aug;28(6):403-409. Epub 2018 Jan 12 doi: 10.1016/j.tcm.2018.01.002. PMID: 29409687
Arrhythmogenic Cardiomyopathy.
Corrado D, Basso C, Judge DP
Circ Res 2017 Sep 15;121(7):784-802. doi: 10.1161/CIRCRESAHA.117.309345. PMID: 28912183
Mitochondrial dynamics in diabetic cardiomyopathy.
Galloway CA, Yoon Y
Antioxid Redox Signal 2015 Jun 10;22(17):1545-62. Epub 2015 Apr 13 doi: 10.1089/ars.2015.6293. PMID: 25738230Free PMC Article

Recent systematic reviews

Prevalence of abnormal cardiovascular magnetic resonance findings in recovered patients from COVID-19: a systematic review and meta-analysis.
Kim JY, Han K, Suh YJ
J Cardiovasc Magn Reson 2021 Sep 3;23(1):100. doi: 10.1186/s12968-021-00792-7. PMID: 34479603Free PMC Article
Electroanatomic voltage mapping for tissue characterization beyond arrhythmia definition: A systematic review.
Zoppo F, Gagno G, Perazza L, Cocciolo A, Mugnai G, Vaccari D, Calzolari V
Pacing Clin Electrophysiol 2021 Aug;44(8):1432-1448. Epub 2021 Jun 23 doi: 10.1111/pace.14288. PMID: 34096635
Myocardial T1-mapping and extracellular volume in pulmonary arterial hypertension: A systematic review and meta-analysis.
Alabed S, Saunders L, Garg P, Shahin Y, Alandejani F, Rolf A, Puntmann VO, Nagel E, Wild JM, Kiely DG, Swift AJ
Magn Reson Imaging 2021 Jun;79:66-75. Epub 2021 Mar 18 doi: 10.1016/j.mri.2021.03.011. PMID: 33745961
Prevalence of Cardiovascular Complications in Malaria: A Systematic Review and Meta-Analysis.
Holm AE, Gomes LC, Marinho CRF, Silvestre OM, Vestergaard LS, Biering-Sørensen T, Brainin P
Am J Trop Med Hyg 2021 Mar 15;104(5):1643-1650. doi: 10.4269/ajtmh.20-1414. PMID: 33724926Free PMC Article
Myocardial bridges: A meta-analysis.
Roberts W, Charles SM, Ang C, Holda MK, Walocha J, Lachman N, Tubbs RS, Loukas M
Clin Anat 2021 Jul;34(5):685-709. Epub 2021 Feb 22 doi: 10.1002/ca.23697. PMID: 33078444

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