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Secondary Central Nervous System Lymphoma

MedGen UID:
453610
Concept ID:
C2981383
Neoplastic Process

Definition

A non-Hodgkin or Hodgkin lymphoma that has spread to the central nervous system following the initial presentation in another nodal or extranodal site. [from NCI]

Professional guidelines

PubMed

Cwynarski K, Cummin T, Osborne W, Lewis J, Chaganti S, Smith J, Linton K, Greaves P, McKay P, Fox CP; British Society for Haematology (BSH) Committee
Br J Haematol 2023 Jan;200(2):160-169. Epub 2022 Nov 21 doi: 10.1111/bjh.18539. PMID: 36408800
Bobillo S, Khwaja J, Ferreri AJM, Cwynarski K
Haematologica 2023 Mar 1;108(3):673-689. doi: 10.3324/haematol.2022.281457. PMID: 36384246Free PMC Article
Orellana-Noia V, Abousaud A
Curr Treat Options Oncol 2022 Oct;23(10):1443-1456. Epub 2022 Sep 21 doi: 10.1007/s11864-022-01017-4. PMID: 36127571

Recent clinical studies

Etiology

Karschnia P, Arrillaga-Romany IC, Eichler A, Forst DA, Gerstner E, Jordan JT, Ly I, Plotkin SR, Wang N, Martinez-Lage M, Winter SF, Tonn JC, Rejeski K, von Baumgarten L, Cahill DP, Nahed BV, Shankar GM, Abramson JS, Barnes JA, El-Jawahri A, Hochberg EP, Johnson PC, Soumerai JD, Takvorian RW, Chen YB, Frigault MJ, Dietrich J
Neuro Oncol 2023 Dec 8;25(12):2239-2249. doi: 10.1093/neuonc/noad118. PMID: 37402650Free PMC Article
Bobillo S, Khwaja J, Ferreri AJM, Cwynarski K
Haematologica 2023 Mar 1;108(3):673-689. doi: 10.3324/haematol.2022.281457. PMID: 36384246Free PMC Article
Santambrogio E, Nicolosi M, Vassallo F, Castellino A, Novo M, Chiappella A, Vitolo U
Expert Rev Hematol 2019 Sep;12(9):787-796. Epub 2019 Aug 8 doi: 10.1080/17474086.2019.1643232. PMID: 31305170
Tomita N, Kodama F, Kanamori H, Motomura S, Ishigatsubo Y
Int J Hematol 2006 Aug;84(2):128-35. doi: 10.1532/IJH97.06091. PMID: 16926134
Montoto S, Lister TA
Hematol Oncol Clin North Am 2005 Aug;19(4):751-63, viii. doi: 10.1016/j.hoc.2005.05.008. PMID: 16083835

Diagnosis

Bobillo S, Khwaja J, Ferreri AJM, Cwynarski K
Haematologica 2023 Mar 1;108(3):673-689. doi: 10.3324/haematol.2022.281457. PMID: 36384246Free PMC Article
Orellana-Noia V, Abousaud A
Curr Treat Options Oncol 2022 Oct;23(10):1443-1456. Epub 2022 Sep 21 doi: 10.1007/s11864-022-01017-4. PMID: 36127571
Santambrogio E, Nicolosi M, Vassallo F, Castellino A, Novo M, Chiappella A, Vitolo U
Expert Rev Hematol 2019 Sep;12(9):787-796. Epub 2019 Aug 8 doi: 10.1080/17474086.2019.1643232. PMID: 31305170
Tomita N, Kodama F, Kanamori H, Motomura S, Ishigatsubo Y
Int J Hematol 2006 Aug;84(2):128-35. doi: 10.1532/IJH97.06091. PMID: 16926134
Montoto S, Lister TA
Hematol Oncol Clin North Am 2005 Aug;19(4):751-63, viii. doi: 10.1016/j.hoc.2005.05.008. PMID: 16083835

Therapy

Cwynarski K, Cummin T, Osborne W, Lewis J, Chaganti S, Smith J, Linton K, Greaves P, McKay P, Fox CP; British Society for Haematology (BSH) Committee
Br J Haematol 2023 Jan;200(2):160-169. Epub 2022 Nov 21 doi: 10.1111/bjh.18539. PMID: 36408800
Bobillo S, Khwaja J, Ferreri AJM, Cwynarski K
Haematologica 2023 Mar 1;108(3):673-689. doi: 10.3324/haematol.2022.281457. PMID: 36384246Free PMC Article
Cook MR, Dorris CS, Makambi KH, Luo Y, Munshi PN, Donato M, Rowley S, Saad A, Goy A, Dunleavy K, Ali A
Blood Adv 2023 Jan 10;7(1):32-39. doi: 10.1182/bloodadvances.2022008525. PMID: 36260735Free PMC Article
Chukwueke UN, Nayak L
Hematol Oncol Clin North Am 2019 Aug;33(4):597-611. Epub 2019 May 10 doi: 10.1016/j.hoc.2019.03.008. PMID: 31229157
Tomita N, Kodama F, Kanamori H, Motomura S, Ishigatsubo Y
Int J Hematol 2006 Aug;84(2):128-35. doi: 10.1532/IJH97.06091. PMID: 16926134

Prognosis

Orellana-Noia V, Abousaud A
Curr Treat Options Oncol 2022 Oct;23(10):1443-1456. Epub 2022 Sep 21 doi: 10.1007/s11864-022-01017-4. PMID: 36127571
Santambrogio E, Nicolosi M, Vassallo F, Castellino A, Novo M, Chiappella A, Vitolo U
Expert Rev Hematol 2019 Sep;12(9):787-796. Epub 2019 Aug 8 doi: 10.1080/17474086.2019.1643232. PMID: 31305170
Chukwueke UN, Nayak L
Hematol Oncol Clin North Am 2019 Aug;33(4):597-611. Epub 2019 May 10 doi: 10.1016/j.hoc.2019.03.008. PMID: 31229157
Szczepanek D, Wąsik-Szczepanek E, Szymczyk A, Gromek T, Grywalska E, Podhorecka M, Hus M
Neurol Neurochir Pol 2018 May-Jun;52(3):410-414. Epub 2018 Feb 6 doi: 10.1016/j.pjnns.2018.01.007. PMID: 29703403
Tomita N, Kodama F, Kanamori H, Motomura S, Ishigatsubo Y
Int J Hematol 2006 Aug;84(2):128-35. doi: 10.1532/IJH97.06091. PMID: 16926134

Clinical prediction guides

Houillier C, Choquet S
Curr Oncol Rep 2024 Nov;26(11):1521-1529. Epub 2024 Oct 28 doi: 10.1007/s11912-024-01609-3. PMID: 39466477
Karschnia P, Arrillaga-Romany IC, Eichler A, Forst DA, Gerstner E, Jordan JT, Ly I, Plotkin SR, Wang N, Martinez-Lage M, Winter SF, Tonn JC, Rejeski K, von Baumgarten L, Cahill DP, Nahed BV, Shankar GM, Abramson JS, Barnes JA, El-Jawahri A, Hochberg EP, Johnson PC, Soumerai JD, Takvorian RW, Chen YB, Frigault MJ, Dietrich J
Neuro Oncol 2023 Dec 8;25(12):2239-2249. doi: 10.1093/neuonc/noad118. PMID: 37402650Free PMC Article
Cook MR, Dorris CS, Makambi KH, Luo Y, Munshi PN, Donato M, Rowley S, Saad A, Goy A, Dunleavy K, Ali A
Blood Adv 2023 Jan 10;7(1):32-39. doi: 10.1182/bloodadvances.2022008525. PMID: 36260735Free PMC Article
Santambrogio E, Nicolosi M, Vassallo F, Castellino A, Novo M, Chiappella A, Vitolo U
Expert Rev Hematol 2019 Sep;12(9):787-796. Epub 2019 Aug 8 doi: 10.1080/17474086.2019.1643232. PMID: 31305170
Tomita N, Kodama F, Kanamori H, Motomura S, Ishigatsubo Y
Int J Hematol 2006 Aug;84(2):128-35. doi: 10.1532/IJH97.06091. PMID: 16926134

Recent systematic reviews

Asghar N, Masood A, Dhaliwal A, Khurana S, Davis J, Hashmi H, Husnain M
Clin Lymphoma Myeloma Leuk 2023 Jan;23(1):15-21. Epub 2022 Oct 7 doi: 10.1016/j.clml.2022.09.008. PMID: 36328891
Cook MR, Dorris CS, Makambi KH, Luo Y, Munshi PN, Donato M, Rowley S, Saad A, Goy A, Dunleavy K, Ali A
Blood Adv 2023 Jan 10;7(1):32-39. doi: 10.1182/bloodadvances.2022008525. PMID: 36260735Free PMC Article

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