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Gastric Non-Neoplastic Polyp

MedGen UID:
459634
•Concept ID:
C2987408
•
Disease or Syndrome

Definition

A non-neoplastic polyp that arises from the stomach. This category includes hyperplastic polyps and hamartomatous polyps. [from NCI]

Professional guidelines

PubMed

AGA Clinical Practice Update on Nonampullary Duodenal Lesions: Expert Review.
Bourke MJ, Lo SK, Buerlein RCD, Das KK
Gastroenterology 2025 Jan;168(1):169-175. Epub 2024 Nov 16 doi: 10.1053/j.gastro.2024.10.008. PMID: 39545885
Management of Non-neoplastic Gastric Lesions.
Schmocker RK, Lidor AO
Surg Clin North Am 2017 Apr;97(2):387-403. doi: 10.1016/j.suc.2016.11.011. PMID: 28325193

Recent clinical studies

Etiology

Novel classification of gastric polyps: The good, the bad and the ugly.
Costa D, Ramai D, Tringali A
World J Gastroenterol 2024 Aug 21;30(31):3640-3653. doi: 10.3748/wjg.v30.i31.3640. PMID: 39192997Free PMC Article
High interobserver variability and frequent overdiagnosis of dysplasia in fundic gland polyps can be improved by detecting atypia on the surface epithelium and an abrupt transition to non-neoplastic cells.
Orr CE, Beneck D, Jessurun J, Qin L, Tyryshkin K, Yantiss RK, Chen YT
Histopathology 2022 Jan;80(2):314-321. Epub 2021 Oct 13 doi: 10.1111/his.14549. PMID: 34424570
The pathology of gastric and duodenal polyps: current concepts.
Kővári B, Kim BH, Lauwers GY
Histopathology 2021 Jan;78(1):106-124. doi: 10.1111/his.14275. PMID: 33382489
Non-gastric Gastrointestinal Xanthomas: Case Series and Literature Review.
Díaz Del Arco C, Álvarez Sánchez Á, Fernández Aceñero MJ
J Gastrointestin Liver Dis 2016 Sep;25(3):389-94. PMID: 27689205
Gastric mucosal polyps in pernicious anaemia.
Elsborg L, Andersen D, Myhere-Jensen O, Bastrup-Madsen P
Scand J Gastroenterol 1977;12(1):49-52. PMID: 65002

Diagnosis

Novel classification of gastric polyps: The good, the bad and the ugly.
Costa D, Ramai D, Tringali A
World J Gastroenterol 2024 Aug 21;30(31):3640-3653. doi: 10.3748/wjg.v30.i31.3640. PMID: 39192997Free PMC Article
Management of Non-neoplastic Gastric Lesions.
Schmocker RK, Lidor AO
Surg Clin North Am 2017 Apr;97(2):387-403. doi: 10.1016/j.suc.2016.11.011. PMID: 28325193
Non-gastric Gastrointestinal Xanthomas: Case Series and Literature Review.
Díaz Del Arco C, Álvarez Sánchez Á, Fernández Aceñero MJ
J Gastrointestin Liver Dis 2016 Sep;25(3):389-94. PMID: 27689205
Inflammatory Fibroid Polyp of the Stomach Mimics Malignancy on 18F FDG PET/CT Imaging.
Bilgin SS, Bilgin M, Savas R, Erdogan EB
Clin Nucl Med 2016 Sep;41(9):712-3. doi: 10.1097/RLU.0000000000001282. PMID: 27454603
Pathology neoplastic and non-neoplastic.
Graeme-Cook F
Surg Oncol Clin N Am 1996 Jul;5(3):487-512. PMID: 8829315

Therapy

AGA Clinical Practice Update on Nonampullary Duodenal Lesions: Expert Review.
Bourke MJ, Lo SK, Buerlein RCD, Das KK
Gastroenterology 2025 Jan;168(1):169-175. Epub 2024 Nov 16 doi: 10.1053/j.gastro.2024.10.008. PMID: 39545885
Magnification endoscopy with acetic acid enhancement and a narrow-band imaging system for pit pattern diagnosis of colorectal neoplasms.
Shibagaki K, Amano Y, Ishimura N, Yuki T, Taniguchi H, Fujita H, Kobayashi K, Kinoshita Y
J Clin Gastroenterol 2015 Apr;49(4):306-12. doi: 10.1097/MCG.0000000000000148. PMID: 24804989
Celiac disease and gastric hyperplastic polyps: a case series of an uncommon association.
Galvez-Ríos S, Arano-Acua M, Meixueiro-Daza A, Grube-Pagola P, Remes-Troche JM
Eur J Gastroenterol Hepatol 2014 Jul;26(7):807-11. doi: 10.1097/MEG.0000000000000114. PMID: 24901825

Prognosis

Novel classification of gastric polyps: The good, the bad and the ugly.
Costa D, Ramai D, Tringali A
World J Gastroenterol 2024 Aug 21;30(31):3640-3653. doi: 10.3748/wjg.v30.i31.3640. PMID: 39192997Free PMC Article
Mucosal microbial microenvironment in early gastric neoplasia and non-neoplastic gastric disease.
Li F, Zhu H, Tao K, Xia Y, Liu M, Wang Y, Sun Y, Cao T, Chai J, Ni F, Shi B, Xu H
J Gastroenterol Hepatol 2021 Nov;36(11):3092-3101. Epub 2021 Jun 29 doi: 10.1111/jgh.15565. PMID: 34089623
Non-gastric Gastrointestinal Xanthomas: Case Series and Literature Review.
Díaz Del Arco C, Álvarez Sánchez Á, Fernández Aceñero MJ
J Gastrointestin Liver Dis 2016 Sep;25(3):389-94. PMID: 27689205
Pathology neoplastic and non-neoplastic.
Graeme-Cook F
Surg Oncol Clin N Am 1996 Jul;5(3):487-512. PMID: 8829315
Gastric mucosal polyps in pernicious anaemia.
Elsborg L, Andersen D, Myhere-Jensen O, Bastrup-Madsen P
Scand J Gastroenterol 1977;12(1):49-52. PMID: 65002

Clinical prediction guides

Investigation of Clinical, Laboratory, Imaging Findings and Histopathological Features of Patients wıth Gastric Neuroendocrine Cell Hyperplasia.
Çoban B, Bengi G, Derviş Hakim G, Mehtat Ünlü Ş, Solakoğlu Kahraman D, Barlık F, Çapa Kaya G, Soytürk M
Turk J Gastroenterol 2024 Feb;35(2):92-101. doi: 10.5152/tjg.2024.22681. PMID: 38454240Free PMC Article
SP70 is a potential biomarker to identify gastric fundic gland neoplasms.
Luo R, Huang W, Chen L, Liu Y, Xu L, Zhang X, Xu C, Hou Y
World J Surg Oncol 2022 Apr 25;20(1):132. doi: 10.1186/s12957-022-02564-8. PMID: 35468832Free PMC Article
Mucosal microbial microenvironment in early gastric neoplasia and non-neoplastic gastric disease.
Li F, Zhu H, Tao K, Xia Y, Liu M, Wang Y, Sun Y, Cao T, Chai J, Ni F, Shi B, Xu H
J Gastroenterol Hepatol 2021 Nov;36(11):3092-3101. Epub 2021 Jun 29 doi: 10.1111/jgh.15565. PMID: 34089623
Non-gastric Gastrointestinal Xanthomas: Case Series and Literature Review.
Díaz Del Arco C, Álvarez Sánchez Á, Fernández Aceñero MJ
J Gastrointestin Liver Dis 2016 Sep;25(3):389-94. PMID: 27689205
Gastric mucosal polyps in pernicious anaemia.
Elsborg L, Andersen D, Myhere-Jensen O, Bastrup-Madsen P
Scand J Gastroenterol 1977;12(1):49-52. PMID: 65002

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