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Gastric hamartomatous polyp

MedGen UID:
90961
•Concept ID:
C0341225
•
Disease or Syndrome
Synonyms: Gastric Hamartomatous Polyp; gastric hamartomatous polyp; Hamartoma of stomach; Hamartoma of Stomach; hamartoma of stomach; Hamartoma of the Stomach; hamartoma of the stomach; stomach hamartoma (disease)
SNOMED CT: Hamartoma of stomach (235685007)
 
Monarch Initiative: MONDO:0006224

Definition

A non-neoplastic polyp that arises from the stomach and is characterized by the presence of connective tissue stroma overgrowth and cystic formations. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGastric hamartomatous polyp

Professional guidelines

PubMed

Diagnosis and Management of Cancer Risk in the Gastrointestinal Hamartomatous Polyposis Syndromes: Recommendations From the US Multi-Society Task Force on Colorectal Cancer.
Boland CR, Idos GE, Durno C, Giardiello FM, Anderson JC, Burke CA, Dominitz JA, Gross S, Gupta S, Jacobson BC, Patel SG, Shaukat A, Syngal S, Robertson DJ
Gastroenterology 2022 Jun;162(7):2063-2085. Epub 2022 Apr 26 doi: 10.1053/j.gastro.2022.02.021. PMID: 35487791
Diagnosis and management of cancer risk in the gastrointestinal hamartomatous polyposis syndromes: recommendations from the U.S. Multi-Society Task Force on Colorectal Cancer.
Boland CR, Idos GE, Durno C, Giardiello FM, Anderson JC, Burke CA, Dominitz JA, Gross S, Gupta S, Jacobson BC, Patel SG, Shaukat A, Syngal S, Robertson DJ
Gastrointest Endosc 2022 Jun;95(6):1025-1047. Epub 2022 Apr 26 doi: 10.1016/j.gie.2022.02.044. PMID: 35487765
Evaluation and management of gastric epithelial polyps.
Castro R, Pimentel-Nunes P, Dinis-Ribeiro M
Best Pract Res Clin Gastroenterol 2017 Aug;31(4):381-387. Epub 2017 Jun 13 doi: 10.1016/j.bpg.2017.06.001. PMID: 28842047

Recent clinical studies

Etiology

Somatic mutations of LKB1 and beta-catenin genes in gastrointestinal polyps from patients with Peutz-Jeghers syndrome.
Miyaki M, Iijima T, Hosono K, Ishii R, Yasuno M, Mori T, Toi M, Hishima T, Shitara N, Tamura K, Utsunomiya J, Kobayashi N, Kuroki T, Iwama T
Cancer Res 2000 Nov 15;60(22):6311-3. PMID: 11103790

Diagnosis

Carcinoma in situ arising in a gastric hamartomatous polyp in a patient with Peutz-Jeghers syndrome.
Defago MR, Higa AL, Campra JL, Paradelo M, Uehara A, Torres Mazzucchi MH, Videla R
Endoscopy 1996 Feb;28(2):267. doi: 10.1055/s-2007-1005447. PMID: 8739752
Solitary gastric hamartomatous polyp and upper gastrointestinal haemorrhage: an exceptional presentation of an unusual diagnosis.
Erdozain JC, Sánchez-Ruano JJ, San Román AL, Boixeda D, Moreira VF, Plaza AG
Postgrad Med J 1990 Dec;66(782):1084-5. doi: 10.1136/pgmj.66.782.1084. PMID: 2084662Free PMC Article
Gastric hamartomatous polyp without polyposis coli: radiologic diagnosis.
Sato T, Sakai Y, Ishiguro S, Fujita M, Kuriyama K, Narumi Y
Gastrointest Radiol 1988;13(1):19-23. doi: 10.1007/BF01889016. PMID: 3350263
A case of neonatal gastric hamartomatous polyp.
Patiroğlu T, Hasanoğlu A, Patiroğlu TE, Aritaş Y
Turk J Pediatr 1986 Oct-Dec;28(4):249-54. PMID: 3590319

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