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Pontiac fever

MedGen UID:
575661
•Concept ID:
C0343528
•
Disease or Syndrome
Synonyms: Fever, Pontiac; Pontiac Fever
SNOMED CT: Pontiac fever (240447002)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
•Concept ID:
CN307044
•
Finding
Source: Orphanet
clinical entity without genetic inheritance.
See: This record
Not genetically inherited (Orphanet)
 
Monarch Initiative: MONDO:0020487
Orphanet: ORPHA99748

Definition

Pontiac fever (PF) is a mild form of legionellosis (see this term) manifesting with flu-like symptoms such as nausea, myalgia, fever, cough and headache but without pneumonia. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
Follow this link to review classifications for Pontiac fever in Orphanet.

Professional guidelines

PubMed

Population-Based Assessment of Clinical Risk Factors for Legionnaires' Disease.
Cooley LA, Pondo T, Francois Watkins LK, Shah P, Schrag S; Active Bacterial Core Surveillance Program of the Emerging Infections Program Network
Clin Infect Dis 2020 May 23;70(11):2428-2431. doi: 10.1093/cid/ciz771. PMID: 31617567Free PMC Article
Recreational Waterborne Illnesses: Recognition, Treatment, and Prevention.
Perkins A, Trimmier M
Am Fam Physician 2017 May 1;95(9):554-560. PMID: 28671392
Severe Pneumonia Caused by Legionella pneumophila: Differential Diagnosis and Therapeutic Considerations.
Chahin A, Opal SM
Infect Dis Clin North Am 2017 Mar;31(1):111-121. doi: 10.1016/j.idc.2016.10.009. PMID: 28159171Free PMC Article

Recent clinical studies

Etiology

Legionellosis in Poland in 2018-2021.
Czerwiński M, Księżak E, Piekarska K
Przegl Epidemiol 2023;77(2):241-250. doi: 10.32394/pe.77.23. PMID: 37861069
Outbreaks of Legionnaires' Disease and Pontiac Fever 2006-2017.
Hamilton KA, Prussin AJ 2nd, Ahmed W, Haas CN
Curr Environ Health Rep 2018 Jun;5(2):263-271. doi: 10.1007/s40572-018-0201-4. PMID: 29744757
Legionellosis in the occupational setting.
Principe L, Tomao P, Visca P
Environ Res 2017 Jan;152:485-495. Epub 2016 Oct 4 doi: 10.1016/j.envres.2016.09.018. PMID: 27717486
Large outbreak of Legionnaires' disease and Pontiac fever at a military base.
Ambrose J, Hampton LM, Fleming-Dutra KE, Marten C, McClusky C, Perry C, Clemmons NA, McCormic Z, Peik S, Mancuso J, Brown E, Kozak N, Travis T, Lucas C, Fields B, Hicks L, Cersovsky SB
Epidemiol Infect 2014 Nov;142(11):2336-46. doi: 10.1017/S0950268813003440. PMID: 25267405Free PMC Article
An outbreak of travel-associated Legionnaires disease and Pontiac fever: the need for enhanced surveillance of travel-associated legionellosis in the United States.
Benin AL, Benson RF, Arnold KE, Fiore AE, Cook PG, Williams LK, Fields B, Besser RE
J Infect Dis 2002 Jan 15;185(2):237-43. Epub 2001 Dec 18 doi: 10.1086/338060. PMID: 11807698

Diagnosis

Legionellosis in Poland in 2018-2021.
Czerwiński M, Księżak E, Piekarska K
Przegl Epidemiol 2023;77(2):241-250. doi: 10.32394/pe.77.23. PMID: 37861069
European Surveillance of Legionnaires' Disease.
Jong B, Hallström LP
Curr Issues Mol Biol 2021;42:81-96. Epub 2020 Dec 7 doi: 10.21775/cimb.042.081. PMID: 33284133
Atypical Pneumonia: Updates on Legionella, Chlamydophila, and Mycoplasma Pneumonia.
Sharma L, Losier A, Tolbert T, Dela Cruz CS, Marion CR
Clin Chest Med 2017 Mar;38(1):45-58. Epub 2016 Dec 24 doi: 10.1016/j.ccm.2016.11.011. PMID: 28159161Free PMC Article
Large outbreak of Legionnaires' disease and Pontiac fever at a military base.
Ambrose J, Hampton LM, Fleming-Dutra KE, Marten C, McClusky C, Perry C, Clemmons NA, McCormic Z, Peik S, Mancuso J, Brown E, Kozak N, Travis T, Lucas C, Fields B, Hicks L, Cersovsky SB
Epidemiol Infect 2014 Nov;142(11):2336-46. doi: 10.1017/S0950268813003440. PMID: 25267405Free PMC Article
Legionella infections.
Ching WT, Meyer RD
Infect Dis Clin North Am 1987 Sep;1(3):595-614. PMID: 3332887

Therapy

Large outbreak of Legionnaires' disease and Pontiac fever at a military base.
Ambrose J, Hampton LM, Fleming-Dutra KE, Marten C, McClusky C, Perry C, Clemmons NA, McCormic Z, Peik S, Mancuso J, Brown E, Kozak N, Travis T, Lucas C, Fields B, Hicks L, Cersovsky SB
Epidemiol Infect 2014 Nov;142(11):2336-46. doi: 10.1017/S0950268813003440. PMID: 25267405Free PMC Article
Pathogenicity of the family Legionellaceae.
Palusińska-Szysz M, Cendrowska-Pinkosz M
Arch Immunol Ther Exp (Warsz) 2009 Jul-Aug;57(4):279-90. Epub 2009 Jul 4 doi: 10.1007/s00005-009-0035-8. PMID: 19578813
Legionella bacteria in shower aerosols increase the risk of Pontiac fever among older people in retirement homes.
Bauer M, Mathieu L, Deloge-Abarkan M, Remen T, Tossa P, Hartemann P, Zmirou-Navier D
J Epidemiol Community Health 2008 Oct;62(10):913-20. doi: 10.1136/jech.2007.063784. PMID: 18791050
Hot tub legionellosis. Legionnaires' disease and Pontiac fever after a point-source exposure to Legionella pneumophila.
Thomas DL, Mundy LM, Tucker PC
Arch Intern Med 1993 Nov 22;153(22):2597-9. doi: 10.1001/archinte.153.22.2597. PMID: 8239853
Legionellosis: Legionnaires' disease; Pontiac fever.
Cordes LG, Fraser DW
Med Clin North Am 1980 May;64(3):395-416. doi: 10.1016/s0025-7125(16)31600-5. PMID: 6993807

Prognosis

Legionellosis in Poland in 2018-2021.
Czerwiński M, Księżak E, Piekarska K
Przegl Epidemiol 2023;77(2):241-250. doi: 10.32394/pe.77.23. PMID: 37861069
Legionellosis in Poland in 2016.
Stypułkowska-Misiurewicz H, Czerwiński M
Przegl Epidemiol 2018;72(2):143-147. PMID: 30111084
Legionellosis in the occupational setting.
Principe L, Tomao P, Visca P
Environ Res 2017 Jan;152:485-495. Epub 2016 Oct 4 doi: 10.1016/j.envres.2016.09.018. PMID: 27717486
Legionellosis in Poland in 2014.
Stypułkowska-Misiurewicz H, Czerwiński MA
Przegl Epidemiol 2016;70(2):203-207. PMID: 27779835
Large outbreak of Legionnaires' disease and Pontiac fever at a military base.
Ambrose J, Hampton LM, Fleming-Dutra KE, Marten C, McClusky C, Perry C, Clemmons NA, McCormic Z, Peik S, Mancuso J, Brown E, Kozak N, Travis T, Lucas C, Fields B, Hicks L, Cersovsky SB
Epidemiol Infect 2014 Nov;142(11):2336-46. doi: 10.1017/S0950268813003440. PMID: 25267405Free PMC Article

Clinical prediction guides

Legionellosis in Poland in 2018-2021.
Czerwiński M, Księżak E, Piekarska K
Przegl Epidemiol 2023;77(2):241-250. doi: 10.32394/pe.77.23. PMID: 37861069
Legionellosis in the occupational setting.
Principe L, Tomao P, Visca P
Environ Res 2017 Jan;152:485-495. Epub 2016 Oct 4 doi: 10.1016/j.envres.2016.09.018. PMID: 27717486
Colony types and virulence traits of Legionella feeleii determined by exopolysaccharide materials.
Wang C, Saito M, Ogawa M, Yoshida S
FEMS Microbiol Lett 2016 May;363(10) Epub 2016 Apr 15 doi: 10.1093/femsle/fnw098. PMID: 27190244
Legionellosis in Poland in 2013.
Stypułkowska-Misiurewicz H, Czerwiński M
Przegl Epidemiol 2015;69(2):235-7, 357-8. PMID: 26233078
A large, travel-associated outbreak of legionellosis among hotel guests: utility of the urine antigen assay in confirming Pontiac fever.
Burnsed LJ, Hicks LA, Smithee LM, Fields BS, Bradley KK, Pascoe N, Richards SM, Mallonee S, Littrell L, Benson RF, Moore MR; Legionellosis Outbreak Investigation Team
Clin Infect Dis 2007 Jan 15;44(2):222-8. Epub 2006 Dec 8 doi: 10.1086/510387. PMID: 17173221

Recent systematic reviews

Legionellosis Associated with Recreational Waters: A Systematic Review of Cases and Outbreaks in Swimming Pools, Spa Pools, and Similar Environments.
Leoni E, Catalani F, Marini S, Dallolio L
Int J Environ Res Public Health 2018 Jul 30;15(8) doi: 10.3390/ijerph15081612. PMID: 30061526Free PMC Article

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