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Vulvar melanoma

MedGen UID:
66040
Concept ID:
C0241989
Neoplastic Process
Synonyms: Malignant melanoma of vulva; malignant melanoma of vulva; mammalian vulva melanoma; mammalian vulva melanoma (disease); melanoma (disease) of mammalian vulva; Vulvar Melanoma; vulvar melanoma; vulvar melanoma (disease)
SNOMED CT: Malignant melanoma of vulva (254896002)
 
HPO: HP:0030418
Monarch Initiative: MONDO:0002205

Definition

A type of vulvar cancer that originates from melanocytes of the vulva. [from HPO]

Professional guidelines

PubMed

Wohlmuth C, Wohlmuth-Wieser I
Am J Clin Dermatol 2021 Sep;22(5):639-651. Epub 2021 Jun 14 doi: 10.1007/s40257-021-00614-7. PMID: 34125416Free PMC Article
Albert A, Lee A, Allbright R, Vijayakumar S
J Gynecol Oncol 2020 Sep;31(5):e66. doi: 10.3802/jgo.2020.31.e66. PMID: 32808496Free PMC Article
Kumar N, Ray MD, Sharma DN, Pandey R, Lata K, Mishra A, Wankhede D, Saikia J
J Egypt Natl Canc Inst 2020 Jan 14;32(1):4. doi: 10.1186/s43046-019-0015-y. PMID: 32372283

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Vulvar Cancer, 2024

Recent clinical studies

Etiology

Collarino A, Fuoco V, Garganese G, Pasciuto T, de Koster EJ, Florit A, Fragomeni SM, Zagaria L, Fragano A, Martinelli F, Ditto A, Seregni E, Scambia G, Raspagliesi F, Rufini V, Maccauro M
Gynecol Oncol 2023 Mar;170:153-159. Epub 2023 Jan 23 doi: 10.1016/j.ygyno.2023.01.011. PMID: 36696819
Wu Y, Li H, Tan L, Lai Y, Li Z
Hum Pathol 2023 Jan;131:87-97. Epub 2022 Nov 10 doi: 10.1016/j.humpath.2022.11.002. PMID: 36370822
Furlan K, Rohra P, Mir F, Gattuso P
J Cutan Pathol 2020 Oct;47(10):917-922. Epub 2020 Jul 29 doi: 10.1111/cup.13768. PMID: 32511773
Hieta N, Kurki S, Rintala M, Söderlund J, Hietanen S, Orte K
Acta Derm Venereol 2019 Mar 1;99(3):339-340. doi: 10.2340/00015555-3103. PMID: 30521058
Wechter ME, Gruber SB, Haefner HK, Lowe L, Schwartz JL, Reynolds KR, Johnston CM, Johnson TM
J Am Acad Dermatol 2004 Apr;50(4):554-62. doi: 10.1016/j.jaad.2003.07.026. PMID: 15034504

Diagnosis

Pye IM, Saw RPM, Saunderson RB
JAMA Dermatol 2023 Jan 1;159(1):96. doi: 10.1001/jamadermatol.2022.4550. PMID: 36449308
Wohlmuth C, Wohlmuth-Wieser I
Am J Clin Dermatol 2021 Sep;22(5):639-651. Epub 2021 Jun 14 doi: 10.1007/s40257-021-00614-7. PMID: 34125416Free PMC Article
Barquet-Munoz SA, Leitao M, Pérez Montiel MD, Santiago Concha BG
Int J Gynecol Cancer 2019 Jul;29(6):1077-1081. Epub 2019 Jun 13 doi: 10.1136/ijgc-2019-000610. PMID: 31196869Free PMC Article
Brenn T
Arch Pathol Lab Med 2011 Mar;135(3):317-20. doi: 10.5858/2009-0382-RA.1. PMID: 21366454
Panizzon RG
Semin Dermatol 1996 Mar;15(1):67-70. doi: 10.1016/s1085-5629(96)80021-6. PMID: 8723827

Therapy

Zhou H, Zou X, Li H, Chen L, Cheng X
Jpn J Clin Oncol 2020 Dec 16;50(12):1386-1394. doi: 10.1093/jjco/hyaa137. PMID: 32776099
Lopez S, Guerrisi R, Brusadelli C, Bogani G, Ditto A, Raspagliesi F
Minerva Ginecol 2020 Dec;72(6):384-390. Epub 2020 Aug 3 doi: 10.23736/S0026-4784.20.04628-6. PMID: 32744452
Heymann WR
J Am Acad Dermatol 2020 Feb;82(2):301-302. Epub 2019 Nov 8 doi: 10.1016/j.jaad.2019.11.012. PMID: 31712176
Hiratsuka J, Kamitani N, Tanaka R, Yoden E, Tokiya R, Suzuki M, Barth RF, Ono K
Cancer Commun (Lond) 2018 Jun 19;38(1):38. doi: 10.1186/s40880-018-0297-9. PMID: 29914570Free PMC Article
Isenberg A, Paul Shackelford D
Obstet Gynecol Surv 2001 Jun;56(6):377-80. doi: 10.1097/00006254-200106000-00023. PMID: 11466488

Prognosis

Wohlmuth C, Wohlmuth-Wieser I
Am J Clin Dermatol 2021 Sep;22(5):639-651. Epub 2021 Jun 14 doi: 10.1007/s40257-021-00614-7. PMID: 34125416Free PMC Article
Hieta N, Kurki S, Rintala M, Söderlund J, Hietanen S, Orte K
Acta Derm Venereol 2019 Mar 1;99(3):339-340. doi: 10.2340/00015555-3103. PMID: 30521058
Murzaku EC, Penn LA, Hale CS, Pomeranz MK, Polsky D
J Am Acad Dermatol 2014 Dec;71(6):1241-9. Epub 2014 Sep 27 doi: 10.1016/j.jaad.2014.08.019. PMID: 25267379
Isenberg A, Paul Shackelford D
Obstet Gynecol Surv 2001 Jun;56(6):377-80. doi: 10.1097/00006254-200106000-00023. PMID: 11466488
Panizzon RG
Semin Dermatol 1996 Mar;15(1):67-70. doi: 10.1016/s1085-5629(96)80021-6. PMID: 8723827

Clinical prediction guides

Ogata D, Nishio S, Hatta N, Kaji T, Fujii K, Mikami M, Kiyohara Y, Enomoto T
Melanoma Res 2023 Aug 1;33(4):300-308. Epub 2023 May 26 doi: 10.1097/CMR.0000000000000894. PMID: 37162526Free PMC Article
Cook EE, Harrison BT, Hirsch MS
Histopathology 2023 Jul;83(1):104-108. Epub 2023 Mar 27 doi: 10.1111/his.14908. PMID: 36971374
Koeller DR, Schwartz A, DeSimone MS, Rana HQ, Rojas-Rudilla V, Russell-Goldman E, Laga AC, Lindeman NI, Garber JE, Ghazani AA
Cancer Genet 2022 Apr;262-263:102-106. Epub 2022 Feb 15 doi: 10.1016/j.cancergen.2022.02.003. PMID: 35220194
Albert A, Lee A, Allbright R, Vijayakumar S
J Gynecol Oncol 2020 Sep;31(5):e66. doi: 10.3802/jgo.2020.31.e66. PMID: 32808496Free PMC Article
Zhou H, Zou X, Li H, Chen L, Cheng X
Jpn J Clin Oncol 2020 Dec 16;50(12):1386-1394. doi: 10.1093/jjco/hyaa137. PMID: 32776099

Recent systematic reviews

Collarino A, Fuoco V, Garganese G, Pasciuto T, de Koster EJ, Florit A, Fragomeni SM, Zagaria L, Fragano A, Martinelli F, Ditto A, Seregni E, Scambia G, Raspagliesi F, Rufini V, Maccauro M
Gynecol Oncol 2023 Mar;170:153-159. Epub 2023 Jan 23 doi: 10.1016/j.ygyno.2023.01.011. PMID: 36696819
Deb PQ, Heller DS
J Low Genit Tract Dis 2023 Jan 1;27(1):40-46. Epub 2022 Sep 9 doi: 10.1097/LGT.0000000000000701. PMID: 36083687

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2024
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Vulvar Cancer, 2024

    Consumer resources

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