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Recurrent Rectal Carcinoma

MedGen UID:
82940
•Concept ID:
C0278554
•
Neoplastic Process
Synonyms: Rectal Cancer, Recurrent; Recurrent Cancer of Rectum; Recurrent Cancer of the Rectum; Recurrent Rectal Cancer

Definition

The reemergence of rectal carcinoma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Rectal Carcinoma

Professional guidelines

PubMed

Treatment of Locally Recurrent Rectal Carcinoma in Previously (Chemo)Irradiated Patients: A Review.
van der Meij W, Rombouts AJ, Rütten H, Bremers AJ, de Wilt JH
Dis Colon Rectum 2016 Feb;59(2):148-56. doi: 10.1097/DCR.0000000000000547. PMID: 26734974
Feasibility of reirradiation in the treatment of locally recurrent rectal cancer.
Bosman SJ, Holman FA, Nieuwenhuijzen GA, Martijn H, Creemers GJ, Rutten HJ
Br J Surg 2014 Sep;101(10):1280-9. Epub 2014 Jul 22 doi: 10.1002/bjs.9569. PMID: 25049111
Treatment of locally recurrent rectal carcinoma--results and prognostic factors.
Wong CS, Cummings BJ, Brierley JD, Catton CN, McLean M, Catton P, Hao Y
Int J Radiat Oncol Biol Phys 1998 Jan 15;40(2):427-35. doi: 10.1016/s0360-3016(97)00737-2. PMID: 9457832

Recent clinical studies

Etiology

CT-guided radioactive seed implantation for recurrent rectal carcinoma after multiple therapy.
Wang JJ, Yuan HS, Li JN, Jiang YL, Tian SQ, Yang RJ
Med Oncol 2010 Jun;27(2):421-9. Epub 2009 May 5 doi: 10.1007/s12032-009-9227-7. PMID: 19415534
Surgical treatment of locally recurrent rectal carcinoma.
Bozzetti F, Bertario L, Rossetti C, Gennari L, Andreola S, Baratti D, Gronchi A
Dis Colon Rectum 1997 Dec;40(12):1421-4. doi: 10.1007/BF02070705. PMID: 9407978
Recurrent rectal carcinoma after anterior resection and rectal stapling.
Anderberg B, Enblad P, Sjödahl R, Wetterfors J
Br J Surg 1984 Feb;71(2):98-100. doi: 10.1002/bjs.1800710206. PMID: 6692125
A prospective controlled evaluation of combined pelvic radiotherapy and methanol extraction residue of BCG (MER) for locally unresectable or recurrent rectal carcinoma.
O'Connell MJ, Childs DS, Moertel CG, Holbrook MA, Schutt AJ, Rubin J, Ritts RE Jr
Int J Radiat Oncol Biol Phys 1982 Jul;8(7):1115-9. doi: 10.1016/0360-3016(82)90057-8. PMID: 6181041
Gallium-67 citrate in detecting recurrent rectal carcinoma after abdomino-perineal resection.
Lentle BC, Dierich HC, Castor WR
J Can Assoc Radiol 1979 Sep;30(3):165-6. PMID: 468875

Diagnosis

Treatment of Locally Recurrent Rectal Carcinoma in Previously (Chemo)Irradiated Patients: A Review.
van der Meij W, Rombouts AJ, Rütten H, Bremers AJ, de Wilt JH
Dis Colon Rectum 2016 Feb;59(2):148-56. doi: 10.1097/DCR.0000000000000547. PMID: 26734974
Surgery for recurrent rectal carcinoma: The role of preoperative magnetic resonance imaging.
Messiou C, Chalmers A, Boyle K, Sagar P
Clin Radiol 2006 Mar;61(3):250-8. doi: 10.1016/j.crad.2005.11.008. PMID: 16488206
Diagnosis of recurrent rectal carcinoma by EUS-guided fine-needle aspiration.
Woodward T, Menke D
Gastrointest Endosc 2000 Feb;51(2):223-5. doi: 10.1016/s0016-5107(00)70426-3. PMID: 10650276
Surgical treatment of locally recurrent rectal carcinoma.
Bozzetti F, Bertario L, Rossetti C, Gennari L, Andreola S, Baratti D, Gronchi A
Dis Colon Rectum 1997 Dec;40(12):1421-4. doi: 10.1007/BF02070705. PMID: 9407978
Recurrent rectal carcinoma after anterior resection and rectal stapling.
Anderberg B, Enblad P, Sjödahl R, Wetterfors J
Br J Surg 1984 Feb;71(2):98-100. doi: 10.1002/bjs.1800710206. PMID: 6692125

Therapy

Treatment of Locally Recurrent Rectal Carcinoma in Previously (Chemo)Irradiated Patients: A Review.
van der Meij W, Rombouts AJ, Rütten H, Bremers AJ, de Wilt JH
Dis Colon Rectum 2016 Feb;59(2):148-56. doi: 10.1097/DCR.0000000000000547. PMID: 26734974
Early results from a phase I/II radiation dose-escalation study with concurrent amifostine and infusional 5-fluorouracil chemotherapy for preoperative treatment of unresectable or locally recurrent rectal carcinoma.
Myerson R, Zobeiri I, Birnbaum E, Dietz D, Fleshman J, Kodner I, Picus J, Ratkin G
Semin Oncol 2002 Dec;29(6 Suppl 19):29-33. doi: 10.1053/sonc.2002.37360. PMID: 12577240
Rationale for a phase I/II radiation dose-escalation study with concurrent amifostine (Ethyol) and infusional 5-FU chemotherapy for preoperative treatment of unresectable or locally recurrent rectal carcinoma.
Myerson R
Semin Radiat Oncol 2002 Jan;12(1 Suppl 1):86-90. doi: 10.1053/srao.2002.31380. PMID: 11917291
Pharmacokinetics of mitomycin C in pelvic stopflow infusion and hypoxic pelvic perfusion with and without hemofiltration: a pilot study of patients with recurrent unresectable rectal cancer.
Guadagni S, Aigner KR, Palumbo G, Cantore M, Fiorentini G, Pozone T, Deraco M, Clerico M, Chaudhuri PK
J Clin Pharmacol 1998 Oct;38(10):936-44. doi: 10.1002/j.1552-4604.1998.tb04390.x. PMID: 9807975
Recurrent rectal carcinoma after anterior resection and rectal stapling.
Anderberg B, Enblad P, Sjödahl R, Wetterfors J
Br J Surg 1984 Feb;71(2):98-100. doi: 10.1002/bjs.1800710206. PMID: 6692125

Prognosis

Treatment of Locally Recurrent Rectal Carcinoma in Previously (Chemo)Irradiated Patients: A Review.
van der Meij W, Rombouts AJ, Rütten H, Bremers AJ, de Wilt JH
Dis Colon Rectum 2016 Feb;59(2):148-56. doi: 10.1097/DCR.0000000000000547. PMID: 26734974
Intraoperative radiation therapy.
Willett CG
Int J Clin Oncol 2001 Oct;6(5):209-14. doi: 10.1007/pl00012107. PMID: 11723741
IORT for recurrent rectal carcinoma.
Eble MJ, Treiber M, Lehnert T, Herfarth C, Wannenmacher M
Front Radiat Ther Oncol 1997;31:229-33. doi: 10.1159/000061176. PMID: 9263829
Hypofractionation radiotherapy for a locally recurrent rectal carcinoma as a treatment for an elderly patient.
Rodrigues CI, Njo KH, Karim AB
Support Care Cancer 1993 Nov;1(6):334-5. doi: 10.1007/BF00364973. PMID: 7512411
A prospective controlled evaluation of combined pelvic radiotherapy and methanol extraction residue of BCG (MER) for locally unresectable or recurrent rectal carcinoma.
O'Connell MJ, Childs DS, Moertel CG, Holbrook MA, Schutt AJ, Rubin J, Ritts RE Jr
Int J Radiat Oncol Biol Phys 1982 Jul;8(7):1115-9. doi: 10.1016/0360-3016(82)90057-8. PMID: 6181041

Clinical prediction guides

Total pelvic exenteration for rectal cancer: outcomes and prognostic factors.
Domes TS, Colquhoun PH, Taylor B, Izawa JI, House AA, Luke PP, Izawa JI
Can J Surg 2011 Dec;54(6):387-93. doi: 10.1503/cjs.014010. PMID: 21939606Free PMC Article
Palliative interstitial HDR brachytherapy for recurrent rectal cancer. Implantation techniques and results.
Kolotas C, Röddiger S, Strassmann G, Martin T, Tselis N, Aebersold DM, Baltas D, Zamboglou N
Strahlenther Onkol 2003 Jul;179(7):458-63. doi: 10.1007/s00066-003-0921-7. PMID: 12835882
Adjuvant VHF therapy in locally recurrent and primary unresectable rectal cancer.
Trotter JM, Edis AJ, Blackwell JB, Lamb MH, Bayliss EJ, Shepherd JM, Cassidy B
Australas Radiol 1996 Aug;40(3):298-305. doi: 10.1111/j.1440-1673.1996.tb00407.x. PMID: 8826739
A prospective controlled evaluation of combined pelvic radiotherapy and methanol extraction residue of BCG (MER) for locally unresectable or recurrent rectal carcinoma.
O'Connell MJ, Childs DS, Moertel CG, Holbrook MA, Schutt AJ, Rubin J, Ritts RE Jr
Int J Radiat Oncol Biol Phys 1982 Jul;8(7):1115-9. doi: 10.1016/0360-3016(82)90057-8. PMID: 6181041
CT scanning in the male genital tract and in recurrent rectal carcinoma: a review.
Asbell SO
J Comput Tomogr 1981 Aug;5(3):244-55. doi: 10.1016/0149-936x(81)90040-0. PMID: 7285616

Recent systematic reviews

In search of a dose-response relationship with radiotherapy in the management of recurrent rectal carcinoma in the pelvis: a systematic review.
Wong R, Thomas G, Cummings B, Froud P, Shelley W, Withers R, Williams J
Int J Radiat Oncol Biol Phys 1998 Jan 15;40(2):437-46. doi: 10.1016/s0360-3016(97)00711-6. PMID: 9457833

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