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Recurrent Childhood Pineoblastoma

MedGen UID:
854380
•Concept ID:
C3887521
•
Neoplastic Process

Definition

The reemergence of pineoblastoma in childhood after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Childhood Pineoblastoma

Recent clinical studies

Etiology

Risk-adapted therapy and biological heterogeneity in pineoblastoma: integrated clinico-pathological analysis from the prospective, multi-center SJMB03 and SJYC07 trials.
Liu APY, Gudenas B, Lin T, Orr BA, Klimo P Jr, Kumar R, Bouffet E, Gururangan S, Crawford JR, Kellie SJ, Chintagumpala M, Fisher MJ, Bowers DC, Hassall T, Indelicato DJ, Onar-Thomas A, Ellison DW, Boop FA, Merchant TE, Robinson GW, Northcott PA, Gajjar A
Acta Neuropathol 2020 Feb;139(2):259-271. Epub 2019 Dec 4 doi: 10.1007/s00401-019-02106-9. PMID: 31802236Free PMC Article
Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma.
Snuderl M, Kannan K, Pfaff E, Wang S, Stafford JM, Serrano J, Heguy A, Ray K, Faustin A, Aminova O, Dolgalev I, Stapleton SL, Zagzag D, Chiriboga L, Gardner SL, Wisoff JH, Golfinos JG, Capper D, Hovestadt V, Rosenblum MK, Placantonakis DG, LeBoeuf SE, Papagiannakopoulos TY, Chavez L, Ahsan S, Eberhart CG, Pfister SM, Jones DTW, Karajannis MA
Nat Commun 2018 Jul 20;9(1):2868. doi: 10.1038/s41467-018-05029-3. PMID: 30030436Free PMC Article
The postirradiation incidence of cavernous angioma is higher in patients with childhood pineoblastoma or primitive neuroectodermal tumors than medulloblastoma.
Yamasaki F, Takayasu T, Nosaka R, Kenjo M, Akiyama Y, Tominaga A, Sugiyama K, Kobayashi M, Kurisu K
Childs Nerv Syst 2015 Jun;31(6):901-7. Epub 2015 Feb 18 doi: 10.1007/s00381-015-2626-5. PMID: 25690449
Pinealoblastomas in children.
Cuccia V, Rodríguez F, Palma F, Zuccaro G
Childs Nerv Syst 2006 Jun;22(6):577-85. Epub 2006 Mar 23 doi: 10.1007/s00381-006-0095-6. PMID: 16555075
Pineal tumors: experience with 48 cases over 10 years.
Cho BK, Wang KC, Nam DH, Kim DG, Jung HW, Kim HJ, Han DH, Choi KS
Childs Nerv Syst 1998 Jan-Feb;14(1-2):53-8. doi: 10.1007/s003810050175. PMID: 9548342

Diagnosis

Risk-adapted therapy and biological heterogeneity in pineoblastoma: integrated clinico-pathological analysis from the prospective, multi-center SJMB03 and SJYC07 trials.
Liu APY, Gudenas B, Lin T, Orr BA, Klimo P Jr, Kumar R, Bouffet E, Gururangan S, Crawford JR, Kellie SJ, Chintagumpala M, Fisher MJ, Bowers DC, Hassall T, Indelicato DJ, Onar-Thomas A, Ellison DW, Boop FA, Merchant TE, Robinson GW, Northcott PA, Gajjar A
Acta Neuropathol 2020 Feb;139(2):259-271. Epub 2019 Dec 4 doi: 10.1007/s00401-019-02106-9. PMID: 31802236Free PMC Article
The postirradiation incidence of cavernous angioma is higher in patients with childhood pineoblastoma or primitive neuroectodermal tumors than medulloblastoma.
Yamasaki F, Takayasu T, Nosaka R, Kenjo M, Akiyama Y, Tominaga A, Sugiyama K, Kobayashi M, Kurisu K
Childs Nerv Syst 2015 Jun;31(6):901-7. Epub 2015 Feb 18 doi: 10.1007/s00381-015-2626-5. PMID: 25690449
Pineocytomas of childhood. A reappraisal of natural history and response to therapy.
D'Andrea AD, Packer RJ, Rorke LB, Bilaniuk LT, Sutton LN, Bruce DA, Schut L
Cancer 1987 Apr 1;59(7):1353-7. doi: 10.1002/1097-0142(19870401)59:7<1353::aid-cncr2820590720>3.0.co;2-4. PMID: 3815306
Carboplatin and recurrent childhood brain tumors.
Allen JC, Walker R, Luks E, Jennings M, Barfoot S, Tan C
J Clin Oncol 1987 Mar;5(3):459-63. doi: 10.1200/JCO.1987.5.3.459. PMID: 3546620
Pineal region tumors of childhood.
Packer RJ, Sutton LN, Rosenstock JG, Rorke LB, Bilaniuk LT, Zimmerman RA, Littman PA, Bruce DA, Schut L
Pediatrics 1984 Jul;74(1):97-102. PMID: 6739222

Therapy

Risk-adapted therapy and biological heterogeneity in pineoblastoma: integrated clinico-pathological analysis from the prospective, multi-center SJMB03 and SJYC07 trials.
Liu APY, Gudenas B, Lin T, Orr BA, Klimo P Jr, Kumar R, Bouffet E, Gururangan S, Crawford JR, Kellie SJ, Chintagumpala M, Fisher MJ, Bowers DC, Hassall T, Indelicato DJ, Onar-Thomas A, Ellison DW, Boop FA, Merchant TE, Robinson GW, Northcott PA, Gajjar A
Acta Neuropathol 2020 Feb;139(2):259-271. Epub 2019 Dec 4 doi: 10.1007/s00401-019-02106-9. PMID: 31802236Free PMC Article
Pinealoblastomas in children.
Cuccia V, Rodríguez F, Palma F, Zuccaro G
Childs Nerv Syst 2006 Jun;22(6):577-85. Epub 2006 Mar 23 doi: 10.1007/s00381-006-0095-6. PMID: 16555075
Cisplatin, ara-C and etoposide (PAE) in the treatment of recurrent childhood brain tumors.
Corden BJ, Strauss LC, Killmond T, Carson BS, Wharam MD, Kumar AJ, Piantadosi S, Robb PA, Phillips PC
J Neurooncol 1991 Aug;11(1):57-63. doi: 10.1007/BF00166998. PMID: 1919647
Carboplatin and recurrent childhood brain tumors.
Allen JC, Walker R, Luks E, Jennings M, Barfoot S, Tan C
J Clin Oncol 1987 Mar;5(3):459-63. doi: 10.1200/JCO.1987.5.3.459. PMID: 3546620
Pineal region tumors of childhood.
Packer RJ, Sutton LN, Rosenstock JG, Rorke LB, Bilaniuk LT, Zimmerman RA, Littman PA, Bruce DA, Schut L
Pediatrics 1984 Jul;74(1):97-102. PMID: 6739222

Prognosis

Risk-adapted therapy and biological heterogeneity in pineoblastoma: integrated clinico-pathological analysis from the prospective, multi-center SJMB03 and SJYC07 trials.
Liu APY, Gudenas B, Lin T, Orr BA, Klimo P Jr, Kumar R, Bouffet E, Gururangan S, Crawford JR, Kellie SJ, Chintagumpala M, Fisher MJ, Bowers DC, Hassall T, Indelicato DJ, Onar-Thomas A, Ellison DW, Boop FA, Merchant TE, Robinson GW, Northcott PA, Gajjar A
Acta Neuropathol 2020 Feb;139(2):259-271. Epub 2019 Dec 4 doi: 10.1007/s00401-019-02106-9. PMID: 31802236Free PMC Article
Pinealoblastomas in children.
Cuccia V, Rodríguez F, Palma F, Zuccaro G
Childs Nerv Syst 2006 Jun;22(6):577-85. Epub 2006 Mar 23 doi: 10.1007/s00381-006-0095-6. PMID: 16555075
Pineal tumors: experience with 48 cases over 10 years.
Cho BK, Wang KC, Nam DH, Kim DG, Jung HW, Kim HJ, Han DH, Choi KS
Childs Nerv Syst 1998 Jan-Feb;14(1-2):53-8. doi: 10.1007/s003810050175. PMID: 9548342
Cisplatin, ara-C and etoposide (PAE) in the treatment of recurrent childhood brain tumors.
Corden BJ, Strauss LC, Killmond T, Carson BS, Wharam MD, Kumar AJ, Piantadosi S, Robb PA, Phillips PC
J Neurooncol 1991 Aug;11(1):57-63. doi: 10.1007/BF00166998. PMID: 1919647
PCNU and recurrent childhood brain tumors.
Allen JC, Hancock C, Walker R, Tan C
J Neurooncol 1987;5(3):241-4. doi: 10.1007/BF00151228. PMID: 3681386

Clinical prediction guides

The applicability of Collins' Law to childhood brain tumors and its usefulness as a predictor of survival.
Brown WD, Tavaré CJ, Sobel EL, Gilles FH
Neurosurgery 1995 Jun;36(6):1093-6. doi: 10.1227/00006123-199506000-00004. PMID: 7643986
Cisplatin, ara-C and etoposide (PAE) in the treatment of recurrent childhood brain tumors.
Corden BJ, Strauss LC, Killmond T, Carson BS, Wharam MD, Kumar AJ, Piantadosi S, Robb PA, Phillips PC
J Neurooncol 1991 Aug;11(1):57-63. doi: 10.1007/BF00166998. PMID: 1919647
PCNU and recurrent childhood brain tumors.
Allen JC, Hancock C, Walker R, Tan C
J Neurooncol 1987;5(3):241-4. doi: 10.1007/BF00151228. PMID: 3681386

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