U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Childhood Central Nervous System Embryonal Tumor

MedGen UID:
859266
Concept ID:
C3899672
Neoplastic Process
Synonym: Childhood Central Nervous System Embryonal Neoplasm

Definition

A central nervous system embryonal tumor that occurs during childhood. [from NCI]

Professional guidelines

PubMed

Gan HW, Morillon P, Albanese A, Aquilina K, Chandler C, Chang YC, Drimtzias E, Farndon S, Jacques TS, Korbonits M, Kuczynski A, Limond J, Robinson L, Simmons I, Thomas N, Thomas S, Thorp N, Vargha-Khadem F, Warren D, Zebian B, Mallucci C, Spoudeas HA
Lancet Diabetes Endocrinol 2023 Sep;11(9):694-706. Epub 2023 Aug 4 doi: 10.1016/S2213-8587(23)00162-6. PMID: 37549682
Capper D, Reifenberger G, French PJ, Schweizer L, Weller M, Touat M, Niclou SP, Euskirchen P, Haberler C, Hegi ME, Brandner S, Le Rhun E, Rudà R, Sanson M, Tabatabai G, Sahm F, Wen PY, Wesseling P, Preusser M, van den Bent MJ
Neuro Oncol 2023 May 4;25(5):813-826. doi: 10.1093/neuonc/noad008. PMID: 36632791Free PMC Article
Schulte FJ
Neuropediatrics 1984 Feb;15(1):3-12. doi: 10.1055/s-2008-1052332. PMID: 6324015

Recent clinical studies

Etiology

Fangusaro J, Jones DT, Packer RJ, Gutmann DH, Milde T, Witt O, Mueller S, Fisher MJ, Hansford JR, Tabori U, Hargrave D, Bandopadhayay P
Neuro Oncol 2024 Jan 5;26(1):25-37. doi: 10.1093/neuonc/noad195. PMID: 37944912Free PMC Article
Taylor KR, Monje M
Nat Rev Neurosci 2023 Dec;24(12):733-746. Epub 2023 Oct 19 doi: 10.1038/s41583-023-00744-3. PMID: 37857838Free PMC Article
Gan HW, Morillon P, Albanese A, Aquilina K, Chandler C, Chang YC, Drimtzias E, Farndon S, Jacques TS, Korbonits M, Kuczynski A, Limond J, Robinson L, Simmons I, Thomas N, Thomas S, Thorp N, Vargha-Khadem F, Warren D, Zebian B, Mallucci C, Spoudeas HA
Lancet Diabetes Endocrinol 2023 Sep;11(9):694-706. Epub 2023 Aug 4 doi: 10.1016/S2213-8587(23)00162-6. PMID: 37549682
Chan GC, Chan CM
Biomolecules 2022 Feb 24;12(3) doi: 10.3390/biom12030358. PMID: 35327550Free PMC Article
Northcott PA, Robinson GW, Kratz CP, Mabbott DJ, Pomeroy SL, Clifford SC, Rutkowski S, Ellison DW, Malkin D, Taylor MD, Gajjar A, Pfister SM
Nat Rev Dis Primers 2019 Feb 14;5(1):11. doi: 10.1038/s41572-019-0063-6. PMID: 30765705

Diagnosis

Gan HW, Morillon P, Albanese A, Aquilina K, Chandler C, Chang YC, Drimtzias E, Farndon S, Jacques TS, Korbonits M, Kuczynski A, Limond J, Robinson L, Simmons I, Thomas N, Thomas S, Thorp N, Vargha-Khadem F, Warren D, Zebian B, Mallucci C, Spoudeas HA
Lancet Diabetes Endocrinol 2023 Sep;11(9):694-706. Epub 2023 Aug 4 doi: 10.1016/S2213-8587(23)00162-6. PMID: 37549682
Northcott PA, Robinson GW, Kratz CP, Mabbott DJ, Pomeroy SL, Clifford SC, Rutkowski S, Ellison DW, Malkin D, Taylor MD, Gajjar A, Pfister SM
Nat Rev Dis Primers 2019 Feb 14;5(1):11. doi: 10.1038/s41572-019-0063-6. PMID: 30765705
Udaka YT, Packer RJ
Neurol Clin 2018 Aug;36(3):533-556. doi: 10.1016/j.ncl.2018.04.009. PMID: 30072070
Aygun N
Curr Pediatr Rev 2018;14(2):73-90. doi: 10.2174/1573396314666180129101627. PMID: 29380702
Reddy AT, Packer RJ
Curr Opin Oncol 1998 May;10(3):186-93. doi: 10.1097/00001622-199805000-00003. PMID: 9619353

Therapy

Vitanza NA, Wilson AL, Huang W, Seidel K, Brown C, Gustafson JA, Yokoyama JK, Johnson AJ, Baxter BA, Koning RW, Reid AN, Meechan M, Biery MC, Myers C, Rawlings-Rhea SD, Albert CM, Browd SR, Hauptman JS, Lee A, Ojemann JG, Berens ME, Dun MD, Foster JB, Crotty EE, Leary SES, Cole BL, Perez FA, Wright JN, Orentas RJ, Chour T, Newell EW, Whiteaker JR, Zhao L, Paulovich AG, Pinto N, Gust J, Gardner RA, Jensen MC, Park JR
Cancer Discov 2023 Jan 9;13(1):114-131. doi: 10.1158/2159-8290.CD-22-0750. PMID: 36259971Free PMC Article
Chan GC, Chan CM
Biomolecules 2022 Feb 24;12(3) doi: 10.3390/biom12030358. PMID: 35327550Free PMC Article
Ebrahimi-Fakhari D, Franz DN
Expert Opin Pharmacother 2020 Aug;21(11):1329-1336. Epub 2020 Apr 27 doi: 10.1080/14656566.2020.1751124. PMID: 32338549
May JA, Krieger MD, Bowen I, Geffner ME
Adv Pediatr 2006;53:183-209. doi: 10.1016/j.yapd.2006.04.013. PMID: 17089867
Reddy AT, Packer RJ
Curr Opin Oncol 1998 May;10(3):186-93. doi: 10.1097/00001622-199805000-00003. PMID: 9619353

Prognosis

González IA, Stewart DR, Schultz KAP, Field AP, Hill DA, Dehner LP
Mod Pathol 2022 Jan;35(1):4-22. Epub 2021 Oct 1 doi: 10.1038/s41379-021-00905-8. PMID: 34599283Free PMC Article
Northcott PA, Robinson GW, Kratz CP, Mabbott DJ, Pomeroy SL, Clifford SC, Rutkowski S, Ellison DW, Malkin D, Taylor MD, Gajjar A, Pfister SM
Nat Rev Dis Primers 2019 Feb 14;5(1):11. doi: 10.1038/s41572-019-0063-6. PMID: 30765705
Aygun N
Curr Pediatr Rev 2018;14(2):73-90. doi: 10.2174/1573396314666180129101627. PMID: 29380702
Robison NJ, Kieran MW
J Neurooncol 2014 Aug;119(1):7-15. Epub 2014 May 3 doi: 10.1007/s11060-014-1448-8. PMID: 24792486
Reddy AT, Packer RJ
Curr Opin Oncol 1998 May;10(3):186-93. doi: 10.1097/00001622-199805000-00003. PMID: 9619353

Clinical prediction guides

Aygun N
Curr Pediatr Rev 2018;14(2):73-90. doi: 10.2174/1573396314666180129101627. PMID: 29380702
Müller HL
Curr Opin Endocrinol Diabetes Obes 2016 Feb;23(1):81-9. doi: 10.1097/MED.0000000000000214. PMID: 26574645Free PMC Article
Reis GF, Tihan T
Semin Pediatr Neurol 2015 Mar;22(1):23-7. Epub 2014 Dec 10 doi: 10.1016/j.spen.2014.12.001. PMID: 25976257
Massimino M, Giangaspero F, Garrè ML, Gandola L, Poggi G, Biassoni V, Gatta G, Rutkowski S
Crit Rev Oncol Hematol 2011 Jul;79(1):65-83. Epub 2010 Dec 3 doi: 10.1016/j.critrevonc.2010.07.010. PMID: 21129995
May JA, Krieger MD, Bowen I, Geffner ME
Adv Pediatr 2006;53:183-209. doi: 10.1016/j.yapd.2006.04.013. PMID: 17089867

Recent systematic reviews

Ajithkumar T, Avanzo M, Yorke E, Tsang DS, Milano MT, Olch AJ, Merchant TE, Dieckmann K, Mahajan A, Fuji H, Paulino AC, Timmermann B, Marks LB, Bentzen SM, Jackson A, Constine LS
Int J Radiat Oncol Biol Phys 2024 Jun 1;119(2):655-668. Epub 2024 Feb 1 doi: 10.1016/j.ijrobp.2023.12.043. PMID: 38300187
Paquette K, Coltin H, Boivin A, Amre D, Nuyt AM, Luu TM
PLoS One 2019;14(1):e0210366. Epub 2019 Jan 4 doi: 10.1371/journal.pone.0210366. PMID: 30608983Free PMC Article
Kreis C, Doessegger E, Lupatsch JE, Spycher BD
Eur J Epidemiol 2019 Jan;34(1):9-21. Epub 2018 Nov 16 doi: 10.1007/s10654-018-0456-y. PMID: 30446850Free PMC Article
Georgakis MK, Kalogirou EI, Liaskas A, Karalexi MA, Papathoma P, Ladopoulou K, Kantzanou M, Tsivgoulis G; NARECHEM-BT Working Group, Petridou ET
Eur J Cancer 2017 Apr;75:117-131. Epub 2017 Feb 20 doi: 10.1016/j.ejca.2016.12.033. PMID: 28219020
Martin RM, Gunnell D, Owen CG, Smith GD
Int J Cancer 2005 Dec 20;117(6):1020-31. doi: 10.1002/ijc.21274. PMID: 15986434

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...