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Childhood Oligoastrocytoma

MedGen UID:
859243
•Concept ID:
C3899649
•
Neoplastic Process

Definition

An oligoastrocytoma that occurs during childhood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChildhood Oligoastrocytoma

Professional guidelines

PubMed

Disseminated glioneuronal tumors occurring in childhood: treatment outcomes and BRAF alterations including V600E mutation.
Dodgshun AJ, SantaCruz N, Hwang J, Ramkissoon SH, Malkin H, Bergthold G, Manley P, Chi S, MacGregor D, Goumnerova L, Sullivan M, Ligon K, Beroukhim R, Herrington B, Kieran MW, Hansford JR, Bandopadhayay P
J Neurooncol 2016 Jun;128(2):293-302. Epub 2016 Mar 19 doi: 10.1007/s11060-016-2109-x. PMID: 26994902
The impact of technical adjuncts in the surgical management of cerebral hemispheric low-grade gliomas of childhood.
Berger MS
J Neurooncol 1996 May-Jun;28(2-3):129-55. doi: 10.1007/BF00250195. PMID: 8832458
Role of radiation therapy in the management of neoplasms of the central nervous system.
Mayer EG, Boone ML, Aristizabal SA
Adv Neurol 1976;15:201-20. PMID: 180777

Recent clinical studies

Etiology

Oligosarcomas, IDH-mutant are distinct and aggressive.
Suwala AK, Felix M, Friedel D, Stichel D, Schrimpf D, Hinz F, Hewer E, Schweizer L, Dohmen H, Pohl U, Staszewski O, Korshunov A, Stein M, Wongsurawat T, Cheunsuacchon P, Sathornsumetee S, Koelsche C, Turner C, Le Rhun E, Mühlebner A, Schucht P, Özduman K, Ono T, Shimizu H, Prinz M, Acker T, Herold-Mende C, Kessler T, Wick W, Capper D, Wesseling P, Sahm F, von Deimling A, Hartmann C, Reuss DE
Acta Neuropathol 2022 Feb;143(2):263-281. Epub 2021 Dec 30 doi: 10.1007/s00401-021-02395-z. PMID: 34967922Free PMC Article
Molecular pathways in gliomagenesis and their relevance to neuropathologic diagnosis.
Appin CL, Brat DJ
Adv Anat Pathol 2015 Jan;22(1):50-8. doi: 10.1097/PAP.0000000000000048. PMID: 25461780
Surgical outcomes of cerebellar tumors in children.
Akay KM, Izci Y, Baysefer A, Atabey C, Kismet E, Timurkaynak E
Pediatr Neurosurg 2004 Sep-Oct;40(5):220-5. doi: 10.1159/000082295. PMID: 15687736
The impact of technical adjuncts in the surgical management of cerebral hemispheric low-grade gliomas of childhood.
Berger MS
J Neurooncol 1996 May-Jun;28(2-3):129-55. doi: 10.1007/BF00250195. PMID: 8832458
Malignant hemispheric tumors in childhood.
Hoppe-Hirsch E, Hirsch JF, Lellouch-Tubiana A, Pierre-Kahn A, Sainte-Rose C, Renier D
Childs Nerv Syst 1993 Jun;9(3):131-5. doi: 10.1007/BF00272260. PMID: 8397066

Diagnosis

Oligosarcomas, IDH-mutant are distinct and aggressive.
Suwala AK, Felix M, Friedel D, Stichel D, Schrimpf D, Hinz F, Hewer E, Schweizer L, Dohmen H, Pohl U, Staszewski O, Korshunov A, Stein M, Wongsurawat T, Cheunsuacchon P, Sathornsumetee S, Koelsche C, Turner C, Le Rhun E, Mühlebner A, Schucht P, Özduman K, Ono T, Shimizu H, Prinz M, Acker T, Herold-Mende C, Kessler T, Wick W, Capper D, Wesseling P, Sahm F, von Deimling A, Hartmann C, Reuss DE
Acta Neuropathol 2022 Feb;143(2):263-281. Epub 2021 Dec 30 doi: 10.1007/s00401-021-02395-z. PMID: 34967922Free PMC Article
Molecular genetics of gliomas.
Appin CL, Brat DJ
Cancer J 2014 Jan-Feb;20(1):66-72. doi: 10.1097/PPO.0000000000000020. PMID: 24445767
Surgical outcomes of cerebellar tumors in children.
Akay KM, Izci Y, Baysefer A, Atabey C, Kismet E, Timurkaynak E
Pediatr Neurosurg 2004 Sep-Oct;40(5):220-5. doi: 10.1159/000082295. PMID: 15687736
The impact of technical adjuncts in the surgical management of cerebral hemispheric low-grade gliomas of childhood.
Berger MS
J Neurooncol 1996 May-Jun;28(2-3):129-55. doi: 10.1007/BF00250195. PMID: 8832458
CT and MRI aspects of supratentorial hemispheric tumors of childhood and adolescence.
Finizio FS
Childs Nerv Syst 1995 Oct;11(10):559-67. doi: 10.1007/BF00300993. PMID: 8556721

Therapy

Molecular classification of anaplastic oligodendroglioma using next-generation sequencing: a report of the prospective randomized EORTC Brain Tumor Group 26951 phase III trial.
Dubbink HJ, Atmodimedjo PN, Kros JM, French PJ, Sanson M, Idbaih A, Wesseling P, Enting R, Spliet W, Tijssen C, Dinjens WN, Gorlia T, van den Bent MJ
Neuro Oncol 2016 Mar;18(3):388-400. Epub 2015 Sep 9 doi: 10.1093/neuonc/nov182. PMID: 26354927Free PMC Article
Anaplastic oligodendroglioma after childhood acute lymphoblastic leukemia: chemotherapy and autologous peripheral blood stem cell transplantation.
Hah JO
J Pediatr Hematol Oncol 2008 Oct;30(10):764-7. doi: 10.1097/MPH.0b013e31817e4a55. PMID: 19011476
Treatment of optic pathway hypothalamic gliomas in childhood: experience with 18 consecutive cases.
Jaing TH, Lin KL, Tsay PK, Hsueh C, Hung PC, Wu CT, Tseng CK
J Pediatr Hematol Oncol 2008 Mar;30(3):222-4. doi: 10.1097/MPH.0b013e318162bd6a. PMID: 18376285
Disseminating anaplastic brainstem oligodendroglioma associated with allelic loss in the tumor suppressor candidate region D19S246 of chromosome 19 mimicking an inflammatory central nervous system disease in a 9-year-old boy.
Mittelbronn M, Wolff M, Bültmann E, Nägele T, Capper D, Beck R, Meyermann R, Beschorner R
Hum Pathol 2005 Jul;36(7):854-7. doi: 10.1016/j.humpath.2005.05.017. PMID: 16084959
Carboplatin hypersensitivity in children. A report of five patients with brain tumors.
Chang SM, Fryberger S, Crouse V, Tilford D, Prados MD
Cancer 1995 Mar 1;75(5):1171-5. doi: 10.1002/1097-0142(19950301)75:5<1171::aid-cncr2820750518>3.0.co;2-f. PMID: 7850717

Prognosis

Oligosarcomas, IDH-mutant are distinct and aggressive.
Suwala AK, Felix M, Friedel D, Stichel D, Schrimpf D, Hinz F, Hewer E, Schweizer L, Dohmen H, Pohl U, Staszewski O, Korshunov A, Stein M, Wongsurawat T, Cheunsuacchon P, Sathornsumetee S, Koelsche C, Turner C, Le Rhun E, Mühlebner A, Schucht P, Özduman K, Ono T, Shimizu H, Prinz M, Acker T, Herold-Mende C, Kessler T, Wick W, Capper D, Wesseling P, Sahm F, von Deimling A, Hartmann C, Reuss DE
Acta Neuropathol 2022 Feb;143(2):263-281. Epub 2021 Dec 30 doi: 10.1007/s00401-021-02395-z. PMID: 34967922Free PMC Article
Molecular pathways in gliomagenesis and their relevance to neuropathologic diagnosis.
Appin CL, Brat DJ
Adv Anat Pathol 2015 Jan;22(1):50-8. doi: 10.1097/PAP.0000000000000048. PMID: 25461780
Molecular genetics of gliomas.
Appin CL, Brat DJ
Cancer J 2014 Jan-Feb;20(1):66-72. doi: 10.1097/PPO.0000000000000020. PMID: 24445767
CT and MRI aspects of supratentorial hemispheric tumors of childhood and adolescence.
Finizio FS
Childs Nerv Syst 1995 Oct;11(10):559-67. doi: 10.1007/BF00300993. PMID: 8556721
Oligodendroglioma in childhood.
Wang KC, Chi JG, Cho BK
J Korean Med Sci 1993 Apr;8(2):110-6. doi: 10.3346/jkms.1993.8.2.110. PMID: 8397926Free PMC Article

Clinical prediction guides

Molecular pathways in gliomagenesis and their relevance to neuropathologic diagnosis.
Appin CL, Brat DJ
Adv Anat Pathol 2015 Jan;22(1):50-8. doi: 10.1097/PAP.0000000000000048. PMID: 25461780
Molecular genetics of gliomas.
Appin CL, Brat DJ
Cancer J 2014 Jan-Feb;20(1):66-72. doi: 10.1097/PPO.0000000000000020. PMID: 24445767
CT and MRI aspects of supratentorial hemispheric tumors of childhood and adolescence.
Finizio FS
Childs Nerv Syst 1995 Oct;11(10):559-67. doi: 10.1007/BF00300993. PMID: 8556721
Oligodendroglioma in childhood.
Wang KC, Chi JG, Cho BK
J Korean Med Sci 1993 Apr;8(2):110-6. doi: 10.3346/jkms.1993.8.2.110. PMID: 8397926Free PMC Article
Malignant hemispheric tumors in childhood.
Hoppe-Hirsch E, Hirsch JF, Lellouch-Tubiana A, Pierre-Kahn A, Sainte-Rose C, Renier D
Childs Nerv Syst 1993 Jun;9(3):131-5. doi: 10.1007/BF00272260. PMID: 8397066

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