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Malignant ovarian Brenner tumor

MedGen UID:
90793
•Concept ID:
C0334495
•
Neoplastic Process
Synonyms: Brenner Tumor, Malignant; Malignant Brenner Tumor
SNOMED CT: Malignant Brenner tumor (42194009); Malignant Brenner tumor of ovary (1296848002); Brenner tumor, malignant (42194009)
 
Monarch Initiative: MONDO:0002920

Definition

A malignant neoplasm that arises from the ovary. It is characterized by the presence of an invasive malignant urothelial-type cellular component and nests of benign urothelial-type cells in a fibrotic stroma. When the neoplasm is confined to the ovary, the prognosis is good. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant ovarian Brenner tumor

Professional guidelines

PubMed

Bispecific antibodies and autologous chimeric antigen receptor T cell therapies for treatment of hematological malignancies.
Al Hadidi S, Heslop HE, Brenner MK, Suzuki M
Mol Ther 2024 Aug 7;32(8):2444-2460. Epub 2024 May 31 doi: 10.1016/j.ymthe.2024.05.039. PMID: 38822527Free PMC Article
Crohn's disease - treatment with biological medication.
Zaltman C, Amarante H, Brenner MM, Costa MHM, Flores C, Leal RF, Grain JFS, Zeroncio M
Rev Assoc Med Bras (1992) 2019 May 2;65(4):554-567. doi: 10.1590/1806-9282.65.4.554. PMID: 31066809
Response: Methods for second primary cancers evaluation have to be standardized.
Chen T, Brenner H, Fallah M, Jansen L, Castro FA, Geiss K, Holleczek B, Katalinic A, Luttmann S, Sundquist K, Ressing M, Xu L, Hemminki K; GEKID Cancer Survival Working Group
Int J Cancer 2018 Mar 15;142(6):1286-1287. Epub 2017 Nov 24 doi: 10.1002/ijc.31151. PMID: 29134649

Recent clinical studies

Diagnosis

A Rare Case of Ruptured Malignant Ovarian Brenner Tumor.
Kurniadi A, Anfasa MK, Agustina H, Dewayani BM, Kireina J
Am J Case Rep 2023 Feb 13;24:e938680. doi: 10.12659/AJCR.938680. PMID: 36775948Free PMC Article

Supplemental Content

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