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Herpes simplex infectious disease

MedGen UID:
9234
•Concept ID:
C0019348
•
Disease or Syndrome
Synonyms: Herpes Simplex; Herpes Simplex Virus Infection
SNOMED CT: Herpes simplex (88594005); Herpes simplex complex (88594005); Herpes simplex infection (88594005); Herpes simplex viral infection (88594005)
 
Monarch Initiative: MONDO:0004609

Definition

An infection that is caused by herpes simplex virus. [from NCI]

Professional guidelines

PubMed

Diagnosis and Treatment of Sexually Transmitted Infections: A Review.
Tuddenham S, Hamill MM, Ghanem KG
JAMA 2022 Jan 11;327(2):161-172. doi: 10.1001/jama.2021.23487. PMID: 35015033
Sexually Transmitted Infections Treatment Guidelines, 2021.
Workowski KA, Bachmann LH, Chan PA, Johnston CM, Muzny CA, Park I, Reno H, Zenilman JM, Bolan GA
MMWR Recomm Rep 2021 Jul 23;70(4):1-187. doi: 10.15585/mmwr.rr7004a1. PMID: 34292926Free PMC Article
Genital Ulcers: Differential Diagnosis and Management.
Roett MA
Am Fam Physician 2020 Mar 15;101(6):355-361. PMID: 32163252

Recent clinical studies

Etiology

Management of Genital Herpes in Pregnancy: ACOG Practice Bulletinacog Practice Bulletin, Number 220.
Obstet Gynecol 2020 May;135(5):e193-e202. doi: 10.1097/AOG.0000000000003840. PMID: 32332414
Management of Genital Herpes in Pregnancy: ACOG Practice Bulletin Summary, Number 220.
Obstet Gynecol 2020 May;135(5):1236-1238. doi: 10.1097/AOG.0000000000003841. PMID: 32332408
Neonatal herpes simplex virus infections.
Pinninti SG, Kimberlin DW
Semin Perinatol 2018 Apr;42(3):168-175. Epub 2018 Mar 12 doi: 10.1053/j.semperi.2018.02.004. PMID: 29544668
Genital Herpes: A Review.
Groves MJ
Am Fam Physician 2016 Jun 1;93(11):928-34. PMID: 27281837
Genital herpes.
Gupta R, Warren T, Wald A
Lancet 2007 Dec 22;370(9605):2127-37. doi: 10.1016/S0140-6736(07)61908-4. PMID: 18156035

Diagnosis

Genital Herpes Infection: Progress and Problems.
Van Wagoner N, Qushair F, Johnston C
Infect Dis Clin North Am 2023 Jun;37(2):351-367. doi: 10.1016/j.idc.2023.02.011. PMID: 37105647
Genital Herpes Simplex Virus-An Updated Review.
Omarova S, Cannon A, Weiss W, Bruccoleri A, Puccio J
Adv Pediatr 2022 Aug;69(1):149-162. Epub 2022 Jun 21 doi: 10.1016/j.yapd.2022.03.010. PMID: 35985707
Diagnosis and Treatment of Sexually Transmitted Infections: A Review.
Tuddenham S, Hamill MM, Ghanem KG
JAMA 2022 Jan 11;327(2):161-172. doi: 10.1001/jama.2021.23487. PMID: 35015033
Herpes Simplex Virus: Epidemiology, Diagnosis, and Treatment.
Cole S
Nurs Clin North Am 2020 Sep;55(3):337-345. Epub 2020 Jul 15 doi: 10.1016/j.cnur.2020.05.004. PMID: 32762854
Human herpes simplex virus infections: epidemiology, pathogenesis, symptomatology, diagnosis, and management.
Fatahzadeh M, Schwartz RA
J Am Acad Dermatol 2007 Nov;57(5):737-63; quiz 764-6. doi: 10.1016/j.jaad.2007.06.027. PMID: 17939933

Therapy

Herpes Simplex Virus: Epidemiology, Diagnosis, and Treatment.
Cole S
Nurs Clin North Am 2020 Sep;55(3):337-345. Epub 2020 Jul 15 doi: 10.1016/j.cnur.2020.05.004. PMID: 32762854
Management of Genital Herpes in Pregnancy: ACOG Practice Bulletinacog Practice Bulletin, Number 220.
Obstet Gynecol 2020 May;135(5):e193-e202. doi: 10.1097/AOG.0000000000003840. PMID: 32332414
Management of Genital Herpes in Pregnancy: ACOG Practice Bulletin Summary, Number 220.
Obstet Gynecol 2020 May;135(5):1236-1238. doi: 10.1097/AOG.0000000000003841. PMID: 32332408
Neonatal herpes simplex virus infections.
Pinninti SG, Kimberlin DW
Semin Perinatol 2018 Apr;42(3):168-175. Epub 2018 Mar 12 doi: 10.1053/j.semperi.2018.02.004. PMID: 29544668
Human herpes simplex virus infections: epidemiology, pathogenesis, symptomatology, diagnosis, and management.
Fatahzadeh M, Schwartz RA
J Am Acad Dermatol 2007 Nov;57(5):737-63; quiz 764-6. doi: 10.1016/j.jaad.2007.06.027. PMID: 17939933

Prognosis

40 Years after the Registration of Acyclovir: Do We Need New Anti-Herpetic Drugs?
Majewska A, Mlynarczyk-Bonikowska B
Int J Mol Sci 2022 Mar 22;23(7) doi: 10.3390/ijms23073431. PMID: 35408788Free PMC Article
Herpes simplex virus: global infection prevalence and incidence estimates, 2016.
James C, Harfouche M, Welton NJ, Turner KM, Abu-Raddad LJ, Gottlieb SL, Looker KJ
Bull World Health Organ 2020 May 1;98(5):315-329. Epub 2020 Mar 25 doi: 10.2471/BLT.19.237149. PMID: 32514197Free PMC Article
Neonatal herpes simplex virus infections.
Pinninti SG, Kimberlin DW
Semin Perinatol 2018 Apr;42(3):168-175. Epub 2018 Mar 12 doi: 10.1053/j.semperi.2018.02.004. PMID: 29544668
Herpes simplex virus.
Waggoner-Fountain LA, Grossman LB
Pediatr Rev 2004 Mar;25(3):86-93. doi: 10.1542/pir.25-3-86. PMID: 14993516
Herpes simplex viruses 1 and 2.
Yeung-Yue KA, Brentjens MH, Lee PC, Tyring SK
Dermatol Clin 2002 Apr;20(2):249-66. doi: 10.1016/s0733-8635(01)00003-1. PMID: 12120439

Clinical prediction guides

Diagnosis and Treatment of Sexually Transmitted Infections: A Review.
Tuddenham S, Hamill MM, Ghanem KG
JAMA 2022 Jan 11;327(2):161-172. doi: 10.1001/jama.2021.23487. PMID: 35015033
Pathogenesis and virulence of herpes simplex virus.
Zhu S, Viejo-Borbolla A
Virulence 2021 Dec;12(1):2670-2702. doi: 10.1080/21505594.2021.1982373. PMID: 34676800Free PMC Article
Herpes simplex virus: global infection prevalence and incidence estimates, 2016.
James C, Harfouche M, Welton NJ, Turner KM, Abu-Raddad LJ, Gottlieb SL, Looker KJ
Bull World Health Organ 2020 May 1;98(5):315-329. Epub 2020 Mar 25 doi: 10.2471/BLT.19.237149. PMID: 32514197Free PMC Article
Diagnosis and management of undifferentiated fever in children.
Long SS
J Infect 2016 Jul 5;72 Suppl:S68-76. Epub 2016 May 18 doi: 10.1016/j.jinf.2016.04.025. PMID: 27209095
Mathematical models of viral latency.
Selinger C, Katze MG
Curr Opin Virol 2013 Aug;3(4):402-7. Epub 2013 Jul 26 doi: 10.1016/j.coviro.2013.06.015. PMID: 23896280

Recent systematic reviews

Herpesviruses reactivation following COVID-19 vaccination: a systematic review and meta-analysis.
Shafiee A, Amini MJ, Arabzadeh Bahri R, Jafarabady K, Salehi SA, Hajishah H, Mozhgani SH
Eur J Med Res 2023 Aug 10;28(1):278. doi: 10.1186/s40001-023-01238-9. PMID: 37559096Free PMC Article
Herpes simplex virus: global infection prevalence and incidence estimates, 2016.
James C, Harfouche M, Welton NJ, Turner KM, Abu-Raddad LJ, Gottlieb SL, Looker KJ
Bull World Health Organ 2020 May 1;98(5):315-329. Epub 2020 Mar 25 doi: 10.2471/BLT.19.237149. PMID: 32514197Free PMC Article
Herpes Virus, Oral Clinical Signs and QoL: Systematic Review of Recent Data.
Crimi S, Fiorillo L, Bianchi A, D'Amico C, Amoroso G, Gorassini F, Mastroieni R, Marino S, Scoglio C, Catalano F, Campagna P, Bocchieri S, De Stefano R, Fiorillo MT, Cicciù M
Viruses 2019 May 21;11(5) doi: 10.3390/v11050463. PMID: 31117264Free PMC Article
School-based interventions for preventing HIV, sexually transmitted infections, and pregnancy in adolescents.
Mason-Jones AJ, Sinclair D, Mathews C, Kagee A, Hillman A, Lombard C
Cochrane Database Syst Rev 2016 Nov 8;11(11):CD006417. doi: 10.1002/14651858.CD006417.pub3. PMID: 27824221Free PMC Article
Genital herpes.
Hollier LM, Straub H
BMJ Clin Evid 2011 Apr 15;2011 PMID: 21496359Free PMC Article

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