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Vulvar Yolk Sac Tumor

MedGen UID:
925530
•Concept ID:
C4287998
•
Neoplastic Process
Synonym: Vulvar Endodermal Sinus Tumor

Definition

A rare yolk sac tumor that arises from the vulva. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVulvar Yolk Sac Tumor

Professional guidelines

PubMed

Conservative treatment for lower gynecological tract malignancies in children and adolescents: the Institut Gustave-Roussy experience.
Gerbaulet AP, Esche BA, Haie CM, Castaigne D, Flamant F, Chassagne D
Int J Radiat Oncol Biol Phys 1989 Sep;17(3):655-8. doi: 10.1016/0360-3016(89)90119-3. PMID: 2777654

Recent clinical studies

Etiology

Vulvar Yolk Sac Tumors Are Somatically Derived SMARCB1 (INI-1)-Deficient Neoplasms.
Kolin DL, Konstantinopoulos PA, Campos SM, Toumi G, Kolahi KA, Gars EJ, Howitt BE
Am J Surg Pathol 2022 Feb 1;46(2):169-178. doi: 10.1097/PAS.0000000000001777. PMID: 34265804

Diagnosis

Vulvar Yolk Sac Tumors Are Somatically Derived SMARCB1 (INI-1)-Deficient Neoplasms.
Kolin DL, Konstantinopoulos PA, Campos SM, Toumi G, Kolahi KA, Gars EJ, Howitt BE
Am J Surg Pathol 2022 Feb 1;46(2):169-178. doi: 10.1097/PAS.0000000000001777. PMID: 34265804
Vulvar yolk sac tumor mixed with embryonal carcinoma in a peri-pubertal girl: a case report.
Yin-Yi Chang C, Wu KH, Lin TY, Chang WC, Lin WC, Hung YC, Yeh LS
Taiwan J Obstet Gynecol 2011 Dec;50(4):503-5. doi: 10.1016/j.tjog.2011.10.018. PMID: 22212325

Prognosis

Vulvar Yolk Sac Tumors Are Somatically Derived SMARCB1 (INI-1)-Deficient Neoplasms.
Kolin DL, Konstantinopoulos PA, Campos SM, Toumi G, Kolahi KA, Gars EJ, Howitt BE
Am J Surg Pathol 2022 Feb 1;46(2):169-178. doi: 10.1097/PAS.0000000000001777. PMID: 34265804
Vulvar yolk sac tumor mixed with embryonal carcinoma in a peri-pubertal girl: a case report.
Yin-Yi Chang C, Wu KH, Lin TY, Chang WC, Lin WC, Hung YC, Yeh LS
Taiwan J Obstet Gynecol 2011 Dec;50(4):503-5. doi: 10.1016/j.tjog.2011.10.018. PMID: 22212325

Supplemental Content

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    Practice guidelines

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