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Benign basal cell neoplasm

MedGen UID:: 96885
•Concept ID:: C0474802
•: Neoplastic Process

Synonyms:	benign basal cell neoplasm; Benign basal cell tumor; benign basal cell tumor; benign basal cell tumour
SNOMED CT:	Benign basal cell tumor (252996004)

Monarch Initiative:	MONDO:0020805

Definition

A neoplasm composed of basal cells that remains localized and does not metastasize to other anatomic sites. [from MONDO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVBenign basal cell neoplasm

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Neoplasm
      - Epithelial neoplasm
        Basal cell neoplasm
        Benign basal cell neoplasm
        Basal Cell Adenoma

Professional guidelines

PubMed

S2k guideline: Laser therapy of the skin.

Paasch U, Zidane M, Baron JM, Bund T, Cappius HJ, Drosner M, Feise K, Fischer T, Gauglitz G, Gerber PA, Grunewald S, Herberger K, Jung A, Karsai S, Kautz G, Philipp C, Schädel D, Seitz AT, Nast A
J Dtsch Dermatol Ges 2022 Sep;20(9):1248-1267. Epub 2022 Sep 13 doi: 10.1111/ddg.14879. PMID: 36098675

Special criteria for special locations 2: scalp, mucosal, and milk line.

Hofmann-Wellenhof R
Dermatol Clin 2013 Oct;31(4):625-36, ix. Epub 2013 Aug 23 doi: 10.1016/j.det.2013.07.003. PMID: 24075550

Diagnosis and management of atypical fibroxanthoma.

Farley R, Ratner D
Skinmed 2006 Mar-Apr;5(2):83-6. doi: 10.1111/j.1540-9740.2006.04891.x. PMID: 16603840

See all (78)

Recent clinical studies

Etiology

PRAME Updated: Diagnostic, Prognostic, and Therapeutic Role in Skin Cancer.

Cassalia F, Danese A, Tudurachi I, Federico S, Zambello A, Guidotti A, Franceschin L, Bolzon A, Naldi L, Belloni Fortina A
Int J Mol Sci 2024 Jan 27;25(3) doi: 10.3390/ijms25031582. PMID: 38338862 Free PMC Article

Commonly Misdiagnosed Facial Lesion: Pilomatricoma.

Xin TY, Saniasiaya J, Kulasegarah J, Fan CS
Acta Medica (Hradec Kralove) 2023;66(4):158-160. doi: 10.14712/18059694.2024.11. PMID: 38588394

Cutaneous sebaceous carcinoma.

Wu A, Rajak SN, Huilgol SC, James C, Selva D
Australas J Dermatol 2020 Aug;61(3):e283-e292. Epub 2020 Jan 19 doi: 10.1111/ajd.13234. PMID: 31956994

Cutaneous paraneoplasia.

Ramos-E-Silva M, Carvalho JC, Carneiro SC
Clin Dermatol 2011 Sep-Oct;29(5):541-7. doi: 10.1016/j.clindermatol.2010.09.022. PMID: 21855730

Penile melanosis.

Revuz J, Clerici T
J Am Acad Dermatol 1989 Apr;20(4):567-70. doi: 10.1016/s0190-9622(89)70064-5. PMID: 2715403

See all (734)

Diagnosis

Dermatoscopy of Neoplastic Skin Lesions: Recent Advances, Updates, and Revisions.

Weber P, Tschandl P, Sinz C, Kittler H
Curr Treat Options Oncol 2018 Sep 20;19(11):56. doi: 10.1007/s11864-018-0573-6. PMID: 30238167 Free PMC Article

Histologic Mimics of Basal Cell Carcinoma.

Stanoszek LM, Wang GY, Harms PW
Arch Pathol Lab Med 2017 Nov;141(11):1490-1502. doi: 10.5858/arpa.2017-0222-RA. PMID: 29072946

Enhancing Skin Cancer Diagnosis with Dermoscopy.

Wolner ZJ, Yélamos O, Liopyris K, Rogers T, Marchetti MA, Marghoob AA
Dermatol Clin 2017 Oct;35(4):417-437. Epub 2017 Aug 7 doi: 10.1016/j.det.2017.06.003. PMID: 28886798 Free PMC Article

Bazex syndrome.

Rodrigues IA Jr, Gresta LT, Cruz RC, Carvalho GG, Moreira MH
An Bras Dermatol 2013 Nov-Dec;88(6 Suppl 1):209-11. doi: 10.1590/abd1806-4841.20132488. PMID: 24346922 Free PMC Article

Inverted follicular keratosis.

Azzopardi JG, Laurini R
J Clin Pathol 1975 Jun;28(6):465-71. doi: 10.1136/jcp.28.6.465. PMID: 1141446 Free PMC Article

See all (1394)

Therapy

Case of Pilomatricoma After Coronavirus Disease 2019 Vaccination.

Nakazono M, Kawai M, Mizukami A, Kondoh A, Yamaoka H, Mabuchi T
Tokai J Exp Clin Med 2023 Apr 20;48(1):10-12. PMID: 36999388

When to suspect a non-melanoma skin cancer.

Smith H, Wernham A, Patel A
BMJ 2020 Mar 11;368:m692. doi: 10.1136/bmj.m692. PMID: 32161002

Punch and Scoop Technique for Removing Pilomatricoma.

Maranda EL, Riyaz F, Shwayder T
Pediatr Dermatol 2017 Sep;34(5):622-623. Epub 2017 Aug 7 doi: 10.1111/pde.13215. PMID: 28783214

Estimation of cancer risks from radiotherapy of benign diseases.

Trott KR, Kamprad F
Strahlenther Onkol 2006 Aug;182(8):431-6. doi: 10.1007/s00066-006-1542-8. PMID: 16896588

Sweeney EC, McDermott M
J Clin Pathol 1996 Jan;49(1):81-3. doi: 10.1136/jcp.49.1.81. PMID: 8666693 Free PMC Article

See all (223)

Prognosis

Pilomatrixoma: A Comprehensive Review of the Literature.

Jones CD, Ho W, Robertson BF, Gunn E, Morley S
Am J Dermatopathol 2018 Sep;40(9):631-641. doi: 10.1097/DAD.0000000000001118. PMID: 30119102

Bazex syndrome.

Rodrigues IA Jr, Gresta LT, Cruz RC, Carvalho GG, Moreira MH
An Bras Dermatol 2013 Nov-Dec;88(6 Suppl 1):209-11. doi: 10.1590/abd1806-4841.20132488. PMID: 24346922 Free PMC Article

Nail tumors.

Richert B, Lecerf P, Caucanas M, André J
Clin Dermatol 2013 Sep-Oct;31(5):602-17. doi: 10.1016/j.clindermatol.2013.06.014. PMID: 24079590

Cutaneous paraneoplasia.

Ramos-E-Silva M, Carvalho JC, Carneiro SC
Clin Dermatol 2011 Sep-Oct;29(5):541-7. doi: 10.1016/j.clindermatol.2010.09.022. PMID: 21855730

Penile melanosis.

Revuz J, Clerici T
J Am Acad Dermatol 1989 Apr;20(4):567-70. doi: 10.1016/s0190-9622(89)70064-5. PMID: 2715403

See all (459)

Clinical prediction guides

Dermoscopy of Adnexal Tumors.

Zaballos P, Gómez-Martín I, Martin JM, Bañuls J
Dermatol Clin 2018 Oct;36(4):397-412. Epub 2018 Aug 16 doi: 10.1016/j.det.2018.05.007. PMID: 30201149

Pilomatrixoma: A Comprehensive Review of the Literature.

Jones CD, Ho W, Robertson BF, Gunn E, Morley S
Am J Dermatopathol 2018 Sep;40(9):631-641. doi: 10.1097/DAD.0000000000001118. PMID: 30119102

Malignant pilomatricoma: two new observations and review of the relevant literature.

Allaoui M, Hubert E, Michels JJ
Turk Patoloji Derg 2014;30(1):66-8. doi: 10.5146/tjpath.2013.01205. PMID: 24448707

Sweeney EC, McDermott M
J Clin Pathol 1996 Jan;49(1):81-3. doi: 10.1136/jcp.49.1.81. PMID: 8666693 Free PMC Article

Penile melanosis.

Revuz J, Clerici T
J Am Acad Dermatol 1989 Apr;20(4):567-70. doi: 10.1016/s0190-9622(89)70064-5. PMID: 2715403

See all (685)

Recent systematic reviews

A systematic review of Pilomatrix carcinoma arising from the previous scar site of Pilomatrixoma.

Panda SK, Sahoo PK, Agarwala SK, Houghton TT, Sankar KV, Mohanty P
J Cancer Res Ther 2023 Jul-Sep;19(5):1098-1102. doi: 10.4103/jcrt.jcrt_720_21. PMID: 37787269

Systematic review of benefits and practical challenges for application of Mohs surgery for oral tumors.

Hussain A, Kim EY, Khachemoune A
Arch Dermatol Res 2023 Nov;315(9):2479-2484. Epub 2023 May 12 doi: 10.1007/s00403-023-02632-3. PMID: 37173597

Dermoscopy of cutaneous adnexal tumours: a systematic review of the literature.

Lai M, Muscianese M, Piana S, Chester J, Borsari S, Paolino G, Pellacani G, Longo C, Pampena R
J Eur Acad Dermatol Venereol 2022 Sep;36(9):1524-1540. Epub 2022 May 25 doi: 10.1111/jdv.18210. PMID: 35536546 Free PMC Article

Zebras in Foreskin Dermatopathology: A Review.

Alhatem A, Patel N, Lambert WC, Heller DS
J Low Genit Tract Dis 2019 Jul;23(3):235-240. doi: 10.1097/LGT.0000000000000478. PMID: 31149956

Non-syndromic and syndromic keratocystic odontogenic tumors: systematic review and meta-analysis of recurrences.

Antonoglou GN, Sándor GK, Koidou VP, Papageorgiou SN
J Craniomaxillofac Surg 2014 Oct;42(7):e364-71. Epub 2014 Apr 1 doi: 10.1016/j.jcms.2014.03.020. PMID: 24815763

See all (20)

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Benign basal cell neoplasm

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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