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Lupus vulgaris

MedGen UID:
9821
•Concept ID:
C0024131
•
Disease or Syndrome
Synonym: Lupus Vulgaris
SNOMED CT: LV - Lupus vulgaris (10528009); Tuberculosis lupus exedens (10528009); Tuberculosis luposa cutis (10528009); Lupus vulgaris (10528009); Lupus exedens (10528009); Tuberculosis cutis luposa (10528009)
 
Monarch Initiative: MONDO:0006838

Definition

A form of cutaneous tuberculosis. It is seen predominantly in women and typically involves the nasal mucosa; buccal mucosa; and conjunctival mucosa. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLupus vulgaris

Professional guidelines

PubMed

Cutaneous tuberculosis. Part II: Complications, diagnostic workup, histopathologic features, and treatment.
Kaul S, Jakhar D, Mehta S, Singal A
J Am Acad Dermatol 2023 Dec;89(6):1107-1119. Epub 2022 Feb 8 doi: 10.1016/j.jaad.2021.12.064. PMID: 35149148
Cutaneous tuberculosis overview and current treatment regimens.
van Zyl L, du Plessis J, Viljoen J
Tuberculosis (Edinb) 2015 Dec;95(6):629-638. Epub 2014 Dec 25 doi: 10.1016/j.tube.2014.12.006. PMID: 26616847
Cutaneous tuberculosis: diagnosis and treatment.
Barbagallo J, Tager P, Ingleton R, Hirsch RJ, Weinberg JM
Am J Clin Dermatol 2002;3(5):319-28. doi: 10.2165/00128071-200203050-00004. PMID: 12069638

Recent clinical studies

Etiology

Cutaneous tuberculosis in children.
Sethuraman G, Ramesh V
Pediatr Dermatol 2013 Jan-Feb;30(1):7-16. Epub 2012 Nov 22 doi: 10.1111/j.1525-1470.2012.01794.x. PMID: 23173930
Adalimumab: a review of side effects.
Scheinfeld N
Expert Opin Drug Saf 2005 Jul;4(4):637-41. doi: 10.1517/14740338.4.4.637. PMID: 16011443
Neonatal lupus syndromes.
Buyon JP, Clancy RM
Curr Opin Rheumatol 2003 Sep;15(5):535-41. doi: 10.1097/00002281-200309000-00003. PMID: 12960477
Neonatal lupus.
Brucato A, Cimaz R, Stramba-Badiale M
Clin Rev Allergy Immunol 2002 Dec;23(3):279-99. doi: 10.1385/CRIAI:23:3:279. PMID: 12402413
Neonatal lupus.
Buyon JP
Curr Opin Rheumatol 1996 Sep;8(5):485-90. doi: 10.1097/00002281-199609000-00016. PMID: 8941454

Diagnosis

Cutaneous tuberculosis. Part I: Pathogenesis, classification, and clinical features.
Kaul S, Kaur I, Mehta S, Singal A
J Am Acad Dermatol 2023 Dec;89(6):1091-1103. Epub 2022 Feb 8 doi: 10.1016/j.jaad.2021.12.063. PMID: 35149149
Cutaneous tuberculosis. Part II: Complications, diagnostic workup, histopathologic features, and treatment.
Kaul S, Jakhar D, Mehta S, Singal A
J Am Acad Dermatol 2023 Dec;89(6):1107-1119. Epub 2022 Feb 8 doi: 10.1016/j.jaad.2021.12.064. PMID: 35149148
The history of lupus throughout the ages.
Felten R, Lipsker D, Sibilia J, Chasset F, Arnaud L
J Am Acad Dermatol 2022 Dec;87(6):1361-1369. Epub 2020 May 4 doi: 10.1016/j.jaad.2020.04.150. PMID: 32380218
Autoimmune-mediated congenital heart block.
Wainwright B, Bhan R, Trad C, Cohen R, Saxena A, Buyon J, Izmirly P
Best Pract Res Clin Obstet Gynaecol 2020 Apr;64:41-51. Epub 2019 Oct 8 doi: 10.1016/j.bpobgyn.2019.09.001. PMID: 31685414
Lupus pernio.
James DG
Lupus 1992 May;1(3):129-31. doi: 10.1177/096120339200100302. PMID: 1301972

Therapy

Cutaneous tuberculosis. Part II: Complications, diagnostic workup, histopathologic features, and treatment.
Kaul S, Jakhar D, Mehta S, Singal A
J Am Acad Dermatol 2023 Dec;89(6):1107-1119. Epub 2022 Feb 8 doi: 10.1016/j.jaad.2021.12.064. PMID: 35149148
The history of lupus throughout the ages.
Felten R, Lipsker D, Sibilia J, Chasset F, Arnaud L
J Am Acad Dermatol 2022 Dec;87(6):1361-1369. Epub 2020 May 4 doi: 10.1016/j.jaad.2020.04.150. PMID: 32380218
Cutaneous tuberculosis in children.
Sethuraman G, Ramesh V
Pediatr Dermatol 2013 Jan-Feb;30(1):7-16. Epub 2012 Nov 22 doi: 10.1111/j.1525-1470.2012.01794.x. PMID: 23173930
Adalimumab: a review of side effects.
Scheinfeld N
Expert Opin Drug Saf 2005 Jul;4(4):637-41. doi: 10.1517/14740338.4.4.637. PMID: 16011443
Neonatal lupus.
Buyon JP
Curr Opin Rheumatol 1996 Sep;8(5):485-90. doi: 10.1097/00002281-199609000-00016. PMID: 8941454

Prognosis

Cutaneous tuberculosis in children.
Sethuraman G, Ramesh V
Pediatr Dermatol 2013 Jan-Feb;30(1):7-16. Epub 2012 Nov 22 doi: 10.1111/j.1525-1470.2012.01794.x. PMID: 23173930
Clinical profile of cutaneous tuberculosis in pediatric age.
Kathuria S, Ramesh V
G Ital Dermatol Venereol 2010 Apr;145(2):289-302. PMID: 20467401
Neonatal lupus syndromes.
Buyon JP, Rupel A, Clancy RM
Lupus 2004;13(9):705-12. doi: 10.1191/0961203304lu2008oa. PMID: 15485109
Earlobe dermatitis.
Ozkaya-Bayazit E, Baykal C, Büyükbabani N, Hafiz G
Arch Dermatol 2002 Dec;138(12):1607-12. doi: 10.1001/archderm.138.12.1607. PMID: 12472356
Childhood systemic lupus erythematosus, vasculitis, and rheumatic fever and neonatal lupus.
Pelkonen P
Curr Opin Rheumatol 1995 Sep;7(5):430-6. doi: 10.1097/00002281-199509000-00012. PMID: 8519617

Clinical prediction guides

Autoimmune-mediated congenital heart block.
Wainwright B, Bhan R, Trad C, Cohen R, Saxena A, Buyon J, Izmirly P
Best Pract Res Clin Obstet Gynaecol 2020 Apr;64:41-51. Epub 2019 Oct 8 doi: 10.1016/j.bpobgyn.2019.09.001. PMID: 31685414
Twenty-nine cases of lupus vulgaris.
Sellami K, Boudaya S, Chaabane H, Amouri M, Masmoudi A, Mseddi M, Turki H
Med Mal Infect 2016 Mar;46(2):93-5. Epub 2016 Jan 18 doi: 10.1016/j.medmal.2015.12.007. PMID: 26794085
Cutaneous tuberculosis in children.
Sethuraman G, Ramesh V
Pediatr Dermatol 2013 Jan-Feb;30(1):7-16. Epub 2012 Nov 22 doi: 10.1111/j.1525-1470.2012.01794.x. PMID: 23173930
Neonatal lupus.
Brucato A, Cimaz R, Stramba-Badiale M
Clin Rev Allergy Immunol 2002 Dec;23(3):279-99. doi: 10.1385/CRIAI:23:3:279. PMID: 12402413
Lupus pernio.
James DG
Lupus 1992 May;1(3):129-31. doi: 10.1177/096120339200100302. PMID: 1301972

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