From HPO
Renovascular hypertension- MedGen UID:
- 43786
- •Concept ID:
- C0020545
- •
- Disease or Syndrome
The presence of hypertension related to stenosis of the renal artery.
Angina pectoris- MedGen UID:
- 1929
- •Concept ID:
- C0002962
- •
- Sign or Symptom
Paroxysmal chest pain that occurs with exertion or stress and is related to myocardial ischemia.
Restrictive cardiomyopathy- MedGen UID:
- 40111
- •Concept ID:
- C0007196
- •
- Disease or Syndrome
Restrictive left ventricular physiology is characterized by a pattern of ventricular filling in which increased stiffness of the myocardium causes ventricular pressure to rise precipitously with only small increases in volume, defined as restrictive ventricular physiology in the presence of normal or reduced diastolic volumes (of one or both ventricles), normal or reduced systolic volumes, and normal ventricular wall thickness.
Coronary artery atherosclerosis- MedGen UID:
- 3623
- •Concept ID:
- C0010054
- •
- Disease or Syndrome
Reduction of the diameter of the coronary arteries as the result of an accumulation of atheromatous plaques within the walls of the coronary arteries, which increases the risk of myocardial ischemia.
Congestive heart failure- MedGen UID:
- 9169
- •Concept ID:
- C0018802
- •
- Disease or Syndrome
The presence of an abnormality of cardiac function that is responsible for the failure of the heart to pump blood at a rate that is commensurate with the needs of the tissues or a state in which abnormally elevated filling pressures are required for the heart to do so. Heart failure is frequently related to a defect in myocardial contraction.
Hypertensive disorder- MedGen UID:
- 6969
- •Concept ID:
- C0020538
- •
- Disease or Syndrome
The presence of chronic increased pressure in the systemic arterial system.
Intermittent claudication- MedGen UID:
- 7115
- •Concept ID:
- C0021775
- •
- Disease or Syndrome
Intermittent claudication is a symptom of peripheral arterial occlusive disease. After having walked over a distance which is individually characteristic, the patients experience pain or cramps in the calves, feet or thighs which typically subsides on standing still.
Mitral valve prolapse- MedGen UID:
- 7671
- •Concept ID:
- C0026267
- •
- Disease or Syndrome
One or both of the leaflets (cusps) of the mitral valve bulges back into the left atrium upon contraction of the left ventricle.
Mitral stenosis- MedGen UID:
- 44466
- •Concept ID:
- C0026269
- •
- Disease or Syndrome
An abnormal narrowing of the orifice of the mitral valve.
Stroke disorder- MedGen UID:
- 52522
- •Concept ID:
- C0038454
- •
- Disease or Syndrome
Sudden impairment of blood flow to a part of the brain due to occlusion or rupture of an artery to the brain.
Weak pulse- MedGen UID:
- 68554
- •Concept ID:
- C0232132
- •
- Finding
A diminution in the amplitude (strength) of the pulse such that the examiner has difficulty feeling the pulse.
Accelerated atherosclerosis- MedGen UID:
- 376623
- •Concept ID:
- C1849618
- •
- Finding
Atherosclerosis which occurs in a person with certain risk factors (e.g., SLE, diabetes, smoking, hypertension, hypercholesterolaemia, family history of early heart disease) at an earlier age than would occur in another person without those risk factors.
Gastrointestinal hemorrhage- MedGen UID:
- 8971
- •Concept ID:
- C0017181
- •
- Pathologic Function
Hemorrhage affecting the gastrointestinal tract.
Decreased DLCO- MedGen UID:
- 892993
- •Concept ID:
- C4073175
- •
- Finding
Reduced ability of the lungs to transfer gas from inspired air to the bloodstream as measured by the diffusing capacity of the lungs for carbon monoxide (DLCO) test.
White oral mucosal macule- MedGen UID:
- 1716730
- •Concept ID:
- C5398009
- •
- Finding
A small circumscribed whitish change in the color of the oral mucosa that is neither elevated nor depressed.
Cutis laxa- MedGen UID:
- 8206
- •Concept ID:
- C0010495
- •
- Disease or Syndrome
Wrinkled, redundant, inelastic and sagging skin.
Civatte bodies- MedGen UID:
- 90706
- •Concept ID:
- C0333440
- •
- Anatomical Abnormality
Eosinophilic hyaline ovoid bodies which are often found in the subepidermal papillary regions or sometimes in the epidermis. Civatte bodies (CBs) are seen as rounded, homogenous, eosinophilic masses on routine H and E staining lying in the deeper parts of epidermis/epithelium and more frequently in dermis/connective tissue. They are known as CBs (in epithelium/epidermis), colloid bodies, or hyaline bodies (in connective tissue). They are 10-25 micrometers in diameter and situated mostly within or above the inflammatory cell infiltrate. In lichen planus, the number of necrotic keratinocytes may be so large that they are seen lying in clusters in the uppermost dermis. These bodies show a positive periodic acid Schiff reaction and are diastase resistant
Yellow papule- MedGen UID:
- 1373750
- •Concept ID:
- C2033396
- •
- Finding
A papule with yellow color.
Angioid streaks- MedGen UID:
- 1541
- •Concept ID:
- C0002982
- •
- Disease or Syndrome
Angioid streaks are irregular tapering linear breaks in the Bruch membrane that typically emanate from the optic disk (summary by Karacorlu et al., 2002).
Macular degeneration- MedGen UID:
- 7434
- •Concept ID:
- C0024437
- •
- Disease or Syndrome
A nonspecific term denoting degeneration of the retinal pigment epithelium and/or retinal photoreceptor cells of the macula lutea.
Optic disc drusen- MedGen UID:
- 14495
- •Concept ID:
- C0029128
- •
- Disease or Syndrome
Optic disc drusen are acellular, calcified deposits within the optic nerve head. Optic disc drusen are congenital and developmental anomalies of the optic nerve head, representing hyaline-containing bodies that, over time, appear as elevated, lumpy irregularities on the anterior portion of the optic nerve.
Retinal hemorrhage- MedGen UID:
- 11210
- •Concept ID:
- C0035317
- •
- Pathologic Function
Hemorrhage occurring within the retina.
Reduced visual acuity- MedGen UID:
- 65889
- •Concept ID:
- C0234632
- •
- Finding
Diminished clarity of vision.
Choroidal neovascularization- MedGen UID:
- 154726
- •Concept ID:
- C0600518
- •
- Pathologic Function
Choroidal neovascularization (CNV) is the creation of new blood vessels in the choroid layer of the eye.
Visual impairment- MedGen UID:
- 777085
- •Concept ID:
- C3665347
- •
- Finding
Visual impairment (or vision impairment) is vision loss (of a person) to such a degree as to qualify as an additional support need through a significant limitation of visual capability resulting from either disease, trauma, or congenital or degenerative conditions that cannot be corrected by conventional means, such as refractive correction, medication, or surgery.
Retinal peau d'orange- MedGen UID:
- 1713761
- •Concept ID:
- C5398025
- •
- Finding
A pebbly orange appearance of the fundus that is said to resemble the skin of an orange.
- Abnormality of head or neck
- Abnormality of the cardiovascular system
- Abnormality of the digestive system
- Abnormality of the eye
- Abnormality of the genitourinary system
- Abnormality of the integument
- Abnormality of the respiratory system