LOCUS NM_001033860 3573 bp mRNA linear ROD 29-JUL-2024
DEFINITION Rattus norvegicus CEA cell adhesion molecule 1 (Ceacam1),
transcript variant 1, mRNA.
ACCESSION NM_001033860
VERSION NM_001033860.1
KEYWORDS RefSeq; RefSeq Select.
SOURCE Rattus norvegicus (Norway rat)
ORGANISM Rattus norvegicus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
REFERENCE 1 (bases 1 to 3573)
AUTHORS Huff,L.P., Kikuchi,D.S., Faidley,E., Forrester,S.J., Tsai,M.Z.,
Lassegue,B. and Griendling,K.K.
TITLE Polymerase-delta-interacting protein 2 activates the RhoGEF
epithelial cell transforming sequence 2 in vascular smooth muscle
cells
JOURNAL Am J Physiol Cell Physiol 316 (5), C621-C631 (2019)
PUBMED 30726115
REFERENCE 2 (bases 1 to 3573)
AUTHORS Bonsor,D.A., Gunther,S., Beadenkopf,R., Beckett,D. and
Sundberg,E.J.
TITLE Diverse oligomeric states of CEACAM IgV domains
JOURNAL Proc Natl Acad Sci U S A 112 (44), 13561-13566 (2015)
PUBMED 26483485
REFERENCE 3 (bases 1 to 3573)
AUTHORS Huang,Y.H., Zhu,C., Kondo,Y., Anderson,A.C., Gandhi,A., Russell,A.,
Dougan,S.K., Petersen,B.S., Melum,E., Pertel,T., Clayton,K.L.,
Raab,M., Chen,Q., Beauchemin,N., Yazaki,P.J., Pyzik,M.,
Ostrowski,M.A., Glickman,J.N., Rudd,C.E., Ploegh,H.L., Franke,A.,
Petsko,G.A., Kuchroo,V.K. and Blumberg,R.S.
TITLE CEACAM1 regulates TIM-3-mediated tolerance and exhaustion
JOURNAL Nature 517 (7534), 386-390 (2015)
PUBMED 25363763
REMARK Erratum:[Nature. 2016 Aug 18;536(7616):359. doi:
10.1038/nature17421. PMID: 26982724]
REFERENCE 4 (bases 1 to 3573)
AUTHORS Heckt,T., Bickert,T., Jeschke,A., Seitz,S., Schulze,J., Ito,W.D.,
Zimmermann,W., Amling,M., Schinke,T., Horst,A.K. and Keller,J.
TITLE Increased osteoclastogenesis in mice lacking the carcinoembryonic
antigen-related cell adhesion molecule 1
JOURNAL PLoS One 9 (12), e114360 (2014)
PUBMED 25490771
REMARK Publication Status: Online-Only
REFERENCE 5 (bases 1 to 3573)
AUTHORS Singer,B.B., Opp,L., Heinrich,A., Schreiber,F.,
Binding-Liermann,R., Berrocal-Almanza,L.C., Heyl,K.A., Muller,M.M.,
Weimann,A., Zweigner,J. and Slevogt,H.
TITLE Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered
immune responses
JOURNAL PLoS One 9 (4), e94106 (2014)
PUBMED 24743304
REMARK GeneRIF: CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered
immune responses
Publication Status: Online-Only
REFERENCE 6 (bases 1 to 3573)
AUTHORS Culic,O., Huang,Q.H., Flanagan,D., Hixson,D. and Lin,S.H.
TITLE Molecular cloning and expression of a new rat liver cell-CAM105
isoform. Differential phosphorylation of isoforms
JOURNAL Biochem J 285 (Pt 1) (Pt 1), 47-53 (1992)
PUBMED 1637321
REFERENCE 7 (bases 1 to 3573)
AUTHORS McCuaig,K., Turbide,C. and Beauchemin,N.
TITLE mmCGM1a: a mouse carcinoembryonic antigen gene family member,
generated by alternative splicing, functions as an adhesion
molecule
JOURNAL Cell Growth Differ 3 (3), 165-174 (1992)
PUBMED 1633107
REFERENCE 8 (bases 1 to 3573)
AUTHORS Dveksler,G.S., Pensiero,M.N., Cardellichio,C.B., Williams,R.K.,
Jiang,G.S., Holmes,K.V. and Dieffenbach,C.W.
TITLE Cloning of the mouse hepatitis virus (MHV) receptor: expression in
human and hamster cell lines confers susceptibility to MHV
JOURNAL J Virol 65 (12), 6881-6891 (1991)
PUBMED 1719235
REFERENCE 9 (bases 1 to 3573)
AUTHORS Lin,S.H., Culic,O., Flanagan,D. and Hixson,D.C.
TITLE Immunochemical characterization of two isoforms of rat liver
ecto-ATPase that show an immunological and structural identity with
a glycoprotein cell-adhesion molecule with Mr 105,000
JOURNAL Biochem J 278 (Pt 1) (Pt 1), 155-161 (1991)
PUBMED 1831973
REFERENCE 10 (bases 1 to 3573)
AUTHORS Williams,R.K., Jiang,G.S. and Holmes,K.V.
TITLE Receptor for mouse hepatitis virus is a member of the
carcinoembryonic antigen family of glycoproteins
JOURNAL Proc Natl Acad Sci U S A 88 (13), 5533-5536 (1991)
PUBMED 1648219
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
M92848.1, J04963.1, BC061740.1 and JAXUCZ010000001.1.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC061740.1, J04963.1 [ECO:0000332]
RNAseq introns :: mixed sample support SAMN16676784,
SAMN16676785 [ECO:0006172]
##Evidence-Data-END##
##RefSeq-Attributes-START##
RefSeq Select criteria :: based on expression, longest protein
##RefSeq-Attributes-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-29 M92848.1 1-29
30-1655 J04963.1 37-1662
1656-1723 BC061740.1 1642-1709
1724-1873 J04963.1 1726-1875
1874-2178 BC061740.1 1848-2152
2179-3573 JAXUCZ010000001.1 90171401-90172795 c
FEATURES Location/Qualifiers
source 1..3573
/organism="Rattus norvegicus"
/mol_type="mRNA"
/strain="BN"
/db_xref="taxon:10116"
/chromosome="1"
/map="1q21"
gene 1..3573
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="CEA cell adhesion molecule 1"
/db_xref="GeneID:81613"
/db_xref="RGD:67396"
exon 1..121
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/inference="alignment:Splign:2.1.0"
misc_feature 40..42
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="upstream in-frame stop codon"
CDS 58..1617
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="isoform 1 precursor is encoded by transcript
variant 1; GP110; pp120; C-CAM 105; ecto-ATPase; cell-CAM
105; ATP-dependent taurocolate-carrier protein; bone
gamma-carboxyglutamic acid (Gla) protein; osteocalcin;
CEA-related cell adhesion molecule 1 (bone
gamma-carboxyglutamic acid (Gla) protein) (osteocalcin);
carcinoembryonic antigen-related cell adhesion molecule 1
(biliary glycoprotein); pp120/ecto-ATPase;
carcinoembryonic antigen related cell adhesion molecule 1"
/codon_start=1
/product="carcinoembryonic antigen-related cell adhesion
molecule 1 isoform 1 precursor"
/protein_id="NP_001029032.1"
/db_xref="GeneID:81613"
/db_xref="RGD:67396"
/translation="MELASARLLRGQIPWRGLLLTASLLTYWSPLTTAQVTVDAVPPN
VVEEKSVLLLAHNLPQEFQVFYWYKGTTLNPDSEIARYIRSDNMSKTGPAYSGRETIY
SNGSLFFQNVNKTDERAYTLSVFDQQFNPIQTSVQFRVYPALQKPNVTGNNSNPMEGE
PFVSLMCEPYTNNTSYLWSRNGESLSEGDRVTFSEGNRTLTLLNVRRTDKGYYECEAR
NPATFNRSDPFNLDVIYGPDAPVISPPDIYLHQGSNLNLSCHADSNPPAQYFWLINEK
LQTSSQELFISNITTNNSGTYACFVNNTVTGLSRTTVKNITVFEPVTQPSIQITNTTV
KELGSVTLTCFSKDTGVSVRWLFNSQSLQLTDRMTLSQDNSTLRIDPIKREDAGDYQC
EISNPVSFRISHPIKLDVIPDPTQGNSGLSEGAIAGIVIGSVAGVALIAALAYFLYSR
KTGGGSDHRDLTEHKPSTSSHNLGPSDDSPNKVDDVSYSVLNFNAQQSKRPTSASSSP
TETVYSVVKKK"
sig_peptide 58..159
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/inference="COORDINATES: ab initio prediction:SignalP:6.0"
mat_peptide 160..1614
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/product="Carcinoembryonic antigen-related cell adhesion
molecule 1. /id=PRO_0000014564"
/note="propagated from UniProtKB/Swiss-Prot (P16573.4)"
misc_feature 160..162
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="Pyrrolidone carboxylic acid.
/evidence=ECO:0000250|UniProtKB:P13688; propagated from
UniProtKB/Swiss-Prot (P16573.4);
pyrrolidone-carboxylic-acid site"
misc_feature 172..483
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="propagated from UniProtKB/Swiss-Prot (P16573.4);
Region: Required for homophilic binding.
/evidence=ECO:0000269|PubMed:8831574"
misc_feature 316..318
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (P16573.4); glycosylation site"
misc_feature 367..369
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (P16573.4); glycosylation site"
misc_feature 394..396
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (P16573.4); glycosylation site"
misc_feature 499..501
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (P16573.4); glycosylation site"
misc_feature 511..513
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (P16573.4); glycosylation site"
misc_feature 574..576
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (P16573.4); glycosylation site"
misc_feature 646..648
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (P16573.4); glycosylation site"
misc_feature 727..729
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (P16573.4); glycosylation site"
misc_feature 823..825
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (P16573.4); glycosylation site"
misc_feature 919..921
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (P16573.4); glycosylation site"
misc_feature 931..933
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (P16573.4); glycosylation site"
misc_feature 961..963
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (P16573.4); glycosylation site"
misc_feature 1000..1002
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (P16573.4); glycosylation site"
misc_feature 1048..1050
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="N-linked (GlcNAc...) asparagine.
/evidence=ECO:0000255|PROSITE-ProRule:PRU00498; propagated
from UniProtKB/Swiss-Prot (P16573.4); glycosylation site"
misc_feature 1177..1179
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="N-linked (GlcNAc...) asparagine, atypical.
/evidence=ECO:0000250|UniProtKB:P31809,
ECO:0000255|PROSITE-ProRule:PRU00498; propagated from
UniProtKB/Swiss-Prot (P16573.4); glycosylation site"
misc_feature 1333..1395
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="propagated from UniProtKB/Swiss-Prot (P16573.4);
transmembrane region"
misc_feature 1390..1428
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="propagated from UniProtKB/Swiss-Prot (P16573.4);
Region: Interaction with calmodulin.
/evidence=ECO:0000269|PubMed:8576129"
misc_feature 1396..1614
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="propagated from UniProtKB/Swiss-Prot (P16573.4);
Region: Interaction with FLNA.
/evidence=ECO:0000269|PubMed:16291724"
misc_feature 1420..1614
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="propagated from UniProtKB/Swiss-Prot (P16573.4);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 1507..1614
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="propagated from UniProtKB/Swiss-Prot (P16573.4);
Region: Required for interaction with PTPN11 and PTPN6 and
for control of phosphorylation level.
/evidence=ECO:0000250|UniProtKB:P31809"
misc_feature 1519..1521
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="Phosphotyrosine, by SRC, LCK, INSR and EGFR.
/evidence=ECO:0000269|PubMed:15467833,
ECO:0000269|PubMed:16054098, ECO:0000269|PubMed:7518458,
ECO:0000269|PubMed:7626603, ECO:0000269|PubMed:9712832;
propagated from UniProtKB/Swiss-Prot (P16573.4);
phosphorylation site"
misc_feature 1564..1566
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="Phosphoserine.
/evidence=ECO:0000269|PubMed:16054098,
ECO:0000269|PubMed:7518458; propagated from
UniProtKB/Swiss-Prot (P16573.4); phosphorylation site"
misc_feature 1594..1605
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="propagated from UniProtKB/Swiss-Prot (P16573.4);
Region: Essential for interaction with PTPN11 and PTPN6.
/evidence=ECO:0000250|UniProtKB:P31809"
misc_feature 1594..1596
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/note="Phosphotyrosine, by INSR, SRC and LCK.
/evidence=ECO:0000269|PubMed:16054098; propagated from
UniProtKB/Swiss-Prot (P16573.4); phosphorylation site"
exon 122..481
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/inference="alignment:Splign:2.1.0"
exon 482..760
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/inference="alignment:Splign:2.1.0"
exon 761..1015
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/inference="alignment:Splign:2.1.0"
exon 1016..1291
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/inference="alignment:Splign:2.1.0"
exon 1292..1418
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/inference="alignment:Splign:2.1.0"
exon 1419..1471
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/inference="alignment:Splign:2.1.0"
exon 1472..1503
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/inference="alignment:Splign:2.1.0"
exon 1504..3573
/gene="Ceacam1"
/gene_synonym="Bgp; BGPR; Ccam1; CD66a"
/inference="alignment:Splign:2.1.0"
ORIGIN
1 agccgtgttg gagccaaatc tcttccccag agaagaacct agcaggcagc agagactatg
61 gagctagcct cggctcgtct cctcagaggg cagattccct ggaggggact actgctcaca
121 gcctcacttt taacctactg gagccctctc accactgccc aagtcaccgt agacgctgtg
181 ccacccaacg ttgttgagga gaagagcgtt cttttactcg ctcacaatct gccgcaggag
241 ttccaagtct tttactggta caagggaacc actttgaatc cagacagtga aattgcacga
301 tatataagat ccgataatat gagtaaaaca ggacctgcat acagcggcag agagacaata
361 tacagcaatg gatccttgtt cttccaaaat gtcaacaaga ctgacgagag agcctacaca
421 ctatctgtgt ttgatcaaca atttaatcct atacaaacgt ctgtgcaatt tcgtgtatac
481 cccgcattac aaaagcccaa cgtcacaggt aacaactcca atcccatgga gggtgagccc
541 ttcgtatcat taatgtgtga accgtacact aacaatacca gctacctgtg gagcagaaat
601 ggtgaaagcc tctcagaagg tgacagggtg acgttctctg agggcaacag gactctcact
661 ttactcaacg tcaggaggac tgacaaagga tactatgagt gtgaagcccg gaacccagcg
721 actttcaatc gaagtgaccc attcaacctg gacgttatct atggtccgga cgccccagtt
781 atatcccctc cagatattta tttgcatcaa gggtcaaacc tcaacctctc ctgccatgca
841 gactctaacc ctcccgcaca gtacttttgg cttatcaatg agaagctcca gacatcctcc
901 caagagctct ttatctccaa catcactact aacaatagcg gaacctatgc ctgcttcgtc
961 aataacactg tcactggcct cagtcgcacc acagtcaaga acattacagt ctttgagcca
1021 gtgactcagc cctccatcca aatcaccaac accacagtca aagaactagg ctctgtgacc
1081 ctgacctgct tctcaaagga cactggagtc tccgtccgat ggcttttcaa tagccagagt
1141 ctgcagctca cagacaggat gacgctctcc caggacaaca gcaccctcag aatagaccct
1201 attaagagag aagatgccgg ggactatcag tgtgagatct ccaacccggt cagtttcagg
1261 ataagtcacc caatcaagct ggacgtaata cctgatccaa cacaaggaaa ttctggcctc
1321 tcagagggtg ccattgcagg cattgtgatt ggatctgtgg ctggagtggc cctaatagca
1381 gcgctggcat acttccttta ttccaggaag actggcgggg gaagtgacca tcgagatctc
1441 acagagcaca aaccctcaac ctccagccac aatctgggtc cttctgacga ctctcctaac
1501 aaggtggatg acgtctcata ctctgtcctg aacttcaatg cccagcaatc caaacgacca
1561 acttcagcct cttcaagccc cacagaaaca gtttattcgg tagtcaaaaa gaagtgacat
1621 tgtctgtcct gctgactgca ccagtgatgc attcccagat tctctccctc acgggagagt
1681 ccctgcacac acgcgcacgt gcgcgtgcac acacacacac acacacacac acatgcacac
1741 acacacgcac acacgcacgc acacacacac atgcacacac gcacacacac atgtatacac
1801 tctattgact ccttccgtgt taatagaaga aaaggtgtat cctggagcct acagaaaacc
1861 caaccctttc taggcattaa aatttggccg agagagagga accaaaacgg cccacccctt
1921 cacttttctg ttttaaattg atgtattctg agcacattca ctcctccacc caactccaag
1981 tcctgccctg tcagagtctg acttgaattt cgataaacct cggaggtcac ctaagtgctt
2041 atgccaaaaa ccacaaaacc aaacaaagca aaacagaagc aggaaatggc cgatcccatg
2101 tcttaaggct gatgcgaagc caccacacat gaagatcaaa gccataggca ttcgttcgct
2161 gggcagtccg cacaccagcc aactgtcaca tttactgtga cattagagtc tctgaaccat
2221 gggtcttcac gcctgagccc ttctccagga aacccactca gagcaactag agaaacccct
2281 tggcagcaaa caccagcaat tgctaagcag ggtgcagaag aaaagacgac atttctcaca
2341 tctaccagga tggcgcccag gaaagcaggg ctggcggttt tggactgaga gacatatgga
2401 atttgaaaag ggaacagaga gatacccttt gaggagtgtc gaaattattt taaaagaagc
2461 catatttgga ggcgttggaa ttttcctctt cctaagacaa tccactattt gacatttgta
2521 gctgctgact ttcctttcgc tgggcgagct gatcagtttg ccttagggca actaaatctc
2581 acgtctccct tggccccccg cacgcaagcc ctttggatcg tgagctccaa accaaaaata
2641 aataagtgaa tcgtgaggcg gtcccttgca gaaccactgt catgggtcag gctcctactt
2701 ttctgtatta gtcaagaaaa gcctgagttt tcctttctcg tttttatcct gtcgttctgg
2761 ccacagcccg gacagtcttc ctctgagatc tctagcttgt ctaccttctt gtgtttcttt
2821 taaactctca cgaaactgct taacttcaaa aagtaaaata ataactttcc tcatctacac
2881 cagaaagaga cccaactccg tttctggaaa cctaggatca gcctccagct gccctctgaa
2941 ctttctgcct tgtttcccct ttcttttgac tctaatacct catgcagtgt cctacctgtt
3001 aggatgacag cacaggccac taggcctggc cacccgtaca ttctgtctgc cctgcactct
3061 caggaaacct tggcctctgt ctgtttggtt catgtgaagt gtgcccttaa aggaacagtc
3121 actcataccg gaggcattgt ttacagcctg gaacattcta cacagtgcat cactggaaat
3181 gggctgctag cagggttctc gtacccagcc atggcctttc tgtagcctcg gaaacctgcc
3241 tttccaccag ggatgagtcc cagcagcgga gaaaaggcaa atgtagtctc aggaacccgc
3301 tgttcaaagg cacaccctct gtgcctgtta accaaaggtt gtatttgata tcgagtattt
3361 ggtctcatgc catgcctaac aggcttctga gagaattgtt tagttctccc actcagggat
3421 ttctttcagg gatttccagc cctaacatga cctgtgtata ttttgcttca cccacgcaat
3481 gctgggttac ttcattttgc ccggctaaag ccaaatcgga gttatttgta aatttgctct
3541 atgttcataa taaaaattta tatatcactg ata
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