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Drosophila melanogaster Ankyrin-repeat, SH3-domain, and Proline-rich-region containing protein, transcript variant A (ASPP), mRNA

NCBI Reference Sequence: NM_137721.3

FASTA Graphics 

LOCUS       NM_137721               4600 bp    mRNA    linear   INV 26-DEC-2023
DEFINITION  Drosophila melanogaster Ankyrin-repeat, SH3-domain, and
            Proline-rich-region containing protein, transcript variant A
            (ASPP), mRNA.
ACCESSION   NM_137721
VERSION     NM_137721.3
DBLINK      BioProject: PRJNA164
            BioSample: SAMN02803731
KEYWORDS    RefSeq.
SOURCE      Drosophila melanogaster (fruit fly)
  ORGANISM  Drosophila melanogaster
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
REFERENCE   1  (bases 1 to 4600)
  AUTHORS   Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St
            Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K.,
            Strelets,V., Russo,S.M. and Gelbart,W.M.
  CONSRTM   FlyBase Consortium
  TITLE     Gene Model Annotations for Drosophila melanogaster: Impact of
            High-Throughput Data
  JOURNAL   G3 (Bethesda) 5 (8), 1721-1736 (2015)
   PUBMED   26109357
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4600)
  AUTHORS   Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St
            Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B.,
            Russo,S.M. and Gelbart,W.M.
  CONSRTM   FlyBase Consortium
  TITLE     Gene Model Annotations for Drosophila melanogaster: The
            Rule-Benders
  JOURNAL   G3 (Bethesda) 5 (8), 1737-1749 (2015)
   PUBMED   26109356
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4600)
  AUTHORS   Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I.,
            Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R.,
            Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G.,
            Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N.,
            Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A.,
            Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E.
  TITLE     The Release 6 reference sequence of the Drosophila melanogaster
            genome
  JOURNAL   Genome Res 25 (3), 445-458 (2015)
   PUBMED   25589440
REFERENCE   4  (bases 1 to 4600)
  AUTHORS   Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M.,
            Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F.,
            Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E.
  TITLE     Sequence finishing and mapping of Drosophila melanogaster
            heterochromatin
  JOURNAL   Science 316 (5831), 1625-1628 (2007)
   PUBMED   17569867
REFERENCE   5  (bases 1 to 4600)
  AUTHORS   Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
  TITLE     The Release 5.1 annotation of Drosophila melanogaster
            heterochromatin
  JOURNAL   Science 316 (5831), 1586-1591 (2007)
   PUBMED   17569856
  REMARK    Erratum:[Science. 2007 Sep 7;317(5843):1325]
REFERENCE   6  (bases 1 to 4600)
  AUTHORS   Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D.,
            Ashburner,M. and Anxolabehere,D.
  TITLE     Combined evidence annotation of transposable elements in genome
            sequences
  JOURNAL   PLoS Comput Biol 1 (2), 166-175 (2005)
   PUBMED   16110336
REFERENCE   7  (bases 1 to 4600)
  AUTHORS   Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A.,
            Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A.,
            Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W.,
            Celniker,S.E., Rubin,G.M. and Karpen,G.H.
  TITLE     Heterochromatic sequences in a Drosophila whole-genome shotgun
            assembly
  JOURNAL   Genome Biol 3 (12), RESEARCH0085 (2002)
   PUBMED   12537574
REFERENCE   8  (bases 1 to 4600)
  AUTHORS   Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J.,
            Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E.,
            Rubin,G.M., Ashburner,M. and Celniker,S.E.
  TITLE     The transposable elements of the Drosophila melanogaster
            euchromatin: a genomics perspective
  JOURNAL   Genome Biol 3 (12), RESEARCH0084 (2002)
   PUBMED   12537573
REFERENCE   9  (bases 1 to 4600)
  AUTHORS   Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S.,
            Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E.,
            Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L.,
            Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D.,
            Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J.,
            Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M.,
            Rubin,G.M. and Lewis,S.E.
  TITLE     Annotation of the Drosophila melanogaster euchromatic genome: a
            systematic review
  JOURNAL   Genome Biol 3 (12), RESEARCH0083 (2002)
   PUBMED   12537572
REFERENCE   10 (bases 1 to 4600)
  AUTHORS   Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W.,
            Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E.,
            Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M.,
            Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S.,
            Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M.,
            Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W.,
            Gibbs,R.A. and Rubin,G.M.
  TITLE     Finishing a whole-genome shotgun: release 3 of the Drosophila
            melanogaster euchromatic genome sequence
  JOURNAL   Genome Biol 3 (12), RESEARCH0079 (2002)
   PUBMED   12537568
REFERENCE   11 (bases 1 to 4600)
  AUTHORS   Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D.,
            Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F.,
            George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N.,
            Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X.,
            Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D.,
            Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L.,
            Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D.,
            Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M.,
            Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S.,
            Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P.,
            Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A.,
            Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B.,
            Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I.,
            Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S.,
            Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C.,
            Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S.,
            Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z.,
            Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J.,
            Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J.,
            Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z.,
            Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C.,
            Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A.,
            Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C.,
            McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C.,
            Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L.,
            Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K.,
            Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S.,
            Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K.,
            Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I.,
            Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C.,
            Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R.,
            Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A.,
            Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT,
            Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F.,
            Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H.,
            Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O.,
            Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C.
  TITLE     The genome sequence of Drosophila melanogaster
  JOURNAL   Science 287 (5461), 2185-2195 (2000)
   PUBMED   10731132
REFERENCE   12 (bases 1 to 4600)
  AUTHORS   Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R.,
            Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R.,
            Smith,E., Yu,C. and Rubin,G.
  CONSRTM   Berkeley Drosophila Genome Project
  TITLE     Drosophila melanogaster release 4 sequence
  JOURNAL   Unpublished
REFERENCE   13 (bases 1 to 4600)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-DEC-2023) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   14 (bases 1 to 4600)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (13-DEC-2023) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   15 (bases 1 to 4600)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2022) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   16 (bases 1 to 4600)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2020) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   17 (bases 1 to 4600)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (22-APR-2019) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   18 (bases 1 to 4600)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAY-2018) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   19 (bases 1 to 4600)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (07-DEC-2016) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   20 (bases 1 to 4600)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2015) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   21 (bases 1 to 4600)
  AUTHORS   Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R.,
            Park,S., Svirskas,R. and Karpen,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
            Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne
            Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA
  REMARK    Direct Submission
REFERENCE   22 (bases 1 to 4600)
  AUTHORS   Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S.,
            Svirskas,R. and Rubin,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
            Lawrence Berkeley National Laboratory, One Cyclotron Road, MS
            64-121, Berkeley, CA 94720, USA
  REMARK    Direct Submission
REFERENCE   23 (bases 1 to 4600)
  AUTHORS   Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
  CONSRTM   Drosophila Heterochromatin Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project,
            Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron
            Road, Mailstop 64-121, Berkeley, CA 94720, USA
REFERENCE   24 (bases 1 to 4600)
  AUTHORS   Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive,
            Rockville, MD 20850, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by FlyBase. This
            record is derived from an annotated genomic sequence (NT_033778).
            
            On Jul 15, 2014 this sequence version replaced NM_137721.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: FlyBase
            Annotation Status   :: Full annotation
            Annotation Version  :: Release 6.54
            URL                 :: http://flybase.org
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4600
                     /organism="Drosophila melanogaster"
                     /mol_type="mRNA"
                     /db_xref="taxon:7227"
                     /chromosome="2R"
                     /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2]
                     bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]"
     gene            1..4600
                     /gene="ASPP"
                     /locus_tag="Dmel_CG18375"
                     /gene_synonym="CG18375; dASPP; Dmel\CG18375"
                     /note="Ankyrin-repeat, SH3-domain, and Proline-rich-region
                     containing Protein"
                     /map="57D2-57D4"
                     /db_xref="FLYBASE:FBgn0034606"
                     /db_xref="GeneID:37422"
     CDS             444..3506
                     /gene="ASPP"
                     /locus_tag="Dmel_CG18375"
                     /gene_synonym="CG18375; dASPP; Dmel\CG18375"
                     /note="CG18375 gene product from transcript CG18375-RA;
                     CG18375-PA; ASPP-PA; Ankyrin-repeat, SH3-domain and
                     Proline-rich-region containing protein"
                     /codon_start=1
                     /product="Ankyrin-repeat, SH3-domain, and
                     Proline-rich-region containing protein, isoform A"
                     /protein_id="NP_611565.2"
                     /db_xref="FLYBASE:FBpp0071548"
                     /db_xref="GeneID:37422"
                     /db_xref="FLYBASE:FBgn0034606"
                     /translation="MKEPTNTLDEIVPSRLTSAELRAMALRQQQQIDSQHQLLATKEQ
                     RLRFLKSQEVRSAVASAEGERLRRLRERVEAQESKLRRLRALRGQVDLQKTYNVTLSN
                     DLDSIRALFSEKEKELSLAVAKVEALTRQLEELRRDRRCPVNILTAAGNGVGGQSLPP
                     QASRELEKLRRELMYRNQLSLQQDARLHMQREALQQRQAELRSTDQRIYELQTRLQRK
                     KQANTHHQQQQQQQQQHQQQQHQQQHQQTTVQQQQQQQQQLHVQSAQLLAAAAAATAQ
                     QQQQHQQHQQQQQQQQQQSASNLGKHGGVAALKQQLLQKQVNQLAAAAAAAAAGRARG
                     NVAAVEPFIHTPQKSTITSTASYLSGGMKHAAATANTNQQNQLIQDLTHVKLGQNSGF
                     FAGSVPVPVASSSCESDESKLAKKLLAAPAKTEAELRKQAQTEAMDSTTHIYAEVGPK
                     KRDREAAAAAAAAAAAAAAAAQAAAEAANQAATAAAASAISPPATANASKIPKSTTSS
                     SSSASALISKLNQQATAKESQDQQQSQAKKNEISVTSETLSERNTQQQLTVHSMPLGA
                     ISKSVALAVSNASKPLQVQVSNVAVPPRKPISSVAPNSVSSGSSIPKMITYSPKVNRV
                     APNVVMTDPRPALPPKPSKMSPTEQPSPVEANTSGSAGGAGSGAASASTANKTQTATF
                     GLQSLNINDNLPIKAKPLTIRKQPLFEQPRLKSSQSSSNGQQKPPLLQLQNQRKSEPS
                     ARQPTENLPDTSPQHSPSSESSADETDRMVAPSITTSQQETSTSATSTTTTVTTSNIK
                     ERTGNGKPKLGRRVSFDPLALLLDASLEGELELVKKTAMQVANPSAANDEGITALHNA
                     ICAGHIDIVKFLVEFGCDVNAQDSDGWTPLHCAASCNNLSMVKFLVESGACLFASTLS
                     DHETPAEKCEEDEEGFDGCSEYLYSIQEKLGILHNGDVYAVFSYEAQNGDELSFHVNE
                     PLIVLRKGDDAENEWWWARNAAGEEGYVPRNLLGLYPRVPPHSPHFSD"
ORIGIN      
        1 tcagttgctc aacgcgctta cctgtcgata gacgtgtttt ccccgaaaaa ggaaaagccg
       61 cgtgctccgt ctcgctcgct cgctcattct gcgcgtgtgt gtgtctgtga gattgtctgc
      121 tctttacgag cacgtaagtg agtgtgagtg tgtatattca attaattaca aagtcaggaa
      181 agaagcagct atgtgaattg aatgaaagaa agccagttaa aaagtatgca aaaaagttgc
      241 ctgatataaa aggcagggtg aagaaaggcg aagaagaagc ggcagtgtaa atggtgatta
      301 attcacttta aggtgcaatt aaacagcagc gaaataagca acaacaaaac agcagcaaaa
      361 gcagcagcaa caacagaaga agaagcagca acaacagcag cgcaaggtgc agacaagatt
      421 ggatgaatct ctaacgtcat ggtatgaagg agccgacgaa cactttggat gaaattgtgc
      481 ccagcaggct gacgtcagcc gaactgaggg cgatggcatt gagacagcag cagcaaatcg
      541 acagccagca ccagctgctg gccaccaagg agcagcgcct gcgcttcctc aagtcgcagg
      601 aggtgcgcag cgcagtggcc agcgcggagg gcgagcgact ccgccggctg cgggaacggg
      661 tggaggcgca ggagtccaag ctgcgacgcc tgcgagcgct gcggggtcaa gtggatctgc
      721 agaagaccta caatgtcaca ctgagcaatg acttggactc gattcgtgca ctgttcagcg
      781 agaaggagaa ggagctcagt ttggccgtgg ccaaggtgga ggctttgacc cggcaactgg
      841 aggagctgcg acgtgaccga cgatgtcctg tgaatatcct gacagcagct ggcaacggag
      901 ttggtggtca gtcgcttcca ccgcaggcat cccgcgaact ggagaagctg cgtcgcgaac
      961 tgatgtaccg caatcagttg tcgcttcagc aggatgcacg cttgcacatg caacgtgagg
     1021 cactgcagca aaggcaggcg gagctgcggt ccaccgacca gcgcatttac gagctgcaga
     1081 cgcgcctgca gcgcaaaaag caggccaaca cccatcatca gcagcagcag cagcaacagc
     1141 agcagcacca acaacagcaa catcagcagc agcatcaaca gaccacagtg caacaacagc
     1201 agcagcagca gcagcaactg catgtgcagt ctgcacaatt gctggcggca gcagcagcag
     1261 caactgccca gcagcaacag cagcaccaac aacaccaaca gcagcaacaa cagcagcagc
     1321 agcaaagtgc cagcaatctg ggcaaacatg gtggagtggc cgccctgaag cagcaactgc
     1381 tgcagaagca ggtcaatcaa ctggcagctg ctgctgccgc cgcagccgct ggacgagccc
     1441 gcggcaatgt ggcagccgtt gagcccttca tccacacgcc ccaaaagtcc accatcacga
     1501 gcacggccag ctatctgagc ggtgggatga agcatgcagc ggccacggcc aataccaacc
     1561 agcagaacca gctcattcag gacttgacgc acgtcaagct gggacaaaac agtggcttct
     1621 ttgccggctc cgtgcccgtg cccgtggcca gttccagctg cgaaagcgat gaatccaagt
     1681 tggccaaaaa gctgctggcg gctccggcca aaacggaggc tgagctgcgc aagcaggcgc
     1741 aaacggaggc catggacagt accacacata tctacgcgga ggtgggaccc aagaaacgag
     1801 atcgagaagc agcagcggca gcagcagcag cagcagcagc agcagcagcg gcagctcagg
     1861 cagcagcaga ggcagcaaat caggccgcaa ctgcagcagc agcatccgca atatctccac
     1921 ccgccactgc aaatgccagc aaaatcccca agagcaccac atcgagcagc agttcggcct
     1981 cggcactgat tagcaaactc aaccagcagg cgacggcgaa ggagagccag gatcagcagc
     2041 aatcccaagc caagaagaac gagatttcgg tgaccagcga aacgctttcg gagcgcaaca
     2101 cgcagcagca acttaccgtg cacagcatgc ctctgggggc tattagcaaa tcagtagctc
     2161 ttgccgtttc caatgcctcc aagccgctcc aggtgcaggt gagcaacgtg gccgtgccgc
     2221 cacgcaaacc catcagcagt gtggcgccca attcggtttc cagcggcagc tccataccca
     2281 aaatgatcac ctacagcccc aaggtgaatc gcgtggcgcc caatgtggtg atgacggatc
     2341 cgcgaccagc gctgccgccc aagcctagca agatgtcgcc cacagagcag ccatcaccag
     2401 tggaggccaa tacgtccgga tccgccggcg gagcaggtag tggagcagcg tcggcatcga
     2461 ctgctaataa gacgcaaacg gccacctttg gactgcaatc ccttaacatc aacgacaatt
     2521 tacccatcaa agcgaagcca ctgaccatcc gcaagcagcc gctgttcgag caacctcgcc
     2581 tcaagtccag ccaatccagt tccaatggcc aacagaagcc gcctctgttg cagttgcaaa
     2641 accagcggaa atccgagcct tcagctagac agccaacgga gaacttgccg gacacatcgc
     2701 cccaacattc accgagcagt gaatccagcg cggatgaaac ggatagaatg gtggccccca
     2761 gcatcacgac cagtcaacag gagacatcaa catccgcaac atccaccacg acaaccgtga
     2821 caaccagcaa catcaaggag cgaacgggaa acggaaaacc caagctgggt cgaagggtca
     2881 gctttgatcc gctggccctg ctgctggacg ccagtttgga aggagaactg gaactggtca
     2941 agaagacggc catgcaagtg gccaatccca gtgctgccaa cgatgagggg attacagcgc
     3001 tacacaatgc catctgtgcc ggccacattg acattgtcaa attcctcgtt gagtttggct
     3061 gcgatgtgaa tgcccaggac tcggatggct ggacgccatt gcattgtgcc gccagctgca
     3121 ataatctgtc catggtcaag ttcctggtgg agagcggcgc gtgtctgttt gcctccacgc
     3181 tgtcggatca cgagacgccg gcggagaagt gcgaggagga tgaggaggga ttcgatggct
     3241 gctccgagta tttatacagc attcaggaga agctgggcat cctgcacaat ggcgacgtgt
     3301 acgccgtgtt ctcctacgag gcccaaaacg gagacgagct ctccttccac gtcaacgagc
     3361 cactgatcgt gctgcgcaag ggcgacgatg ccgagaacga gtggtggtgg gcacggaatg
     3421 ccgccggcga ggagggctac gtgccccgca atctcctggg gctgtacccg cgtgtgccgc
     3481 cgcattcgcc gcacttcagc gattagcagt taatacgctt caccatactg aagcgcaagg
     3541 ccggtcgact catccagaag cgctatatat ccaagtacat ctagggaccg tccgacgcag
     3601 ctagccgatt ctgggcacgt gccaccaccg caggagtcaa cggggaatta tttatcacga
     3661 cgccatgttt ctttatgttt actttttgtt tgggaaaagc aacacaaaag gacgagagga
     3721 ggcggatgga gggaggagca aaacgaggct caccatatgc tcatccatat ggaatggaac
     3781 cgactgcagc ttccgcttga gtcatttatc ccgacgactg ccctcaatta gccaggcttt
     3841 cgcacaaagt tcagcacagc aaaacacaca tatcagccgc atatcagcca cataccacca
     3901 catactaccc acgagcatat cgccgcccac caccccctgc atacgtacaa cagcaaattg
     3961 aatttcactt aagctcctta gctttaaggc ctagactaat aactcatatc agccgcccgc
     4021 tcgccacaaa aacttcacct tcaagtcgct gcagaaaaag ttctgattgc aatttgcagc
     4081 caggaaaatg gaaaattgaa aattagaaat ttaaaattta aaatttctca aaggccgcac
     4141 acacacacac actctgtgtg tgtgtgtttc atcaacggat agctgaagga gctgaagttt
     4201 gttaattgca tatatcaagt tagtacttaa actttaattg aactcgaaca aagttcacgc
     4261 taatcgaaag gcaacatttt aacacttata acaaaactcg caaacgcaca cacacacaca
     4321 cacacataca caagcagaat acataacgaa tcgaatgtga tttttgtata aagacgagaa
     4381 taatttaaac aatttgtatc gaatatgaaa atgtaaatta cattaggcgt ggagattcgt
     4441 tgacaagtaa tcgcattata ggctaaatgt tataatttaa cttaatctaa ttacatataa
     4501 tataccgatt gcttaatacc tagcatttaa ggaccaaaca acacacacat tgacatgcaa
     4561 atacgtttga aagatgaaaa taaaacgatt aagaaagctt
//
444..3506
/gene="ASPP"
/locus_tag="Dmel_CG18375"
/gene_synonym="CG18375; dASPP; Dmel\CG18375"
/note="CG18375 gene product from transcript CG18375-RA;
CG18375-PA; ASPP-PA; Ankyrin-repeat, SH3-domain and
Proline-rich-region containing protein"
/codon_start=1
/product="Ankyrin-repeat, SH3-domain, and
Proline-rich-region containing protein, isoform A"
/protein_id="NP_611565.2"
/db_xref="FLYBASE:FBpp0071548"
/db_xref="GeneID:37422"
/db_xref="FLYBASE:FBgn0034606"
/translation="MKEPTNTLDEIVPSRLTSAELRAMALRQQQQIDSQHQLLATKEQ
RLRFLKSQEVRSAVASAEGERLRRLRERVEAQESKLRRLRALRGQVDLQKTYNVTLSN
DLDSIRALFSEKEKELSLAVAKVEALTRQLEELRRDRRCPVNILTAAGNGVGGQSLPP
QASRELEKLRRELMYRNQLSLQQDARLHMQREALQQRQAELRSTDQRIYELQTRLQRK
KQANTHHQQQQQQQQQHQQQQHQQQHQQTTVQQQQQQQQQLHVQSAQLLAAAAAATAQ
QQQQHQQHQQQQQQQQQQSASNLGKHGGVAALKQQLLQKQVNQLAAAAAAAAAGRARG
NVAAVEPFIHTPQKSTITSTASYLSGGMKHAAATANTNQQNQLIQDLTHVKLGQNSGF
FAGSVPVPVASSSCESDESKLAKKLLAAPAKTEAELRKQAQTEAMDSTTHIYAEVGPK
KRDREAAAAAAAAAAAAAAAAQAAAEAANQAATAAAASAISPPATANASKIPKSTTSS
SSSASALISKLNQQATAKESQDQQQSQAKKNEISVTSETLSERNTQQQLTVHSMPLGA
ISKSVALAVSNASKPLQVQVSNVAVPPRKPISSVAPNSVSSGSSIPKMITYSPKVNRV
APNVVMTDPRPALPPKPSKMSPTEQPSPVEANTSGSAGGAGSGAASASTANKTQTATF
GLQSLNINDNLPIKAKPLTIRKQPLFEQPRLKSSQSSSNGQQKPPLLQLQNQRKSEPS
ARQPTENLPDTSPQHSPSSESSADETDRMVAPSITTSQQETSTSATSTTTTVTTSNIK
ERTGNGKPKLGRRVSFDPLALLLDASLEGELELVKKTAMQVANPSAANDEGITALHNA
ICAGHIDIVKFLVEFGCDVNAQDSDGWTPLHCAASCNNLSMVKFLVESGACLFASTLS
DHETPAEKCEEDEEGFDGCSEYLYSIQEKLGILHNGDVYAVFSYEAQNGDELSFHVNE
PLIVLRKGDDAENEWWWARNAAGEEGYVPRNLLGLYPRVPPHSPHFSD"
Feature NM_137721 : 1 segment
Display: FASTA GenBank Help
Details

Supplemental Content

Change region shown

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Reference sequence information

  • RefSeq alternative splicing
    See 3 reference mRNA sequence splice variants for the ASPP gene.
  • RefSeq protein product
    See the reference protein sequence for Ankyrin-repeat, SH3-domain, and Proline-rich-region containing protein, isoform A (NP_611565.2).

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