U.S. flag

An official website of the United States government

RecName: Full=Calbindin-32

UniProtKB/Swiss-Prot: P41044.1

Identical Proteins FASTA Graphics 

LOCUS       CAB32_DROME              310 aa            linear   INV 27-NOV-2024
DEFINITION  RecName: Full=Calbindin-32.
ACCESSION   P41044
VERSION     P41044.1
DBSOURCE    UniProtKB: locus CAB32_DROME, accession P41044;
            class: standard.
            extra accessions:Q9V7W4
            created: Feb 1, 1995.
            sequence updated: Feb 1, 1995.
            annotation updated: Nov 27, 2024.
            xrefs: X68566.1, CAA48566.1, S59242.1, AAA15214.1, S59190.1,
            S59191.1, AE013599.5, AAF57925.1, AY058340.1, AAL13569.1, S37695,
            NP_001286511.1, NP_476838.1
            xrefs (non-sequence databases): AlphaFoldDB:P41044, SMR:P41044,
            BioGRID:62607, STRING:7227.FBpp0086204, PaxDb:7227-FBpp0086204,
            DNASU:36905, EnsemblMetazoa:FBtr0087056,
            EnsemblMetazoa:FBpp0086204, EnsemblMetazoa:FBgn0004580,
            EnsemblMetazoa:FBtr0340072, EnsemblMetazoa:FBpp0309078,
            GeneID:36905, KEGG:dme:Dmel_CG6702, AGR:FB:FBgn0004580, CTD:36905,
            FlyBase:FBgn0004580, VEuPathDB:VectorBase:FBgn0004580,
            eggNOG:KOG0027, GeneTree:ENSGT00950000183108,
            HOGENOM:CLU_054826_1_0_1, InParanoid:P41044, OMA:IVLCNEP,
            OrthoDB:3218718at2759, PhylomeDB:P41044, BioGRID-ORCS:36905,
            GenomeRNAi:36905, PRO:PR:P41044, Proteomes:UP000000803,
            Bgee:FBgn0004580, ExpressionAtlas:P41044, GO:0005829, GO:0030425,
            GO:0005634, GO:0045202, GO:0043195, GO:0061175, GO:0097467,
            GO:0005509, GO:1900271, GO:0099509, CDD:cd16179,
            FunFam:1.10.238.10:FF:000054, FunFam:1.10.238.10:FF:000262,
            FunFam:1.10.238.10:FF:000304, Gene3D:1.10.238.10,
            InterPro:IPR051001, InterPro:IPR011992, InterPro:IPR018247,
            InterPro:IPR002048, InterPro:IPR035799, PANTHER:PTHR19972,
            PANTHER:PTHR19972:SF10, Pfam:PF00036, Pfam:PF13499, SMART:SM00054,
            SUPFAM:SSF47473, PROSITE:PS00018, PROSITE:PS50222
KEYWORDS    Calcium; Metal-binding; Reference proteome; Repeat.
SOURCE      Drosophila melanogaster (fruit fly)
  ORGANISM  Drosophila melanogaster
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
REFERENCE   1  (residues 1 to 310)
  AUTHORS   Reifegerste,R., Grimm,S., Albert,S., Lipski,N., Heimbeck,G.,
            Hofbauer,A., Pflugfelder,G.O., Quack,D., Reichmuth,C., Schug,B.,
            Zinsmaier,K.E., Buchner,S. and Buchner,E.
  TITLE     An invertebrate calcium-binding protein of the calbindin subfamily:
            protein structure, genomic organization, and expression pattern of
            the calbindin-32 gene of Drosophila
  JOURNAL   J Neurosci 13 (5), 2186-2198 (1993)
   PUBMED   8478695
  REMARK    NUCLEOTIDE SEQUENCE [MRNA].;
            STRAIN=Berlin; TISSUE=Brain
REFERENCE   2  (residues 1 to 310)
  AUTHORS   Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D.,
            Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F.,
            George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N.,
            Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X.,
            Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D.,
            Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L.,
            Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D.,
            Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M.,
            Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S.,
            Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P.,
            Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A.,
            Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B.,
            Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I.,
            Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S.,
            Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C.,
            Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S.,
            Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z.,
            Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J.,
            Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J.,
            Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z.,
            Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C.,
            Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A.,
            Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C.,
            McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C.,
            Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L.,
            Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K.,
            Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S.,
            Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K.,
            Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I.,
            Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C.,
            Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R.,
            Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A.,
            Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT,
            Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F.,
            Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H.,
            Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O.,
            Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C.
  TITLE     The genome sequence of Drosophila melanogaster
  JOURNAL   Science 287 (5461), 2185-2195 (2000)
   PUBMED   10731132
  REMARK    NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].;
            STRAIN=Berkeley
REFERENCE   3  (residues 1 to 310)
  AUTHORS   Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S.,
            Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E.,
            Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L.,
            Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D.,
            Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J.,
            Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M.,
            Rubin,G.M. and Lewis,S.E.
  TITLE     Annotation of the Drosophila melanogaster euchromatic genome: a
            systematic review
  JOURNAL   Genome Biol 3 (12), RESEARCH0083 (2002)
   PUBMED   12537572
  REMARK    GENOME REANNOTATION.;
            STRAIN=Berkeley
REFERENCE   4  (residues 1 to 310)
  AUTHORS   Stapleton,M., Carlson,J., Brokstein,P., Yu,C., Champe,M.,
            George,R., Guarin,H., Kronmiller,B., Pacleb,J., Park,S., Wan,K.,
            Rubin,G.M. and Celniker,S.E.
  TITLE     A Drosophila full-length cDNA resource
  JOURNAL   Genome Biol 3 (12), RESEARCH0080 (2002)
   PUBMED   12537569
  REMARK    NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].;
            STRAIN=Berkeley; TISSUE=Head
COMMENT     On Mar 15, 2005 this sequence version replaced gi:481058.
            [TISSUE SPECIFICITY] Expressed in a large number of neuron of the
            brain and the thoracic ganglion as well as in two small muscles of
            the thorax.
            [SIMILARITY] Belongs to the calbindin family. {ECO:0000305}.
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Drosophila melanogaster"
                     /db_xref="taxon:7227"
     gene            1..310
                     /gene="Cbp53E"
                     /locus_tag="CG6702"
                     /gene_synonym="cbn"
     Protein         1..310
                     /product="Calbindin-32"
                     /UniProtKB_evidence="Evidence at transcript level"
     Region          1..310
                     /region_name="Mature chain"
                     /note="Calbindin-32. /id=PRO_0000073477."
     Region          35..70
                     /region_name="Domain"
                     /note="EF-hand 1.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU00448."
     Region          40..301
                     /region_name="EFh_HEF_CBN"
                     /note="EF-hand, calcium binding motif, found in Drosophila
                     melanogaster calbindin-32 (CBN) and similar proteins;
                     cd16179"
                     /db_xref="CDD:320079"
     Region          40..68
                     /region_name="EF-hand motif"
                     /note="EF-hand motif [structural motif]"
                     /db_xref="CDD:320079"
     Site            order(48,50,52,59,98,100,102,109,144,146,148,155,190,192,
                     194,201,237,239,241,248)
                     /site_type="other"
                     /note="putative Ca binding site [ion binding]"
                     /db_xref="CDD:320079"
     Region          84..120
                     /region_name="Domain"
                     /note="EF-hand 2.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU00448."
     Region          89..118
                     /region_name="EF-hand motif"
                     /note="EF-hand motif [structural motif]"
                     /db_xref="CDD:320079"
     Region          131..166
                     /region_name="Domain"
                     /note="EF-hand 3.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU00448."
     Region          135..164
                     /region_name="EF-hand motif"
                     /note="EF-hand motif [structural motif]"
                     /db_xref="CDD:320079"
     Region          177..212
                     /region_name="Domain"
                     /note="EF-hand 4.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU00448."
     Region          181..210
                     /region_name="EF-hand motif"
                     /note="EF-hand motif [structural motif]"
                     /db_xref="CDD:320079"
     Region          224..259
                     /region_name="Domain"
                     /note="EF-hand 5.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU00448."
     Region          228..257
                     /region_name="EF-hand motif"
                     /note="EF-hand motif [structural motif]"
                     /db_xref="CDD:320079"
     Region          273..301
                     /region_name="EF-hand motif"
                     /note="EF-hand motif [structural motif]"
                     /db_xref="CDD:320079"
     Region          283..304
                     /region_name="Domain"
                     /note="EF-hand 6.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU00448."
ORIGIN      
        1 mdsaaaaaak rvqiekahnf mrqyrdpesr elkklsanqf mdvwahydkd gngyiegtel
       61 dgflrefvss anatdispea vtdtmleelk scfmeayddn qdgkidirel aqllpmeenf
      121 lllfrfdnpl essvefmkiw reydtdnsgy ieadelknfl rdllkeakki ndvsedklie
      181 ytdtmlqvfd ankdgrlqls emakllpvke nflcrqvfkg atkltkedie kvfslydrdn
      241 sgtieneelk gflkdllelv kkddydaqdl aafeetimrg vgtdkhgkis rkeltmillt
      301 lakispddee
//
Feature
Display: FASTA GenBank Help
Details

Supplemental Content

Change region shown

Customize view

Reference sequence information

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
External link. Please review our privacy policy.