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Items: 1 to 20 of 1095

1.
Retention of ES cell-derived 129S genome drives NLRP1 hypersensitivity and transcriptional deregulation in Nlrp3tm1Flv mice
Felix D. Weiss, Yubell Alvarez, Farhad Shakeri, Anshupa Sahu, Petro Leka, Alesja Dernst, Jessika Rollheiser, Matilde Vasconcelos, Adriana Geraci, Fraser Duthie, Rainer Stahl, Hye Eun Lee, Anne-Kathrin Gellner, Andreas Buness, Eicke Latz, Felix Meissner
Cell Death Differ. 2024 Dec; 31(12): 1717–1729. Published online 2024 Sep 17. doi: 10.1038/s41418-024-01379-2
PMCID:
PMC11618613
AbstractArticlePDF–3.6M
2.
Glyburide Suppresses Inflammation-Related Colorectal Tumorigenesis Through Inhibition of NLRP3 Inflammasome
Toshihide Maeda, Yohei Shirakami, Daisuke Taguchi, Takao Miwa, Masaya Kubota, Hiroyasu Sakai, Takashi Ibuka, Kosuke Mori, Hiroyuki Tomita, Masahito Shimizu
Int J Mol Sci. 2024 Nov; 25(21): 11640. Published online 2024 Oct 30. doi: 10.3390/ijms252111640
PMCID:
PMC11546087
AbstractArticlePDF–2.9M
3.
Glutamine metabolism modulates microglial NLRP3 inflammasome activity through mitophagy in Alzheimer’s disease
Zhixin Zhang, Miao Li, Xiang Li, Zhiyang Feng, Gan Luo, Ying Wang, Xiaoyan Gao
J Neuroinflammation. 2024; 21: 261. Published online 2024 Oct 15. doi: 10.1186/s12974-024-03254-w
PMCID:
PMC11481753
AbstractArticlePDF–3.0M
4.
FTO mediates the diabetic kidney disease progression through regulating the m6A modification of NLRP3
Qiang Li, Shujuan Mu
BMC Nephrol. 2024; 25: 345. Published online 2024 Oct 11. doi: 10.1186/s12882-024-03741-5
PMCID:
PMC11468296
AbstractArticlePDF–9.7M
5.
STAT3 promotes NLRP3 inflammasome activation by mediating NLRP3 mitochondrial translocation
Ling Luo, Fupeng Wang, Xueming Xu, Mingliang Ma, Guangyan Kuang, Yening Zhang, Dan Wang, Wei Li, Ningjie Zhang, Kai Zhao
Exp Mol Med. 2024 Sep; 56(9): 1980–1990. Published online 2024 Sep 2. doi: 10.1038/s12276-024-01298-9
Correction in:
Exp Mol Med. 2024 Sep; 56(9): 2097.
PMCID:
PMC11446920
AbstractArticlePDF–4.5M
6.
Tmem178 negatively regulates IL-1β production through inhibition of the NLRP3 inflammasome
Kunjan Khanna, Hui Yan, Muneshwar Mehra, Nidhi Rohatgi, Gabriel Mbalaviele, Elizabeth D. Mellins, Roberta Faccio
Arthritis Rheumatol. Author manuscript; available in PMC 2025 Jan 1.
Published in final edited form as: Arthritis Rheumatol. 2024 Jan; 76(1): 107–118. Published online 2023 Nov 13. doi: 10.1002/art.42666
PMCID:
PMC11421209
AbstractArticlePDF–2.3M
7.
Osteopontin deficiency promotes cartilaginous endplate degeneration by enhancing the NF-κB signaling to recruit macrophages and activate the NLRP3 inflammasome
Yanqiu Wang, Wanqian Zhang, Yi Yang, Jinghao Qin, Ruoyu Wang, Shuai Wang, Wenjuan Fu, Qin Niu, Yanxia Wang, Changqing Li, Hongli Li, Yue Zhou, Minghan Liu
Bone Res. 2024; 12: 53. Published online 2024 Sep 6. doi: 10.1038/s41413-024-00355-3
PMCID:
PMC11379908
AbstractArticlePDF–9.5M
8.
RVFV virulence factor NSs triggers the mitochondrial MCL-1-BAK axis to activate pathogenic NLRP3 pyroptosis
Zhenqiong Guan, Huiling Li, Chongtao Zhang, Ziyan Huang, Meidi Ye, Yulan Zhang, Shufen Li, Ke Peng
PLoS Pathog. 2024 Aug; 20(8): e1012387. Published online 2024 Aug 30. doi: 10.1371/journal.ppat.1012387
PMCID:
PMC11364418
AbstractArticlePDF–3.7M
9.
Diabetic Wound Keratinocytes Induce Macrophage JMJD3-Mediated Nlrp3 Expression via IL-1R Signaling
Sonya J. Wolf, Christopher O. Audu, Jadie Y. Moon, Amrita D. Joshi, William J. Melvin, Emily C. Barrett, Kevin Mangum, Gabriela Saldana de Jimenez, Sabrina Rocco, Sam Buckley, Zara Ahmed, Rachael Wasikowski, J. Michelle Kahlenberg, Lam C. Tsoi, Johann E. Gudjonsson, Katherine A. Gallagher
Diabetes. 2024 Sep; 73(9): 1462–1472. Published online 2024 Jun 13. doi: 10.2337/db23-0968
PMCID:
PMC11333374
AbstractArticlePDF–52M
10.
NLRP3-mediated autophagy dysfunction links gut microbiota dysbiosis to tau pathology in chronic sleep deprivation
Na Zhao, Xiu Chen, Qiu-Gu Chen, Xue-Ting Liu, Fan Geng, Meng-Meng Zhu, Fu-Ling Yan, Zhi-Jun Zhang, Qing-Guo Ren
Zool Res. 2024 Jul 18; 45(4): 857–874. doi: 10.24272/j.issn.2095-8137.2024.085
PMCID:
PMC11298670
AbstractArticlePDF–12M
11.
Glycolytic enzyme PGK1 promotes M1 macrophage polarization and induces pyroptosis of acute lung injury via regulation of NLRP3
Guiyin Zhu, Haiyang Yu, Tian Peng, Kun Yang, Xue Xu, Wen Gu
Respir Res. 2024; 25: 291. Published online 2024 Jul 30. doi: 10.1186/s12931-024-02926-8
PMCID:
PMC11290129
AbstractArticlePDF–11M
12.
Elevated NLRP3 Inflammasome Activation Is Associated with Motor Neuron Degeneration in ALS
Hilal Cihankaya, Verian Bader, Konstanze F. Winklhofer, Matthias Vorgerd, Johann Matschke, Sarah Stahlke, Carsten Theiss, Veronika Matschke
Cells. 2024 Jun; 13(12): 995. Published online 2024 Jun 7. doi: 10.3390/cells13120995
PMCID:
PMC11202041
AbstractArticlePDF–2.8M
13.
NLRP3 promotes allergic responses to birch pollen extract in a model of intranasal sensitization
Renate Bauer, Hieu-Hoa Dang, Daniel Neureiter, Michael Stefan Unger, Theresa Neuper, Melanie Jensen, Alice Emma Taliento, Helen Strandt, Iris Gratz, Richard Weiss, Angelika Sales, Jutta Horejs-Hoeck
Front Immunol. 2024; 15: 1393819. Published online 2024 Jun 12. doi: 10.3389/fimmu.2024.1393819
PMCID:
PMC11199694
AbstractArticlePDF–9.8M
14.
Neutrophil NLRP3 promotes cardiac injury following acute myocardial infarction through IL-1β production, VWF release and NET deposition in the myocardium
Lukas A. Heger, Nicolas Schommer, Stijn Van Bruggen, Casey E. Sheehy, William Chan, Denisa D. Wagner
Sci Rep. 2024; 14: 14524. Published online 2024 Jun 24. doi: 10.1038/s41598-024-64710-4
PMCID:
PMC11196583
AbstractArticlePDF–3.0M
15.
Pulmonary inflammation and viral replication define distinct clinical outcomes in fatal cases of COVID-19
Keyla S. G. de Sá, Luana A. Amaral, Tamara S. Rodrigues, Camila C. S. Caetano, Amanda Becerra, Sabrina S. Batah, Felipe T. Lopes, Isadora M. de Oliveira, Letícia S. Lopes, Leticia Almeida, Caroline M. Mota, Samuel Oliveira, Danilo T. Wada, Marcel Koenigkam-Santos, Ronaldo B. Martins, Roberta R. C. Rosales, Eurico Arruda, Alexandre T. Fabro, Dario S. Zamboni
PLoS Pathog. 2024 Jun; 20(6): e1012222. Published online 2024 Jun 5. doi: 10.1371/journal.ppat.1012222
PMCID:
PMC11182505
AbstractArticlePDF–3.9M
16.
Monocyte‐Derived Macrophages Aggravate Cardiac Dysfunction After Ischemic Stroke in Mice
Hong‐Bin Lin, Pu Hong, Meng‐Yu Yin, Zhi‐Jun Yao, Jin‐Yu Zhang, Yan‐Pin Jiang, Xuan‐Xuan Huang, Shi‐Yuan Xu, Feng‐Xian Li, Hong‐Fei Zhang
J Am Heart Assoc. 2024 May 7; 13(9): e034731. Published online 2024 May 3. doi: 10.1161/JAHA.123.034731
PMCID:
PMC11179859
AbstractArticlePDF–23M
17.
NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation
Tao Yu, Dan Hou, Jiaqi Zhao, Xuan Lu, Wendy K. Greentree, Qian Zhao, Min Yang, Don-Gerard Conde, Maurine E. Linder, Hening Lin
Cell Rep. Author manuscript; available in PMC 2024 May 28.
Published in final edited form as: Cell Rep. 2024 Apr 23; 43(4): 114070. Published online 2024 Apr 6. doi: 10.1016/j.celrep.2024.114070
PMCID:
PMC11130711
AbstractArticlePDF–3.0M
18.
miRNA-206-3p alleviates LPS-induced acute lung injury via inhibiting inflammation and pyroptosis through modulating TLR4/NF-κB/NLRP3 pathway
Mengchi Chen, Jingfeng Zhang, Hongyuan Huang, Zichen Wang, Yong Gao, Jianghua Liu
Sci Rep. 2024; 14: 11860. Published online 2024 May 24. doi: 10.1038/s41598-024-62733-5
PMCID:
PMC11126654
AbstractArticlePDF–9.1M
19.
YOD1 protects against MRSA sepsis-induced DIC through Lys33-linked deubiquitination of NLRP3
Chang Liu, Caihong Fan, Jia Liu, Shiqi Zhang, Huixin Tang, Yashan Liu, Shengzheng Zhang, Qiang Wu, Jiandong Zhang, Zhi Qi, Yanna Shen
Cell Death Dis. 2024 May; 15(5): 360. Published online 2024 May 24. doi: 10.1038/s41419-024-06731-5
Correction in:
Cell Death Dis. 2024 Sep; 15(9): 651.
PMCID:
PMC11126606
AbstractArticlePDF–4.3M
20.
Intestinal microflora promotes Th2-mediated immunity through NLRP3 in damp and heat environments
Yi Luo, Xinhua Huang, Haiying Hu, Yao Wang, Xiangrong Feng, Song Chen, Huanhuan Luo
Front Immunol. 2024; 15: 1367053. Published online 2024 May 2. doi: 10.3389/fimmu.2024.1367053
PMCID:
PMC11096527
AbstractArticlePDF–10M

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