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    Rilp Rab interacting lysosomal protein [ Mus musculus (house mouse) ]

    Gene ID: 280408, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rilpprovided by MGI
    Official Full Name
    Rab interacting lysosomal proteinprovided by MGI
    Primary source
    MGI:MGI:2144271
    See related
    Ensembl:ENSMUSG00000038195 AllianceGenome:MGI:2144271
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm857
    Summary
    Predicted to enable dynein light intermediate chain binding activity and small GTPase binding activity. Predicted to be involved in several processes, including endosomal transport; intralumenal vesicle formation; and regulation of protein catabolic process. Located in mitochondrion. Part of protein-containing complex. Is expressed in brown fat; ileum; liver; male reproductive gland or organ; and metanephros. Orthologous to human RILP (Rab interacting lysosomal protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in heart adult (RPKM 16.4), liver adult (RPKM 13.1) and 19 other tissues See more
    Orthologs
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    Genomic context

    See Rilp in Genome Data Viewer
    Location:
    11 B5; 11 45.92 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (75400920..75403994)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (75510094..75513168)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene TLC domain containing 2 Neighboring gene STARR-positive B cell enhancer ABC_E591 Neighboring gene pre-mRNA processing factor 8 Neighboring gene STARR-positive B cell enhancer ABC_E7017 Neighboring gene scavenger receptor class F, member 1 Neighboring gene STARR-positive B cell enhancer ABC_E9036 Neighboring gene STARR-positive B cell enhancer ABC_E10689 Neighboring gene STARR-seq mESC enhancer starr_29997 Neighboring gene solute carrier family 43, member 2 Neighboring gene predicted gene 45606

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables dynein light intermediate chain binding  
    enables dynein light intermediate chain binding  
    enables dynein light intermediate chain binding  
    enables protein binding PubMed 
    enables protein dimerization activity  
    enables small GTPase binding  
    enables small GTPase binding  
    enables small GTPase binding  
    Process Evidence Code Pubs
    involved_in cilium assembly  
    involved_in early endosome to late endosome transport  
    involved_in early endosome to late endosome transport  
    involved_in early endosome to late endosome transport  
    involved_in endosome to lysosome transport  
    involved_in endosome to lysosome transport  
    involved_in endosome transport via multivesicular body sorting pathway  
    involved_in endosome transport via multivesicular body sorting pathway  
    involved_in intralumenal vesicle formation  
    involved_in intralumenal vesicle formation  
    involved_in negative regulation of protein catabolic process  
    involved_in negative regulation of protein catabolic process  
    involved_in positive regulation of protein catabolic process  
    involved_in positive regulation of protein catabolic process  
    involved_in protein transport  
    Component Evidence Code Pubs
    is_active_in ciliary basal body  
    is_active_in cytoplasm  
    located_in late endosome  
    located_in late endosome membrane  
    located_in lysosomal membrane  
    is_active_in lysosome  
    located_in lysosome  
    located_in mitochondrion PubMed 
    located_in phagocytic vesicle membrane  
    part_of protein-containing complex PubMed 

    General protein information

    Preferred Names
    rab-interacting lysosomal protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001029938.2NP_001025109.1  rab-interacting lysosomal protein

      See identical proteins and their annotated locations for NP_001025109.1

      Status: VALIDATED

      Source sequence(s)
      AK139016, AK160517, AW012811, BC038146
      Consensus CDS
      CCDS25049.1
      UniProtKB/Swiss-Prot
      Q5ND29, Q80WB8, Q8CHY9
      UniProtKB/TrEMBL
      Q14AQ2
      Related
      ENSMUSP00000037238.7, ENSMUST00000042972.7
      Conserved Domains (2) summary
      cd14445
      Location:11107
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
      pfam11461
      Location:224281
      RILP; Rab interacting lysosomal protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      75400920..75403994
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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