Parous mammary gland response to N-methyl-N-nitrosourea
Summary:
Analysis of mammary gland from parous or virgin Lewis animals 3 weeks after treatment with 50 mg/kg of N-methyl-N-nitrosourea, a carcinogen. Full-term pregnancy early in life is associated with a reduced chance of developing breast cancer.
GPL890:
Agilent-011868 Rat Oligo Microarray G4130A (Feature Number version)
Citation:
Uehara N, Unami A, Kiyozuka Y, Shikata N et al. Parous mammary glands exhibit distinct alterations in gene expression and proliferation responsiveness to carcinogenic stimuli in Lewis rats. Oncol Rep 2006 Apr;15(4):903-11. PMID: 16525678
