Analysis of liver from obesity-prone (OP) Wistar males with nonalcoholic fatty liver disease (NAFLD) induced by a 16 week, high-fat diet (HFD). Obesity-resistant (OR) males, fed an identical diet, were also examined. Results provide insight into molecular mechanisms underlying NAFLD pathogenesis.
Xie Z, Li H, Wang K, Lin J et al. Analysis of transcriptome and metabolome profiles alterations in fatty liver induced by high-fat diet in rat. Metabolism 2010 Apr;59(4):554-60. PMID: 19913842