Akt transgenic response to lymphocytic choriomeningitis virus (LCMV) infection: CD8 T cell types
Summary:
Analysis of naïve CD8 T cells, short-lived effector or memory precursor effector cells from LCMV-infected P14/WT or P14/Akt transgenic females. Results provide insight into the role of Akt in effector and memory CD8 T cell differentiation during viral infection.
Kim EH, Sullivan JA, Plisch EH, Tejera MM et al. Signal integration by Akt regulates CD8 T cell effector and memory differentiation. J Immunol 2012 May 1;188(9):4305-14. PMID: 22467649
