Kruppel-like factor 5 deficiency in bladder epithelial cells effect on the fetal bladder
Summary:
Analysis of fetal bladders with Kruppel-like transcription factor 5 (KLF5) deficiency specific to bladder epithelial cells. KLF5 is expressed in proliferative epithelial cell types during embryogenesis. Results provide insight into the role of KLF5 in the development of the bladder urothelium.
Bell SM, Zhang L, Mendell A, Xu Y et al. Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium. Dev Biol 2011 Oct 1;358(1):79-90. PMID: 21803035