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    SLC12A2 solute carrier family 12 member 2 [ Macaca fascicularis (crab-eating macaque) ]

    Gene ID: 101865866, updated on 19-Jun-2024

    Summary

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    Gene symbol
    SLC12A2
    Gene description
    solute carrier family 12 member 2
    See related
    Ensembl:ENSMFAG00000001384
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca fascicularis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SLC12A2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 6 NC_088380.1 (134671682..134775011)
    102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 6 NC_052260.1 (123318241..123421410)

    Chromosome 6 - NC_088380.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 192 Neighboring gene cullin-1-like Neighboring gene uncharacterized LOC107130062 Neighboring gene uncharacterized LOC135971417 Neighboring gene protein O-glucosyltransferase 2-like Neighboring gene fibrillin 2 Neighboring gene solute carrier family 27 member 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs. Osada N, et al. Mol Biol Evol, 2005 Oct. PMID 15944441
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ammonium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sodium:potassium:chloride symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ammonium transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell volume homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chloride ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chloride transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in potassium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in potassium ion import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    solute carrier family 12 member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference T2T-MFA8v1.0

    Genomic

    1. NC_088380.1 Reference T2T-MFA8v1.0

      Range
      134671682..134775011
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005557674.4 → XP_005557731.1  solute carrier family 12 member 2 isoform X1

      See identical proteins and their annotated locations for XP_005557731.1

      UniProtKB/TrEMBL
      A0A2K5TTA2
      Related
      ENSMFAP00000008154.1
      Conserved Domains (3) summary
      TIGR00930
      Location:214 → 1210
      2a30; K-Cl cotransporter
      pfam03522
      Location:799 → 1210
      SLC12; Solute carrier family 12
      pfam08403
      Location:200 → 261
      AA_permease_N; Amino acid permease N-terminal

    2. XM_005557675.4 → XP_005557732.1  solute carrier family 12 member 2 isoform X2

      See identical proteins and their annotated locations for XP_005557732.1

      UniProtKB/TrEMBL
      A0A2K5TTA8
      Related
      ENSMFAP00000008162.1
      Conserved Domains (3) summary
      TIGR00930
      Location:214 → 1194
      2a30; K-Cl cotransporter
      pfam03522
      Location:799 → 1194
      SLC12; Solute carrier family 12
      pfam08403
      Location:200 → 261
      AA_permease_N; Amino acid permease N-terminal
    Nucleotide Protein
    Heading Accession and Version

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