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    Zfp982 zinc finger protein 982 [ Mus musculus (house mouse) ]

    Gene ID: 195531, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp982provided by MGI
    Official Full Name
    zinc finger protein 982provided by MGI
    Primary source
    MGI:MGI:3701121
    See related
    Ensembl:ENSMUSG00000078496 AllianceGenome:MGI:3701121
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm13152
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nuclear body and nucleolus. Predicted to be active in nucleus. Is expressed in epiblast and primitive endoderm. Orthologous to several human genes including ZNF300 (zinc finger protein 300); ZNF486 (zinc finger protein 486); and ZNF506 (zinc finger protein 506). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in bladder adult (RPKM 1.7), CNS E11.5 (RPKM 1.3) and 17 other tissues See more
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    Genomic context

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    See Zfp982 in Genome Data Viewer
    Location:
    4 E1; 4 78.5 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (147527571..147600521)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (147443114..147516064)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr4:146680009-146680309 Neighboring gene STARR-seq mESC enhancer starr_12051 Neighboring gene zinc finger protein 988 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146701337-146701637 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146707438-146707739 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146708882-146709183 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146709639-146709939 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146710317-146710618 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146711266-146711567 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146711748-146712049 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146713593-146713894 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146718347-146718647 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146719638-146719939 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146732156-146732457 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146734141-146734442 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146736508-146736808 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146739365-146739666 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146751603-146751903 Neighboring gene zinc finger protein 978 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146754866-146755167 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146762351-146762652 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146764074-146764374 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146766178-146766479 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146766804-146767105 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146768262-146768563 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146769615-146769916 Neighboring gene high mobility group box 1-like pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E3547 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146779152-146779453 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146779533-146779834 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146779911-146780211 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146782049-146782350 Neighboring gene STARR-seq mESC enhancer starr_12053 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146793859-146794160 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146795582-146795882 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146801970-146802271 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146802879-146803179 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146803319-146803620 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146804225-146804526 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146805098-146805399 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146808010-146808311 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146808409-146808709 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146811551-146811852 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146812536-146812836 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146813710-146814011 Neighboring gene STARR-seq mESC enhancer starr_12054 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146820564-146820864 Neighboring gene STARR-seq mESC enhancer starr_12055 Neighboring gene vomeronasal 2, receptor, pseudogene 19 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146826142-146826443 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146830236-146830536 Neighboring gene tousled-like kinase 2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_12056 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146871800-146872101 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146881635-146881936 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146883327-146883628 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146885233-146885534 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146893742-146894043 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146896025-146896326 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146898623-146898924 Neighboring gene STARR-positive B cell enhancer ABC_E10290 Neighboring gene vomeronasal 2, receptor, pseudogene 20 Neighboring gene 60S ribosomal protein L29 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. ZFP982 confers mouse embryonic stem cell characteristics by regulating expression of Nanog, Zfp42, and Dppa3. Dehghanian F, et al. Biochim Biophys Acta Mol Cell Res, 2024 Apr. PMID 38342310
    2. Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages. Dietrich JE, et al. EMBO Rep, 2015 Aug. PMID 26142281, Free PMC Article
    3. Transcriptome analysis of mouse stem cells and early embryos. Sharov AA, et al. PLoS Biol, 2003 Dec. PMID 14691545, Free PMC Article
    4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    5. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ZFP982 confers mouse embryonic stem cell characteristics by regulating expression of Nanog, Zfp42, and Dppa3.
      Title: ZFP982 confers mouse embryonic stem cell characteristics by regulating expression of Nanog, Zfp42, and Dppa3.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Clone Names

    • MGC60813, MGC76795

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC195531

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039209.4 → NP_001034298.2  uncharacterized protein LOC195531

      Status: VALIDATED

      Source sequence(s)
      AL626778
      Consensus CDS
      CCDS84824.1
      UniProtKB/TrEMBL
      A2A8Q4
      Related
      ENSMUSP00000068021.8, ENSMUST00000063704.8
      Conserved Domains (3) summary
      COG5048
      Location:71 → 349
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:216 → 236
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    2. NM_001365422.2 → NP_001352351.1  uncharacterized protein LOC195531

      Status: VALIDATED

      Source sequence(s)
      AL626778
      Consensus CDS
      CCDS84824.1
      UniProtKB/TrEMBL
      A2A8Q4
      Related
      ENSMUSP00000101346.3, ENSMUST00000105721.9
      Conserved Domains (3) summary
      COG5048
      Location:71 → 349
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:216 → 236
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    3. NM_001371348.1 → NP_001358277.1  uncharacterized protein LOC195531

      Status: VALIDATED

      Source sequence(s)
      AL626778
      Consensus CDS
      CCDS84824.1
      UniProtKB/TrEMBL
      A2A8Q4
      Conserved Domains (3) summary
      COG5048
      Location:71 → 349
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:216 → 236
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    4. NM_001371349.1 → NP_001358278.1  uncharacterized protein LOC195531

      Status: VALIDATED

      Source sequence(s)
      AL626778
      Consensus CDS
      CCDS84824.1
      UniProtKB/TrEMBL
      A2A8Q4
      Conserved Domains (3) summary
      COG5048
      Location:71 → 349
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:216 → 236
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      147527571..147600521
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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