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    GRAMD4 GRAM domain containing 4 [ Gallus gallus (chicken) ]

    Gene ID: 425953, updated on 3-Dec-2024

    Summary

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    Symbol
    GRAMD4provided by CGNC
    Full Name
    GRAM domain containing 4provided by CGNC
    Primary source
    CGNC:52622
    See related
    Ensembl:ENSGALG00010008745
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See GRAMD4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (16121734..16198685)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (16258893..16335872)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase Neighboring gene cadherin EGF LAG seven-pass G-type receptor 1 Neighboring gene histone cluster 1, H2B-V-like (similar to human histone cluster 1, class H2B genes) Neighboring gene uncharacterized LOC121108891 Neighboring gene uncharacterized LOC121108893 Neighboring gene uncharacterized LOC121109179

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of toll-like receptor 9 signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GRAM domain-containing protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      16121734..16198685
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040657095.2 → XP_040513029.1  GRAM domain-containing protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XZ39
      Conserved Domains (4) summary
      COG4372
      Location:100 → 249
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      PRK09510
      Location:120 → 182
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      cd13221
      Location:503 → 608
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam08372
      Location:329 → 409
      PRT_C; Plant phosphoribosyltransferase C-terminal

    2. XM_040657125.2 → XP_040513059.1  GRAM domain-containing protein 4 isoform X8

      UniProtKB/TrEMBL
      A0A8V0XZ39
      Related
      ENSGALP00010011992.1, ENSGALT00010020822.1
      Conserved Domains (4) summary
      COG4372
      Location:100 → 249
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      PRK09510
      Location:120 → 182
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      cd13221
      Location:485 → 590
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam08372
      Location:329 → 409
      PRT_C; Plant phosphoribosyltransferase C-terminal

    3. XM_040657079.2 → XP_040513013.1  GRAM domain-containing protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XZ39, A0A8V0Y3E6
      Related
      ENSGALP00010011981.1, ENSGALT00010020788.1
      Conserved Domains (4) summary
      COG4372
      Location:102 → 251
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      PRK09510
      Location:122 → 184
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      cd13221
      Location:505 → 610
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam08372
      Location:331 → 411
      PRT_C; Plant phosphoribosyltransferase C-terminal

    4. XM_040657105.2 → XP_040513039.1  GRAM domain-containing protein 4 isoform X4

      UniProtKB/TrEMBL
      A0A8V0XZ39
      Conserved Domains (3) summary
      COG4372
      Location:102 → 251
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      PRK09510
      Location:122 → 184
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      cd13221
      Location:499 → 604
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain

    5. XM_015275805.4 → XP_015131291.1  GRAM domain-containing protein 4 isoform X6

      UniProtKB/TrEMBL
      A0A8V0XZ39
      Related
      ENSGALP00010011986.1, ENSGALT00010020805.1
      Conserved Domains (3) summary
      COG4372
      Location:102 → 251
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      PRK09510
      Location:122 → 184
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      cd13221
      Location:487 → 592
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain

    6. XM_046943856.1 → XP_046799812.1  GRAM domain-containing protein 4 isoform X9

      UniProtKB/TrEMBL
      A0A8V0XZ39

    7. XM_040657135.2 → XP_040513069.1  GRAM domain-containing protein 4 isoform X9

      UniProtKB/TrEMBL
      A0A8V0XZ39
      Conserved Domains (4) summary
      COG4372
      Location:76 → 225
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      PRK09510
      Location:96 → 158
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      cd13221
      Location:479 → 584
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam08372
      Location:305 → 385
      PRT_C; Plant phosphoribosyltransferase C-terminal

    8. XM_046943861.1 → XP_046799817.1  GRAM domain-containing protein 4 isoform X9

      UniProtKB/TrEMBL
      A0A8V0XZ39

    9. XM_046943847.1 → XP_046799803.1  GRAM domain-containing protein 4 isoform X5

      UniProtKB/TrEMBL
      A0A8V0XZ39

    10. XM_046943862.1 → XP_046799818.1  GRAM domain-containing protein 4 isoform X10

      UniProtKB/TrEMBL
      A0A8V0XZ39

    11. XM_040657086.2 → XP_040513020.1  GRAM domain-containing protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XZ39
      Related
      ENSGALP00010011964.1, ENSGALT00010020742.1
      Conserved Domains (4) summary
      COG4372
      Location:101 → 250
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      PRK09510
      Location:121 → 183
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      cd13221
      Location:504 → 609
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam08372
      Location:330 → 410
      PRT_C; Plant phosphoribosyltransferase C-terminal

    12. XM_046943851.1 → XP_046799807.1  GRAM domain-containing protein 4 isoform X7

      UniProtKB/TrEMBL
      A0A8V0XZ39, A0A8V0Y0X9
      Related
      ENSGALP00010011965.1, ENSGALT00010020747.1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      16258893..16335872
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040659132.2 → XP_040515066.1  GRAM domain-containing protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XZ39
      Conserved Domains (4) summary
      COG4372
      Location:100 → 249
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      PRK09510
      Location:120 → 182
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      cd13221
      Location:503 → 608
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam08372
      Location:329 → 409
      PRT_C; Plant phosphoribosyltransferase C-terminal

    2. XM_040659135.2 → XP_040515069.1  GRAM domain-containing protein 4 isoform X8

      UniProtKB/TrEMBL
      A0A8V0XZ39
      Conserved Domains (4) summary
      COG4372
      Location:100 → 249
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      PRK09510
      Location:120 → 182
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      cd13221
      Location:485 → 590
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam08372
      Location:329 → 409
      PRT_C; Plant phosphoribosyltransferase C-terminal

    3. XM_040659130.2 → XP_040515064.1  GRAM domain-containing protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XZ39, A0A8V0Y3E6
      Conserved Domains (4) summary
      COG4372
      Location:102 → 251
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      PRK09510
      Location:122 → 184
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      cd13221
      Location:505 → 610
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam08372
      Location:331 → 411
      PRT_C; Plant phosphoribosyltransferase C-terminal

    4. XM_040659133.2 → XP_040515067.1  GRAM domain-containing protein 4 isoform X4

      UniProtKB/TrEMBL
      A0A8V0XZ39
      Conserved Domains (3) summary
      COG4372
      Location:102 → 251
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      PRK09510
      Location:122 → 184
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      cd13221
      Location:499 → 604
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain

    5. XM_040659134.2 → XP_040515068.1  GRAM domain-containing protein 4 isoform X6

      UniProtKB/TrEMBL
      A0A8V0XZ39
      Conserved Domains (3) summary
      COG4372
      Location:102 → 251
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      PRK09510
      Location:122 → 184
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      cd13221
      Location:487 → 592
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain

    6. XM_046908714.1 → XP_046764670.1  GRAM domain-containing protein 4 isoform X9

      UniProtKB/TrEMBL
      A0A8V0XZ39

    7. XM_040659136.2 → XP_040515070.1  GRAM domain-containing protein 4 isoform X9

      UniProtKB/TrEMBL
      A0A8V0XZ39
      Conserved Domains (4) summary
      COG4372
      Location:76 → 225
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      PRK09510
      Location:96 → 158
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      cd13221
      Location:479 → 584
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam08372
      Location:305 → 385
      PRT_C; Plant phosphoribosyltransferase C-terminal

    8. XM_046908715.1 → XP_046764671.1  GRAM domain-containing protein 4 isoform X9

      UniProtKB/TrEMBL
      A0A8V0XZ39

    9. XM_046908711.1 → XP_046764667.1  GRAM domain-containing protein 4 isoform X5

      UniProtKB/TrEMBL
      A0A8V0XZ39

    10. XM_046908716.1 → XP_046764672.1  GRAM domain-containing protein 4 isoform X10

      UniProtKB/TrEMBL
      A0A8V0XZ39

    11. XM_040659131.2 → XP_040515065.1  GRAM domain-containing protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XZ39
      Conserved Domains (4) summary
      COG4372
      Location:101 → 250
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      PRK09510
      Location:121 → 183
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      cd13221
      Location:504 → 609
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam08372
      Location:330 → 410
      PRT_C; Plant phosphoribosyltransferase C-terminal

    12. XM_046908712.1 → XP_046764668.1  GRAM domain-containing protein 4 isoform X7

      UniProtKB/TrEMBL
      A0A8V0XZ39, A0A8V0Y0X9
    Nucleotide Protein
    Heading Accession and Version

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