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    CG12054 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43694, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12054provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039831
    Locus tag
    Dmel_CG12054
    See related
    AllianceGenome:FB:FBgn0039831
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12054
    Summary
    Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in embryonic brain; embryonic/larval midgut; larval nervous system; larval ventral nerve cord; and organism. Orthologous to human JAZF1 (JAZF zinc finger 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12054 in Genome Data Viewer
    Location:
    100B8-100B8; 3-102 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31220702..31231259)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (27046424..27056981)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene ATP synthase, subunit C Neighboring gene Ribonuclease P RNA Neighboring gene mir-4949 stem loop Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Predicting gene regulatory interactions based on spatial gene expression data and deep learning. Yang Y, et al. PLoS Comput Biol, 2019 Sep. PMID 31527870, Free PMC Article
    2. Interplay of dFOXO and two ETS-family transcription factors determines lifespan in Drosophila melanogaster. Alic N, et al. PLoS Genet, 2014 Sep. PMID 25232726, Free PMC Article
    3. Genome-wide identification of hypoxia-induced enhancer regions. Kamps-Hughes N, et al. PeerJ, 2015. PMID 26713262, Free PMC Article
    4. Drosophila SWR1 and NuA4 complexes are defined by DOMINO isoforms. Scacchetti A, et al. Elife, 2020 May 20. PMID 32432549, Free PMC Article
    5. Maternally Inherited Stable Intronic Sequence RNA Triggers a Self-Reinforcing Feedback Loop during Development. Tay ML, et al. Curr Biol, 2017 Apr 3. PMID 28343963

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12054-PA
    CG12054-PB
    CG12054-PE
    CG12054-PF

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      31220702..31231259
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001260456.2 → NP_001247385.2  uncharacterized protein Dmel_CG12054, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247385.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K810
      Conserved Domains (2) summary
      COG5189
      Location:123 → 231
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:176 → 196
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. NM_001260457.2 → NP_001247386.2  uncharacterized protein Dmel_CG12054, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247386.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K810
      Conserved Domains (2) summary
      COG5189
      Location:123 → 231
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:176 → 196
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. NM_143596.3 → NP_651853.1  uncharacterized protein Dmel_CG12054, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651853.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q960L0, Q9V9Z6
      Related
      FBpp0085120
      Conserved Domains (1) summary
      COG5189
      Location:123 → 231
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]

    4. NM_170545.3 → NP_733424.2  uncharacterized protein Dmel_CG12054, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733424.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IHE2
      Conserved Domains (1) summary
      COG5189
      Location:13 → 121
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4K810 A0A0B4K810
    Q8IHE2 Q8IHE2
    Q9V9Z6 Q9V9Z6

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