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    murP N-acetylmuramic acid-specific PTS enzyme IICB component/anhydro-N-acetylmuramic acid transporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946894, updated on 17-Dec-2024

    Summary

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    Official Symbol
    murP
    Official Full Name
    N-acetylmuramic acid-specific PTS enzyme IICB component/anhydro-N-acetylmuramic acid transporter
    Primary source
    ECOCYC:G7264
    Locus tag
    b2429
    See related
    ASAP:ABE-0008009
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2424; yfeV
    Summary
    MurP contains only EIIBC domains. [More information is available at EcoGene: EG14163]. MurP contains PTS Enzyme IIBC domains of the N-acetylmuramic acid PTS transporter. [More information is available at EcoCyc: G7264].
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    Genomic context

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    Sequence:
    NC_000913.3 (2546673..2548097)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator MurR Neighboring gene N-acetylmuramic acid 6-phosphate etherase Neighboring gene penicillin binding protein 4B Neighboring gene porphyrinogen peroxidase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The transcriptional factors MurR and catabolite activator protein regulate N-acetylmuramic acid catabolism in Escherichia coli. Jaeger T, et al. J Bacteriol, 2008 Oct. PMID 18723630, Free PMC Article
    2. Identification of a phosphotransferase system of Escherichia coli required for growth on N-acetylmuramic acid. Dahl U, et al. J Bacteriol, 2004 Apr. PMID 15060041, Free PMC Article
    3. Prediction of lipoprotein signal peptides in Gram-negative bacteria. Juncker AS, et al. Protein Sci, 2003 Aug. PMID 12876315, Free PMC Article
    4. Fine-tuning the prediction of sequences cleaved by signal peptidase II: a curated set of proven and predicted lipoproteins of Escherichia coli K-12. Gonnet P, et al. Proteomics, 2004 Jun. PMID 15174130
    5. TCDB: the Transporter Classification Database for membrane transport protein analyses and information. Saier MH Jr, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381841, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-N(PI)-phosphohistidine-sugar phosphotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within carbohydrate transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    N-acetylmuramic acid-specific PTS enzyme IICB component/anhydro-N-acetylmuramic acid transporter
    NP_416924.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2546673..2548097
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416924.1 N-acetylmuramic acid-specific PTS enzyme IICB component/anhydro-N-acetylmuramic acid transporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416924.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8H9SYC6
      Conserved Domains (1) summary
      PRK09586
      Location:2 → 474
      murP; PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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