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    Zfp2 zinc finger protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 497897, updated on 9-Dec-2024

    Summary

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    Symbol
    Zfp2provided by RGD
    Full Name
    zinc finger protein 2provided by RGD
    Primary source
    RGD:1562610
    See related
    EnsemblRapid:ENSRNOG00000030750 AllianceGenome:RGD:1562610
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Mkr2; Mkr-2
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZFP2 (ZFP2 zinc finger protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 90.8), Kidney (RPKM 49.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp2 in Genome Data Viewer
    Location:
    10q22
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (35701303..35729861, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (35209187..35228849, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (36388136..36406721, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene glutamate metabotropic receptor 6 Neighboring gene zinc finger protein 454 Neighboring gene zinc finger protein 354B Neighboring gene uncharacterized LOC134480687

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of zinc finger encoding genes from the tumoral exocrine pancreatic cell line AR42J. Mesa K, et al. Cancer Lett, 1996 Jun 5. PMID 8635150
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein ZFP2
    Names
    multifinger protein mKr2
    zinc finger protein 2 homolog
    zinc finger protein 879-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127558.1 → NP_001121030.1  zinc finger protein ZFP2

      See identical proteins and their annotated locations for NP_001121030.1

      Status: PROVISIONAL

      Source sequence(s)
      BC161925
      UniProtKB/TrEMBL
      A0A8I6A0G2, B1WBX4
      Related
      ENSRNOP00000110159.1, ENSRNOT00000158635.1
      Conserved Domains (2) summary
      COG5048
      Location:76 → 451
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:384 → 404
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      35701303..35729861 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063269599.1 → XP_063125669.1  zinc finger protein ZFP2 isoform X2

    2. XM_063269601.1 → XP_063125671.1  zinc finger protein ZFP2 isoform X2

    3. XM_063269603.1 → XP_063125673.1  zinc finger protein ZFP2 isoform X2

    4. XM_063269602.1 → XP_063125672.1  zinc finger protein ZFP2 isoform X2

    5. XM_063269598.1 → XP_063125668.1  zinc finger protein ZFP2 isoform X2

    6. XM_063269600.1 → XP_063125670.1  zinc finger protein ZFP2 isoform X2

    7. XM_063269597.1 → XP_063125667.1  zinc finger protein ZFP2 isoform X2

    8. XM_039086551.1 → XP_038942479.1  zinc finger protein ZFP2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A0G2, B1WBX4
      Related
      ENSRNOP00000108026.1, ENSRNOT00000121510.1
      Conserved Domains (2) summary
      COG5048
      Location:76 → 451
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:384 → 404
      ZF_C2H2; C2H2 Zn finger [structural motif]

    9. XM_039086549.2 → XP_038942477.1  zinc finger protein ZFP2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A0G2, B1WBX4
      Related
      ENSRNOP00000102842.1, ENSRNOT00000144069.1
      Conserved Domains (2) summary
      COG5048
      Location:76 → 451
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:384 → 404
      ZF_C2H2; C2H2 Zn finger [structural motif]

    10. XM_039086558.1 → XP_038942486.1  zinc finger protein ZFP2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A0G2, B1WBX4
      Conserved Domains (2) summary
      COG5048
      Location:76 → 451
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:384 → 404
      ZF_C2H2; C2H2 Zn finger [structural motif]

    11. XM_039086554.1 → XP_038942482.1  zinc finger protein ZFP2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A0G2, B1WBX4
      Conserved Domains (2) summary
      COG5048
      Location:76 → 451
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:384 → 404
      ZF_C2H2; C2H2 Zn finger [structural motif]

    12. XM_039086556.1 → XP_038942484.1  zinc finger protein ZFP2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A0G2, B1WBX4
      Conserved Domains (2) summary
      COG5048
      Location:76 → 451
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:384 → 404
      ZF_C2H2; C2H2 Zn finger [structural motif]

    13. XM_039086555.1 → XP_038942483.1  zinc finger protein ZFP2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A0G2, B1WBX4
      Related
      ENSRNOP00000105741.1, ENSRNOT00000155915.1
      Conserved Domains (2) summary
      COG5048
      Location:76 → 451
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:384 → 404
      ZF_C2H2; C2H2 Zn finger [structural motif]

    14. XM_039086552.1 → XP_038942480.1  zinc finger protein ZFP2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A0G2, B1WBX4
      Related
      ENSRNOP00000088741.1, ENSRNOT00000114612.2
      Conserved Domains (2) summary
      COG5048
      Location:76 → 451
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:384 → 404
      ZF_C2H2; C2H2 Zn finger [structural motif]

    15. XM_039086557.1 → XP_038942485.1  zinc finger protein ZFP2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A0G2, B1WBX4
      Conserved Domains (2) summary
      COG5048
      Location:76 → 451
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:384 → 404
      ZF_C2H2; C2H2 Zn finger [structural motif]

    16. XM_039086553.1 → XP_038942481.1  zinc finger protein ZFP2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A0G2, B1WBX4
      Related
      ENSRNOP00000041481.2, ENSRNOT00000040346.4
      Conserved Domains (2) summary
      COG5048
      Location:76 → 451
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:384 → 404
      ZF_C2H2; C2H2 Zn finger [structural motif]

    17. XM_063269595.1 → XP_063125665.1  zinc finger protein ZFP2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A0G2, B1WBX4
      Related
      ENSRNOP00000085038.1, ENSRNOT00000102165.2

    18. XM_039086550.2 → XP_038942478.1  zinc finger protein ZFP2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A0G2, B1WBX4
      Conserved Domains (2) summary
      COG5048
      Location:76 → 451
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:384 → 404
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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