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    Fam184a family with sequence similarity 184, member A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361853, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fam184aprovided by RGD
    Official Full Name
    family with sequence similarity 184, member Aprovided by RGD
    Primary source
    RGD:1311294
    See related
    EnsemblRapid:ENSRNOG00000026407 AllianceGenome:RGD:1311294
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311294; Fam184a-ps1
    Summary
    Predicted to be located in P-body and centriolar satellite. Orthologous to human FAM184A (family with sequence similarity 184 member A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 64.4), Brain (RPKM 47.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fam184a in Genome Data Viewer
    Location:
    20q11
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (33477089..33599296, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (32934424..33056626, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (34935029..35054806, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene NADH:ubiquinone oxidoreductase subunit B4, pseudogene 9 Neighboring gene minichromosome maintenance 9 homologous recombination repair factor Neighboring gene anti-silencing function 1A histone chaperone Neighboring gene minichromosome maintenance 9 homologous recombination repair factor like Neighboring gene small nucleolar RNA SNORA26 Neighboring gene uncharacterized LOC120098964 Neighboring gene mannosidase, alpha, class 1A, member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach. Böhm D, et al. Oncol Rep, 2012 Aug. PMID 22664934, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in P-body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM184A
    Names
    family with sequence similarity 184, member A, pseudogene 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427095.1 → NP_001414024.1  protein FAM184A

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020
      UniProtKB/TrEMBL
      A0A8I5ZWH8, F1LW90
      Related
      ENSRNOP00000000475.9, ENSRNOT00000000475.9

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      33477089..33599296 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063279315.1 → XP_063135385.1  protein FAM184A isoform X14

      UniProtKB/TrEMBL
      A6K499

    2. XM_039099322.2 → XP_038955250.1  protein FAM184A isoform X13

      UniProtKB/TrEMBL
      A6K499
      Conserved Domains (2) summary
      COG1196
      Location:47 → 314
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:129 → 529
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    3. XM_063279314.1 → XP_063135384.1  protein FAM184A isoform X11

      UniProtKB/TrEMBL
      A0A8I6AX05

    4. XM_039099319.2 → XP_038955247.1  protein FAM184A isoform X9

      UniProtKB/TrEMBL
      A0A8I6AX05
      Related
      ENSRNOP00000093426.1, ENSRNOT00000109090.2
      Conserved Domains (2) summary
      TIGR02168
      Location:161 → 916
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    5. XM_039099318.2 → XP_038955246.1  protein FAM184A isoform X8

      UniProtKB/TrEMBL
      A0A8I5ZS46
      Related
      ENSRNOP00000092174.2, ENSRNOT00000120309.2
      Conserved Domains (2) summary
      TIGR02168
      Location:226 → 959
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    6. XM_039099315.2 → XP_038955243.1  protein FAM184A isoform X5

      UniProtKB/TrEMBL
      A0A8I5ZWH8, A0A8I6AHN2
      Conserved Domains (2) summary
      TIGR02168
      Location:226 → 959
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    7. XM_063279312.1 → XP_063135382.1  protein FAM184A isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZS46

    8. XM_039099321.2 → XP_038955249.1  protein FAM184A isoform X12

      UniProtKB/TrEMBL
      A0A8I6A0I8
      Conserved Domains (2) summary
      TIGR02168
      Location:226 → 973
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    9. XM_039099316.2 → XP_038955244.1  protein FAM184A isoform X6

      UniProtKB/TrEMBL
      A0A8I5ZS46
      Conserved Domains (2) summary
      TIGR02168
      Location:226 → 973
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    10. XM_039099314.2 → XP_038955242.1  protein FAM184A isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZWH8
      Conserved Domains (2) summary
      TIGR02168
      Location:226 → 973
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    11. XM_039099313.2 → XP_038955241.1  protein FAM184A isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZS46
      Related
      ENSRNOP00000079991.2, ENSRNOT00000109149.2
      Conserved Domains (2) summary
      TIGR02168
      Location:226 → 1022
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    12. XM_008773015.3 → XP_008771237.2  protein FAM184A isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZWH8
      Conserved Domains (2) summary
      TIGR02168
      Location:226 → 1022
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    13. XM_039099317.2 → XP_038955245.1  protein FAM184A isoform X7

      UniProtKB/TrEMBL
      A0A8I6A0I8
      Conserved Domains (2) summary
      TIGR02168
      Location:226 → 1022
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    14. XM_039099323.2 → XP_038955251.1  protein FAM184A isoform X15

      UniProtKB/TrEMBL
      A6K499
      Conserved Domains (2) summary
      COG1196
      Location:1 → 244
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:59 → 459
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    15. XM_039099320.2 → XP_038955248.1  protein FAM184A isoform X10

      UniProtKB/TrEMBL
      A0A8I6A0I8
      Conserved Domains (2) summary
      TIGR02168
      Location:226 → 995
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    RNA

    1. XR_005497785.2 RNA Sequence

    2. XR_005497786.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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