This SuperSeries is composed of the SubSeries listed below.
Overall design: Refer to individual Series
| Accession | PRJNA826482; GEO: GSE200754 |
| Type | Umbrella project |
| Publications | Chen M et al., "CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins.", Nucleic Acids Res, 2023 Aug 11;51(14):7288-7313 |
| Submission | Registration date: 13-Apr-2022
College of Pharmacy, University of South Carolina |
| Relevance | Superseries |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 123 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 123 |
| GEO DataSets | 7 |
Transcriptomic and Proteomic Effects of CDK8 and CDK19 Mediator Kinases encompasses the following 6 sub-projects:
| Project Type | Number of Projects |
| Transcriptome or Gene expression | 6 |
BioProject
accession | Organism | Title |
|---|
| PRJNA826484 | Homo sapiens | Transcriptomic analysis of the effects of expression of CDK8/CDK19 and their kinase-inactive mutants in HEK293 cells (WT) and their CDK8/19 double-knockout (dKO) derivatives (College of Pharmacy, University...) | | PRJNA819404 | Homo sapiens | Effects of Inhibition of CDK8/19 Mediator Kinase on serum-regulated gene expression in 293 cells (College of Pharmacy, University...) | | PRJNA824878 | Homo sapiens | Effects of inhibition of CDK8/19 mediator kinase on signal-regulated gene expression in 293 cells (treated with PMA for 24 hours) (College of Pharmacy, University...) | | PRJNA826476 | Homo sapiens | Effects of CDK8/19 mediator kinase inhibition by didehydrocortistatin A (dCA) and 15w on gene expression in HEK293 cells (College of Pharmacy, University...) | | PRJNA826456 | Homo sapiens | Effects of CDK8/19 mediator kinase inhibition by Senexin B in HAP-1 cells treated with or without interferon-gamma (College of Pharmacy, University...) |
List all 6 'Transcriptome or Gene expression' projects...BioProject
accession | Organism | Title |
|---|
| PRJNA826484 | Homo sapiens | Transcriptomic analysis of the effects of expression of CDK8/CDK19 and their kinase-inactive mutants in HEK293 cells (WT) and their CDK8/19 double-knockout (dKO) derivatives (College of Pharmacy, University...) | | PRJNA819404 | Homo sapiens | Effects of Inhibition of CDK8/19 Mediator Kinase on serum-regulated gene expression in 293 cells (College of Pharmacy, University...) | | PRJNA824878 | Homo sapiens | Effects of inhibition of CDK8/19 mediator kinase on signal-regulated gene expression in 293 cells (treated with PMA for 24 hours) (College of Pharmacy, University...) | | PRJNA826476 | Homo sapiens | Effects of CDK8/19 mediator kinase inhibition by didehydrocortistatin A (dCA) and 15w on gene expression in HEK293 cells (College of Pharmacy, University...) | | PRJNA826456 | Homo sapiens | Effects of CDK8/19 mediator kinase inhibition by Senexin B in HAP-1 cells treated with or without interferon-gamma (College of Pharmacy, University...) | | PRJNA826446 | Homo sapiens | Effects of inhibition of CDK8/19 mediator kinase on signal-regulated gene expression in 293 cells (treated with PMA for 2 hours) (College of Pharmacy, University...) |
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