Conserved Protein Domain Family
Gp3-like

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pfam18897: Gp3-like 
Recombination directionality factor-like
This entry includes Gp3 from Streptomyces phage phiC31. Gp3 is a recombination directionality factor that interacts directly with the integrase tetramer to activate excision and inhibit integration. The characteriztics of the protein distribution suggest prophage matches in addition to the phage matches.
Statistics
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PSSM-Id: 408667
Aligned: 39 rows
Threshold Bit Score: 98.226
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_035942891  26 IGKIRPGIKVLTRAAQsneqavklysemvaagdsfdtigqvietrckirnplVPKNTSYFTCRRSdfsnpdtadeILKLY 105 Caballeronia gl...
Q6VY80        15 LGRIRTGYSRPSSKPGnr---------------------------------rVPVRSETFLLSSHsrty---ierAAELY 58  Streptomyces ph...
YP_009213176  15 LGRIRTGYTRPNPNPDrg---------------------------------pIPVKSKTFVLSSHsrdy---vaaAAELY 58 
SDL33808      15 LGRIRTGYSRPHSDPNkr---------------------------------pVPVKSKTFVLSSHsrdy---vaaAAELY 58 
WP_054050642  13 AGRIRIGQQVPTGKGGs-----------------------------------RPEKLTTFRLTSSdahr---iqlAAQMF 54  Alloactinosynne...
BAL87359      18 VGVIRLGQQLISKKSGk----------------------------------pFPSKLETLRFTSPskpl---idaVAAAY 60 
WP_069464230  13 LGEIRIGRVVDTGRVSertg----------------------------kailRPEKLKAFRFTSPskei---leqVATLY 61  Streptomyces ru...
WP_038679405  13 LGRIRLGQKQAFTRRDgse-------------------------------gvKPVKLDRFRLTSAskpl---lekVAELY 58  Pimelobacter si...
GAW50582      15 LGRIRLGAKRDGSGA--------------------------------------PMKLASFRFTSPseqy---ikdLAELY 53 
AFM54825      20 VGQIKTGFKNDr---------------------------------------gYPQSCDYFIPAGKya------glFKQAY 54 
WP_035942891 106 GEDRedg-------------rklFRFPVMFAFDDWLRNVPNQMAVYGTSgrqYFSEYGPDGR-RYCKtyapverdpraqr 171 Caballeronia gl...
Q6VY80        59 GGEPeawtpqgskieqfrviteaRELYSILPPGD---PLSQANELWTGGgcaRRC----DGVtEQLTrkp---------- 121 Streptomyces ph...
YP_009213176  59 GGRVeewtpqnqsvaqfrvitdaSELRAILPAGD---PLSQSYEMWSGGgcsRRC----DGEtEQLTrrp---------- 121
SDL33808      59 GGRVeewtpqnqsvaqfrviteaSELRAILPQGD---PLSQSYEMWSGGgcaRRC----DGEtEQLTrrp---------- 121
WP_054050642  55 GGQAapwqapagp--qwevvtdaDALEVIVPPSD--MAFSQHYELWSAGgcqRRC----DGRvESISdga---------- 116 Alloactinosynne...
BAL87359      61 GGEVkkwdsptgv--qwevitgaKEIPVLVPPQR----IDPNLEHWGNGfrdRMC----DGDvEKIRqqp---------- 120
WP_069464230  62 GGEVqpwtpanggpdefevysdaTRLPVLIPPRD---SVSQWYEHYQGSkcvRRC----DGQvEQKSdrp---------- 124 Streptomyces ru...
WP_038679405  59 GGDVaewtppggs-pqwevvtasARLPIMVPPQP----VTQWYETWSRAgcqHRC----DGQhNVLT------------- 116 Pimelobacter si...
GAW50582      54 GGEArpwdnggkp--efevfteaSTIDVIAVKGG----LSQWMETWSGGgcvHRC----DGEvNTLT------------- 110
AFM54825      55 GDKP-------------------DTVQVVFWEDTPETMCNERYELRDKDg---KLYARGDGEeFEIWh------------ 100
WP_035942891 172 arrsfggrmvihrqdddipdGICDph--aCPQYQ-----------DRKC------------NLSATFFFVIPEIKG-LGL 225 Caballeronia gl...
Q6VY80       122 ---------------------------clCLAEHgegwh--eqpaGTVC------------KPTSRIAVMLADMPD-LGV 159 Streptomyces ph...
YP_009213176 122 ---------------------------clCLAQYgddwh--lrsaREVC------------RPTSRINVMLPDLPD-LGV 159
SDL33808     122 ---------------------------clCFAQYgddwh--lrsaREVC------------KPTSRINVMLPDLPD-LGV 159
WP_054050642 117 ---------------------------cvCDPD------------AREC------------DIHTRLSVMLRDLPG-LGV 144 Alloactinosynne...
BAL87359     121 ---------------------------chCAAAQlagr---pfgpRDIC------------KPTTRMALMLADIPS-LGT 157
WP_069464230 125 ---------------------------cmCNPD------------RRMC------------KITTRVNVMLRDVAA-LGQ 152 Streptomyces ru...
WP_038679405 117 ---------------------------------------------DEPCdpddpqhiealkKPTTRLNVVLRDVEG-IGV 150 Pimelobacter si...
GAW50582     111 ---------------------------------------------NQACnpndp--ahknaKPTTRLSLMLPELEA-MGV 142
AFM54825     101 -------------------tGSQQyktytATEYPdimertkkqvgAKEW------------EVILTLRFIMPKVKDiAGY 149
WP_035942891 226 IELPTNSI-YVLQKAYSAMQTVSLAR-GRLTGT--RFWLSKREFEIMR-IDetgqpk-rqkqmlTVLDADIDLS 293 Caballeronia glathei
Q6VY80       160 WRLESHSW-YAADAMAGGIDMVLAATdGK-SPMplRMWIEQRQ-------Vkrrg------etkNFPVVMVVPA 218 Streptomyces phage VWB
YP_009213176 160 WRLESKSY-YAADAMAGGLDIVLAATeGR-SMMpvRMWIEQRT-------Rvang------ktkQFPVVMVVPS 218
SDL33808     160 WRLESKSY-YAADAMAGGIDTVLAATeGR-SMMpvRMWIEQRT-------Rvang------ktkNFPVVMVVPS 218
WP_054050642 145 WRIDTQGY-YAAVELQGAVEVIQIAA-GRGQMLpaRLRLEQRVVKRPGvGTr------------RFAVPVLDVE 204 Alloactinosynnema sp....
BAL87359     158 WKLESHGW-NAAAELPTLAASIESAP----QPIpaRLEVQKREKKDFD-PSkgdge---qveskVFMVPVLHFD 222
WP_069464230 153 WLLISKGY-YAAVELPPAAELLAQVG----GYVqgWLGMEEKLVVREDgPT-------------RFMVPTLDVE 208 Streptomyces rubidus
WP_038679405 151 WRVETHGW-NAALELPDVAEFLAQAG----GYVngWLALEQRT-------SvgrnestgqpetrHYMVPIIEID 212 Pimelobacter simplex
GAW50582     143 WRMESHGW-NAAAEIPAVAELALFVG----DLVpaVLHMVERR-------Svrdg------ktsRFVVPVLDLR 198
AFM54825     150 WEFSTKGEaSTIPAIRDTFDMMMQQR-GSVRGVifDLSVKFAKSQKPGvKS-------------RYPVVSLVPN 209
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