GEO DataSets

(Submitter supplied) It has been proposed that endogenously formed N-nitroso compounds (NOCs) are partly responsible for the link between red meat consumption and colorectal cancer (CRC) risk. As nitrite has been indicated as one of the critical factors in the formation of endogenous NOCs, it is of high importance to replace or reduce the nitrite levels in meat. Therefore, the PHYTOME project was initiated (Phytochemicals to reduce nitrite in meat products; www.phytome.eu), an EU funded research project aiming to develop innovative meat products in which the food additive sodium nitrite (E251) has been replaced by natural compounds originating from fruits and vegetables. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL21061

216 Samples

Download data: TXT

(Submitter supplied) The gene expression profile of various cell signaling pathway associated genes were compared between the controls and haze predisposed groups

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL21061

2 Samples

Download data: TXT

(Submitter supplied) To further investigating the novel NGS-defined HCC-associated SNVs in small S region involve hepatocarcinogenesis pathways, the plasmid pEGFP-N1-HBVS-genoB was used as the template for mutagenesis to create mutations T216C, A273G, and double mutant T216C/A273G at small surface (S) region, with the QuikChange site-directed mutagenesis kit (Stratagene, La Jolla, CA). The plasmid pEGFP-N1-HBVS-genoC was used as the template for mutagenesis to create mutations A293G, C446G, A456G, A293G/C446G, C446G/A456G, A293G/A456G, and triple mutant A293G/C446G/A456G at small S region. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL21061

12 Samples

Download data: TXT

(Submitter supplied) Gene expression analysis of MDA-MB-231 breast cancer cells cultured in attached (treated with vehicle DMSO or A76) or suspension (and stably expressing control shRNA or shAMPKα2). Results provide insights into changes in molecular pathways and its regulation by AMPK

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL21061

8 Samples

Download data: TXT

(Submitter supplied) Chromobox (CBX) family proteins are components in polycomb repressive complex 1 (PRC1), responsible for targeting PRC1 to the chromatin. We studied genes regulated by CBX6, 7, or 8 in human ACC-Meso-4 mesothelioma cell line by microarray analysis of ACC-Meso-4 cells stably expressing short hairpin RNA (shRNA) targeting CBX-6, 7, 8, or control nontarget shRNA.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL21061

8 Samples

Download data: TXT

(Submitter supplied) To determine the target genes of RBM10,we have employed microarray based gene expression profiling by knocking down RBM10 in HEK 293 cells. Microarray analysis after RBM10 knockdown on HEK 293 cells showed that over 1000 genes were down regulated while another 800 genes up regulated as a result of the knockdown. Among the down regulated genes, we found the significant presence of cardiovascular disease related genes, especially cardiac hypertrophy and heart failure. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL21061

6 Samples

Download data: TXT, XLS

(Submitter supplied) To understand the host response of C. glabrata, we have employed the whole genome microarray expression profiling to identify the differentially regulated genes. For this, differentiated THP-1 cells were infected with C. glabrata wt, Cgvps34Δ and Cgyps(1-11)Δ cells for 6 h. Uninfected THP-1 cells, treated with PBS were taken as control. Total RNA was extracted using TriZol Reagent followed by ethonol precipitation. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL21061

8 Samples

Download data: TXT

(Submitter supplied) This microarray experiment was performed for identifying the signaling pathways that could be differentially regulated in response to changes in the pigmentation levels in human melanocytes. Melanocytes were either treated with pigmentation inducing agent or depigmenting compound targeting tyrosinase (key enzyme involved in the melanogenesis). The samples were then processed for analyzing the differentially regulated signaling pathway by performing microarray on agilent platform. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL21061

3 Samples

Download data: TXT, XLSX

(Submitter supplied) Gene expression analysis of patient metastatic tumor derived cell lines.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL21061

9 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array; Genome variation profiling by genome tiling array

Platforms:

GPL22194 GPL21061

15 Samples

Download data: BW, JPG, PDF, TIFF, TXT

(Submitter supplied) Comparison of copy number variations and gene expression profiles of cell lines obtained from the primary and lymph node metastatic tumors from a single patient.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL21061

4 Samples

Download data: JPG, PDF, TIFF, TXT

(Submitter supplied) H1299 cells (p53-/-) were transfected with plasmid constructs expressing p53 alone, p47 alone or both, and gene expression profile was probed

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL21061

8 Samples

Download data: TXT

(Submitter supplied) Differential expression study of lncRNAs (long non-coding RNAs) and mRNAs in HCV infection. For this we infected Huh7.5 cells with HCV (JFH-1) virus and control cells were mock infected. 48h post infection we isolated total RNA using qiagen RNeasy kit as per manufacturer's protocol. The total RNA was then subjected to microarray for both lncRNAs and mRNAs. The resultant profile can be used to compare gene expression in HCV infection versus mock infected cells.

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platform:

GPL21061

4 Samples

Download data: TXT