GSE12738[Accession] - GEO DataSets

Select item 2000127381.

Expression data from Pseudomonas aeruginosa exposed to a low concentration of Azithromycin

(Submitter supplied) Low-dose macrolides are effective therapy in patients with chronic lung infections, but the mechanisms of action are unclear. We compared global gene expression profiles between P.aeruginosa with and without low-dose Azithromycin (AZM) to study why the low-dose macrolide therapy is effective for cystic fibrosis and diffuse panbronchiolitis. Keywords: dose-response

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array

Dataset:: GDS3562
Platform:: GPL84
5 Samples

Download data: CEL

Series

Accession:: GSE12738

ID:: 200012738

Select item 35622.

Azithromycin effect on Pseudomonas aeruginosa PAO1

Analysis of PAO1 cultures exposed to up to 2.0 ug/ml of the macrolide azithromycin (AZM) for 9 hours. Low-dose macrolides are effective therapy in patients with chronic lung infections such as those caused by P. aeruginosa. Results provide insight into mechanism of action of AZM against infection.

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by array, count, 2 agent, 3 dose sets

Platform:: GPL84
Series:: GSE12738
5 Samples

Download data: CEL

DataSet

Accession:: GDS3562

ID:: 3562

Select item 1000000843.

[Pae_G1a] Affymetrix Pseudomonas aeruginosa Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html This GeneChip probe array is a powerful tool for monitoring trascriptional regulation and antimicrobial agent response of P. aeruginosa. The array represents the annotated genome of P. aeruginosa strain PA01 and includes 5,549 protein-coding sequences, 18 tRNA genes, a representative of the ribosomal RNA cluster and 117 genes present in strains other than PA01. more...