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Items: 4

1.

Selective Mediator dependence of cell-type-specifying transcription

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Other; Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
125 Samples
Download data: BW, HIC, NARROWPEAK
Series
Accession:
GSE139468
ID:
200139468
2.

Selective Mediator-dependence of cell type-specifying transcription [4C-seq]

(Submitter supplied) The Mediator complex directs signals from DNA-binding transcription factors to RNA polymerase (Pol) II. Despite this pivotal position, mechanistic understanding of Mediator in human cells remains incomplete. Here, we quantified Mediator-controlled Pol II kinetics by coupling rapid subunit degradation with orthogonal experimental readouts. Consistent with a model of condensate-driven transcription initiation, large clusters of hypo-phosphorylated Pol II rapidly disassembled upon Mediator degradation. more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL18573
12 Samples
Download data: BW
Series
Accession:
GSE139464
ID:
200139464
3.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
4.

SATB1-SE_4C-seq_MED14-dTAG_2h_dTAG7_B

Organism:
Homo sapiens
Source name:
SATB1-SE_4C-seq_MED14-dTAG_2h_dTAG7
Platform:
GPL18573
Series:
GSE139464 GSE139468
Download data: BW
Sample
Accession:
GSM4142025
ID:
304142025
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Supplemental Content

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