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Links from GEO DataSets

Items: 1 to 20 of 263

1.
Full record GDS638

Dystrophin-deficient mdx diaphram muscle development time course

Temporal analysis of diaphram muscle from dystrophin-deficient mdx mice, a Duchenne muscular dystrophy (DMD) model. Postnatal ages 7 to 112 days examined. Results provide insight into mechanisms of muscular dystrophy pathogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 6 age, 2 strain sets
Platform:
GPL81
Series:
GSE1026
36 Samples
Download data: CEL
DataSet
Accession:
GDS638
ID:
638
2.
Full record GDS5526

Bile duct ligation effect on the liver

Analysis of livers of animals following bile duct ligation to induce extrahepatic cholestasis. Biliary tract obstruction is a common mechanism of hepatic injury. Results provide insight into molecular mechanisms that influence injury and repair in cholestatic liver disease.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL81
Series:
GSE29776
6 Samples
Download data: CEL
DataSet
Accession:
GDS5526
ID:
5526
3.
Full record GDS5423

Circadian modulators SHARP1/SHARP2 deficiency effect on cortex: time course

Analysis of cortex from SHARP1/2 double null mutants at ZT4 (wake phase) and ZT16 (sleep phase). bHLH transcription factors SHARP1 (DEC2, BHLHE41) and SHARP2 (DEC1, BHLHE40) are circadian modulators. Results provide insight into the molecular contributions of SHARP1/SHARP2 to the sleep-wake cycle.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 time sets
Platform:
GPL81
Series:
GSE59941
8 Samples
Download data: CEL
4.
Full record GDS5005

Running effect on hippocampal subgranular zone: time course

Analysis of LCM samples of the subgranular zone (SGZ) of the hippocampal dentate gyrus isolated from adults subjected to running for up to 30 days. The SGZ is a major site of neurogenesis in adult brain. Running enhances SGZ proliferation. Results provide insight into the SGZ molecular environment.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 cell type, 9 individual, 2 protocol, 3 time sets
Platform:
GPL81
Series:
GSE39697
18 Samples
Download data: CEL
5.
Full record GDS4461

Endothelial cells from P8 neonatal retina [MG_U74Av2]

Analysis of FACS-sorted, GFP-positive endothelial cells from retinas of postnatal day 8 (P8) homozygous Tie2-GFP transgenics. Deregulated retinal angiogenesis causes vision loss in many ocular diseases. Results provide insight into the molecular mechanisms underlying intraretinal angiogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 cell type sets
Platform:
GPL81
Series:
GSE27238
6 Samples
Download data: CEL
6.
Full record GDS4140

Proteasomal inhibitor lactacystin effect on cortical neurons in vitro: time course (MG_U74Av2)

Analysis of cultured cortical neurons treated with 1uM lactacystin for up to 48 hr. Lactacystin induces neuronal apoptosis. Results provide insight into molecular mechanisms underlying proteasomal inhibition-induced neuronal death.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 time sets
Platform:
GPL81
Series:
GSE22465
6 Samples
Download data: CEL
DataSet
Accession:
GDS4140
ID:
4140
7.
Full record GDS4024

NOD mice positive for Early Insulin AutoAntibodies: pancreatic lymph nodes

Analysis of pancreatic lymph nodes of Early Insulin AutoAntibodies (E-IAA) positive 5 wk-old Non Obese Diabetic (NOD) mice. E-IAA mark the first measurable phenotypic checkpoint in T1D pathogenesis. Results provide insight into molecular mechanisms underlying initiation of T1D.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL81
Series:
GSE15582
9 Samples
Download data: CEL
8.
Full record GDS4017

Activation of dendritic cells in NOD model of type 1 diabetes: time course

Analysis of therapeutic-GM4 and nontherapeutic-GM bone marrow-derived NOD dendritic cells (DC) up to 20 hrs after activation with LPS + IFN-gamma. The GM4 DC population is able to prevent diabetes in NOD mice. Results provide insight into the molecular basis of the therapeutic effect of GM4 DC.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 cell type, 3 time sets
Platform:
GPL81
Series:
GSE15320
15 Samples
Download data: CEL, CHP
9.
Full record GDS3779

Chromogranin A-null model of hypertension: adrenal gland

Analysis of adrenal glands from 12-week old, chromogranin A knockouts (Chga KO). The Chga KO displays severe hypertension coupled with reduction in size, number, and density of regulated secretory granules. Results provide insight into the molecular basis of this monogenic hypertension model.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL81
Series:
GSE18332
6 Samples
Download data: CEL, CHP
10.
Full record GDS3777

BPH model of hypertension: adrenal gland

Analysis of adrenal glands from genetically/hereditary hypertensive (BPH/2) and genetically/hereditary low-blood pressure (BPL/1) 12-week old adults. Results provide insight into molecular mechanisms underlying the pathogenesis of genetic hypertension.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 strain sets
Platform:
GPL81
Series:
GSE19342
6 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS3777
ID:
3777
11.
Full record GDS3536

Seizure model: brain

Analysis of brains of nicotine-induced seizure-sensitive (alpha7 +/T) and -resistant (beta4 -/-) nicotinic acetylcholine receptor (nAChR) mutants following nicotine treatment. Results provide insight into the molecular mechanisms underlying seizures.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 3 genotype/variation sets
Platform:
GPL81
Series:
GSE6614
28 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS3536
ID:
3536
12.
Full record GDS3508

Hormone-sensitive lipase deficient liver response to a high fat diet

Analysis of livers from hormone-sensitive lipase (HSL) null mutants fed a high fat diet. Decreased hepatic insulin sensitivity and elevation of plasma cholesterol are observed in this HSL-null animal model. Results provide insight into the mechanisms underlying these features.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 protocol sets
Platform:
GPL81
Series:
GSE10067
4 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS3508
ID:
3508
13.
Full record GDS3506

Humanized gnotobiotic mouse model response to foodborne enteropathogen Listeria monocytogenes: ileum

Analysis of ileum from human enterocyte-associated E-cadherin receptor-expressing, germ-free transgenic mice (Fabpi-hEcad) colonized with wildtype L. monocytogenes or mutant strains with inlA, inlB, hly deletions. Results provide insight into host response to invasive foodborne enteropathogens.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 9 infection sets
Platform:
GPL81
Series:
GSE7013
20 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS3506
ID:
3506
14.
Full record GDS3488

Adipose tissue response to dihydrotestosterone: time course

Analysis of retroperitoneal adipose tissue samples from gonadectomized males and females following treatment with dihydrotestosterone (DHT) for up to 24 hours. Results provide insight into the role of DHT in the adipogenesis that occurs in retroperitoneal adipose tissues.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 gender, 7 time sets
Platform:
GPL81
Series:
GSE9631
16 Samples
Download data: CEL
DataSet
Accession:
GDS3488
ID:
3488
15.
Full record GDS3444

Embryonic stem cell response to STAT3 overexpression in vitro (MG-U74A)

Analysis of cultured embryonic stem (ES) cells overexpressing the transcription factor STAT3. STAT3 is a downstream target of the LIF signaling cascade. LIF activation maintains ES cells in a pluripotent state. Results provide insight into the role of STAT3 in maintenance of ES cell pluripotency.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL81
Series:
GSE11398
6 Samples
Download data: CEL, CHP
16.
Full record GDS3418

Spleen CD11b+ cells response to Yersinia enterocolitica (Ye) YopH deletion mutant infection in vivo

Analysis of splenic CD11b+ cells from animals infected with wildtype Yersinia enterocolitica (Ye) or a YopH-deficient Ye mutant. YopH is a virulence factor that inhibits phagocytosis of Ye and promotes virulence of Ye. Results provide insight into the molecular basis of YopH-mediated immune evasion.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 dose, 3 infection sets
Platform:
GPL81
Series:
GSE11189
5 Samples
Download data: CEL, CHP
17.
Full record GDS3375

Visual cortex during the critical period for ocular dominance (MG-U74A)

Analysis of visual cortices before the critical period for ocular dominance plasticity opens [postnatal day 14 (P14)], at the peak sensitivity of the critical period (P28), and after the critical period (P60). Results provide insight into the molecular mechanisms associated with the critical period.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 age sets
Platform:
GPL81
Series:
GSE11764
10 Samples
Download data: CEL, CHP
18.
Full record GDS3361

Fibroblast growth factor-23 transgenic model

Analysis of kidneys from C57Bl transgenics expressing human fibroblast growth factor-23 (FGF23). FGF23 is a circulating protein that causes decreased renal inorganic phosphate (Pi) reabsorption. Results provide insight into molecular mechanisms underlying the regulation of Pi homeostasis by FGF23.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 strain sets
Platform:
GPL81
Series:
GSE6979
10 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS3361
ID:
3361
19.
Full record GDS3349

STAT5 depleted pro-B cell line response to IL-3: time course (MG-U74A)

Analysis of STAT5A and STAT5B depleted proB Ba/F3-beta cells stimulated with IL-3 for 0.5 or 2 hours. STAT5A and STAT5B are members of the family of signal transducers and activators of transcription. Results identify IL-3 inducible STAT5 target genes.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 protocol, 3 time sets
Platform:
GPL81
Series:
GSE10389
5 Samples
Download data: CEL, CHP
20.
Full record GDS3210

Airway epithelial cells response to Sendai virus infection in vitro

Analysis of primary culture tracheal epithelial cells following infection with Sendai virus (SeV), a common paramyxovirus.Respiratory paramyxoviral infections are a leading cause of serious respiratory disease. Results provide insight into the role of epithelial cells in antiviral defense.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 infection sets
Platform:
GPL81
Series:
GSE10211
10 Samples
Download data: CEL
DataSet
Accession:
GDS3210
ID:
3210
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