GEO DataSets

(Submitter supplied) Pure cultures of ammonia oxidizing bacterium, Nitrosomonas europaea, are exposed to cyanide in pseudo-steady state batch reactor in presence of ammonia. Nitrosomonas europaea are generally regarded as the most sensitive organism to various inhibitors commonly encountered in the wastewater treatment plants (WWTP). To find stress genes of Nitrosomonas europaea to cyanide known as inhibitor of respiratory process, whole-genome transcript response to cyanide was determined in this research using microarray and qRT-PCR. more...

Organism:

Nitrosomonas europaea

Type:

Expression profiling by array

Platform:

GPL4617

6 Samples

Download data: CEL

(Submitter supplied) Nitrosomonas europaea is a Gram-negative obligate chemolithoautotroph that derives energy for growth through oxidation of ammonia and participates in the process of nitrification in global nitrogen cycling. The physiological, proteomic, and transcriptional responses of N. europaea to zinc stress were studied. The nitrite production rate and ammonia-dependent oxygen uptake rate of the cells exposed to 3.4 uM ZnCl2 decreased about 61 % and 69 % within 30 minutes, respectively. more...

Organism:

Nitrosomonas europaea

Type:

Expression profiling by array

Platform:

GPL4617

6 Samples

Download data: CEL

(Submitter supplied) Heavy metals have been postulated as significant nitrification inhibitor in wastewater treatment plant. The effect of heavy metals such as Cd2+, Cu2+ and Hg2+ to nitrifying bacterium, Nitrosomonas europaea, was studied in pseudo-steady state batch reactor. Under incubation of Nitrosomonas europaea with 1 ?M CdCl2 for 1 hour, transcripts for 66 of 2460 genes were found at high level, yet transcripts of 50 genes were found at low level. more...

Organism:

Nitrosomonas europaea

Type:

Expression profiling by array

Platform:

GPL4617

6 Samples

Download data: CEL

(Submitter supplied) The physiological and transcriptional response of Nitrosomonas europaea biofilms to phenol and toluene was examined and compared to suspended cells. Biofilms were grown in Drip Flow Biofilm Reactors under continuous flow conditions of growth medium containing ammonia as growth substrate. The responses of N. europaea biofilms to the aromatic hydrocarbons phenol and toluene were determined during short-term (3 h) additions of each compound to the biofilms. more...

Organism:

Nitrosomonas europaea ATCC 19718; Nitrosomonas europaea

Type:

Expression profiling by array

Platform:

GPL9484

12 Samples

Download data: PAIR

(Submitter supplied) To further explore the biotoxicity mechanisms of zinc oxide nanoparticles (ZnO NPs) and the recovery strategies of the accordingly impaired Nitrosomonas europaea (N. europaea, ATCC 19718) cells, a genome-sequenced model ammonia-oxidizing bacterium (AOB) commonly detected in the activated sludge of biological wastewater treatment plants, whole-genome microarray analysis was applied to retrieve the induced transcriptional responses, after their physiological and metabolic activities were revealed.

Organism:

Nitrosomonas europaea; Nitrosomonas europaea ATCC 19718

Type:

Expression profiling by array

Platform:

GPL18989

9 Samples

Download data: TXT, XLS

(Submitter supplied) The effects of the aromatic hydrocarbons benzene and toluene on Nitrosomonas europaea, a nitrifying bacterium that plays an important role in the removal of nitrogen from wastewater treatment plants, were studied in batch reactors. Exposure to 20 M toluene and 40 M benzene resulted in a 50% reduction in nitrifying activity after 1 h. However, Affymetrix microarray experiments detected no significant changes in gene expression in toluene exposed cells. more...

Organism:

Nitrosomonas europaea

Type:

Expression profiling by array

Platform:

GPL4617

12 Samples

Download data: CEL

(Submitter supplied) d-serine is naturally present throughout the human body. It is also used as add-on therapy for treatment-refractory schizophrenia. d-Serine interacts with the strychnine-insensitive glycine binding site of NMDA receptor, and this interaction could lead to potentially toxic activity (i.e., excitotoxicity) in brain tissue. The transcriptomic changes that occur in the brain after d-serine exposure have not been fully explored. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS3643

Platform:

GPL1355

24 Samples

Download data: CEL

Analysis of forebrains of animals treated with up to 500 mg/kg D-serine for 96 hours. D-serine is involved in many physiological processes through its interaction with the glycine binding site of the NMDA receptor. Results provide insight into the impact of D-serine exposure on neuronal functions.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent, 6 dose sets

Platform:

GPL1355

Series:

GSE10748

24 Samples

Download data: CEL

(Submitter supplied) Nitrosomonas europaea is a chemolithoautotrophic bacterium that oxidizes ammonia (NH3) to obtain energy for growth on carbon dioxide (CO2), and can also produce nitrous oxide (N2O), a greenhouse gas. We interrogated the growth, physiological, and transcriptome responses of N. europaea to replete (> 5.2 mM) and limited inorganic carbon (IC) provided by either 1.0 mM or 0.2 mM sodium carbonate (Na2CO3) supplemented with atmospheric CO2. more...

Organism:

Nitrosomonas europaea

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20700

9 Samples

Download data: XLSX

(Submitter supplied) In this study, we investigated the transcriptional response of the human isolate L. reuteri ATCC 55730 during sourdough fermentation by using whole-genome microarrays. Significant changes of mRNA levels were found for 101 genes involved in diverse cellular processes, e.g., carbohydrate and energy metabolism, cell envelope biosynthesis, exopolysaccharide production, stress responses, signal transduction and cobalamin biosynthesis. more...

Organism:

Limosilactobacillus reuteri

Type:

Expression profiling by array

Platform:

GPL6366

6 Samples

Download data: GPR

(Submitter supplied) We analyzed the global transcriptional response of N. europaea when exposed to chloromethane (3.2 mM for 1 h). Chloromethane treatment led to down regulation of 175 genes and up regulation of 67 genes. This treatment was less harmful to the cells than chloroform Keywords: stress response, global transcription, toxin-antitoxin genes

Organism:

Nitrosomonas europaea

Type:

Expression profiling by array

Dataset:

GDS2684

Platform:

GPL4617

6 Samples

Download data: CEL

(Submitter supplied) We analyzed the global transcriptional response of N. europaea when exposed to chloroform (7 µM for 1 h). Chloroform led to down regulation of 501 genes and up regulation of 251 genes. These up regulated genes included genes for heat shock proteins, sigmafactors of extracytoplasmic function subfamily and newly identified genes of toxin-antitoxin loci in N. europaea. Our study showed that despite a significant decrease of transcription in response to the stress, N. more...

Organism:

Nitrosomonas europaea

Type:

Expression profiling by array

Dataset:

GDS2685

Platform:

GPL4617

6 Samples

Download data: CEL

Analysis of Nitrosomonas europaea cells treated with the pollutant chloroform. N. europeaea is an ammonia oxidizer. Results provide insight into the molecular response of ammonia oxidizing bacteria to chlorinated aliphatic hydrocarbons.

Organism:

Nitrosomonas europaea

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL4617

Series:

GSE6488

6 Samples

Download data: CEL

Analysis of Nitrosomonas europaea cells treated with the pollutant chloromethane. N. europeaea is an ammonia oxidizer. Results provide insight into the molecular response of ammonia oxidizing bacteria to chlorinated aliphatic hydrocarbons.

Organism:

Nitrosomonas europaea

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL4617

Series:

GSE6594

6 Samples

Download data: CEL

(Submitter supplied) In the present study, we employed Affymetrix Staphylococcus aureus GeneChip arrays to investigate the dynamics of global gene expression profiles during the cellular response of Staphylococcus aureus to triclosan, which involved initial growth inhibition and metabolism. Keywords: Transcriptome study; antimicrobial response; time course

Organism:

Staphylococcus aureus

Type:

Expression profiling by array

Dataset:

GDS2983

Platform:

GPL1339

15 Samples

Download data: CEL

Analysis of Staphylococcus aureus cultures treated for 10 or 60 minutes with 0.05 uM triclosan. At this concentration, the antimicrobial agent caused growth inhibition for about 10 min. Results provide insight into the initial molecular response of Staphylococcus aureus to triclosan.

Organism:

Staphylococcus aureus

Type:

Expression profiling by array, count, 2 agent, 3 time sets

Platform:

GPL1339

Series:

GSE8861

15 Samples

Download data: CEL

(Submitter supplied) Staphylococcus aureus is one of the most important pathogens in humans and animals, multiply resistant strains are increasingly widespread, new agents are needed for the treatment of S. aureus. Rhein, a natural plant product, has potential antimicrobial activity against Staphylococcus aureus. We employed Affymetrix Staphylococcus aureus GeneChipsTM arrays to investigate the global transcriptional profiling of Staphylococcus aureus ATCC25923 treated with rhein. more...

Organism:

Staphylococcus aureus

Type:

Expression profiling by array

Dataset:

GDS2812

Platform:

GPL1339

6 Samples

Download data: CEL

Analysis of Staphylococcus aureus ATCC25923 cultures treated with subinhibitory concentrations of rhein for 45 minutes. Rhein is an antimicrobial agent from rhubarb. Results provide insight into the efficacy of rhein against Staphylococcus aureus.

Organism:

Staphylococcus aureus

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL1339

Series:

GSE8135

6 Samples

Download data: CEL

(Submitter supplied) PURPOSE: Hyperoxia is toxic to photoreceptors, and this toxicity may be important in the progress of retinal dystrophies. This microarray study examines gene expression induced in the C57BL/6J mouse retina by hyperoxia over the 14-day period during which photoreceptors first resist, then succumb to, hyperoxia. METHODS: Young adult C57BL/6J mice were exposed to hyperoxia (75% oxygen) for up to 14 days. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

8 Samples

Download data: CEL, CHP

(Submitter supplied) In order to obtain a global view of energy metabolism pathways of the sulfate-reducer Desulfovibrio vulgaris Hildenborough and the proteins involved therein whole-genome microarrays were used to compare the transcriptional response of cells grown with hydrogen/sulfate, pyruvate/sulfate, lactate/thiosulfate, and pyruvate with limiting sulfate, relative to growth in standard lactate/sulfate condition. more...

Organism:

Nitratidesulfovibrio vulgaris str. Hildenborough

Type:

Expression profiling by array

Platform:

GPL4071

7 Samples

Download data: TXT