Similar studies for GEO DataSets (Select 200022628) - GEO DataSets

Select item 2000226281.

Deinococcus radiodurans R1: wildtype strains vs. DR1790-deletion strains

(Submitter supplied) Transcriptional profiling of comparing wildtype strains with DR1790-deletion strains under normal growth contidions. Keywords: Genetic modification

Organism:: Deinococcus radiodurans

Type:: Expression profiling by array

Platform:: GPL9466
1 Sample

Download data: GPR

Series

Accession:: GSE22628

ID:: 200022628

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000177242.

Microarray studies of pqqE disruption mutant vs wild type

(Submitter supplied) This bacterial genome encodes pyrroloquinoline quinone (PQQ) synthase enzyme required for the synthesis of PQQ in bacteria. The gene pqqE encoding PQQ synthase was annotated in Deinococcus radiodurans R1 genome and synthesis of PQQ was shown in this bacterium. PQQ roles as an antioxidant and as an inducer of protein kinase in bacterial system was shown. The pqqE disuption mutant showed several folds decrease in gamma radiation tolerance of wild type cells and strong impairment of DSB repair. more...

Organism:: Deinococcus radiodurans; Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

Type:: Expression profiling by array

Platform:: GPL8947
2 Samples

Download data: GPR

Series

Accession:: GSE17724

ID:: 200017724

Select item 2000177223.

Microarray studies of dr2518 knockout mutant vs wild type

(Submitter supplied) Bacterial cells lacking pyrroloquinoline quinone (PQQ) were sensitive to gamma radiation as compared to wild type cells. Deinococcus radiodurans genome encode for five putative PQQ binding STK domain-containing proteins. The comparison of gamma radiation response of all five-deletion mutants with wild type suggested that dr2518 mutant was hypersensitive to gamma radiation as compared to wild type and other mutants. more...

Organism:: Deinococcus radiodurans; Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

Type:: Expression profiling by array

Platform:: GPL8947
2 Samples

Download data: GPR

Series

Accession:: GSE17722

ID:: 200017722

Select item 2001762074.

A small RNA regulates pprM, a modulator of pleiotropic proteins promoting DNA repair, in Deinococcus radiodurans under ionizing radiation

(Submitter supplied) This study explores the regulatory network of a sRNA named PprS (previously Dsr2) in Deinococcus radiodurans R1. We compared the transcriptomes of two strains with and without exposure to 10 kGy acute ionizing radiation (IR): D. radiodurans R1 (wild-type) and a PprS knockdown mutant (PprSKD) that expresses ~2-fold less PprS compared to WT levels. Analysis of this RNAseq dataset demonstrated significant differential expression of several transcripts in both WT (34) and PprSKD (61) strains during recovery from IR. more...

Organism:: Deinococcus radiodurans

Type:: Expression profiling by high throughput sequencing; Other

Platform:: GPL30231
18 Samples

Download data: GFF

Series

Accession:: GSE176207

ID:: 200176207

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000649525.

Transcriptional Analysis of Deinococcus radiodurans for Novel sRNAs expression that are Differentially Expressed under Ionizing Radiation

(Submitter supplied) In this study, we identified potential sRNA candidates in D. radiodurans by a whole transcriptome deep sequencing analysis, and confirm the expression of 31 sRNAs in D. radiodurans with Northern blotting analysis and RT-PCR. A total of 8 confirmed sRNAs showed differential expression during recovery after acute ionizing radiation (15 kGy).