GEO DataSets

(Submitter supplied) The NimbleGen cattle tick custom microarray based on the BmiGI.V2 database of R. microplus ESTs was used to screen the resulting mRNA harvested from ticks treated with the tick Ubiquitin-63E 600bp dsRNA in comparison to controls. A total of 144 ESTs including TC6372 (Ubiquitin-63E) were down-regulated with 136 ESTs up-regulated following treatment. The results obtained substantiated the knockdown phenotype with ESTs identified as associated with ubiquitin proteolysis as well as oogenesis, embryogenesis, fatty acid synthesis and stress responses. more...

Organism:

Rhipicephalus microplus

Type:

Expression profiling by array

Platform:

GPL10125

8 Samples

Download data: TXT

(Submitter supplied) Babesia bovis exposed tissues: Three tissues were looked at. 1. Adult Female Gut 2. Adult Ovary 3. Larvae. In all there are 24 measurements for feature (EST), and 4 measurements per treatment for each of the 6 treatment groups. The 6 treatment groups are: Gut infected (GI), Gut control (GC), and similarly for Ovary and Larval: OI, OC, LI, LC. There are 12 chips, each with a spot replicate. more...

Organism:

Rhipicephalus microplus

Type:

Expression profiling by array

Platform:

GPL6373

24 Samples

Download data: FTR, TIFF, TXT

(Submitter supplied) Transcriptional profiling of midgut tissues isolated from Rhipicephalus microplus and Rhipicephalus decoloratus females at day 20 post infestation. This enabled the identification of transcripts that are species-specific or shared between the two tick species tested.

Organism:

Rhipicephalus microplus; Rhipicephalus decoloratus

Type:

Expression profiling by array

Platform:

GPL15231

4 Samples

Download data: GPR, TXT

(Submitter supplied) Transcriptional profiling of salivary gland, midgut and ovary tissues isolated from Rhipicephalus microplus females at day 20 post infestation. This enabled the identification of transcripts that are tissue-specific or shared among the tissues tested.

Organism:

Rhipicephalus microplus

Type:

Expression profiling by array

Platform:

GPL15231

12 Samples

Download data: GPR, TXT

(Submitter supplied) A R. microplus microarray was used to study differential gene expression in acaricide exposed larvae from an amitraz-resistant strain. The acaricide treatments were: organophosphate (OP), pyrethroid, ivermectin, and amitraz. The microarrays contained over 13,000 probes corresponding to each member of R. microplus gene index ESTs previously described (http://compbio.dfci.harvard.edu/tgi/cgi-bin/tgi/gimain.pl?gudb=b_microplus). more...

Organism:

Rhipicephalus microplus

Type:

Expression profiling by array

Platform:

GPL6373

20 Samples

Download data: TXT

(Submitter supplied) Comparative microarray analysis of Rhipicephalus (Boophilus) microplus expression profiles of larvae pre-attachment and feeding adult female stages on Bos indicus and B. taurus cattle Global analysis of gene expression changes in R. microplus during larval, pre-attachment and early adult stages of its life cycle feeding on Bos indicus and Bos taurus cattle were compared using gene expression microarray analysis. more...

Organism:

Rhipicephalus microplus

Type:

Expression profiling by array

Platform:

GPL10125

10 Samples

Download data: TXT

(Submitter supplied) Genetic factors underlying immune response to tick infestation of resistant and susceptible cattle unrevealed by omics data integration

Organism:

Bos taurus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL22316

78 Samples

Download data: TXT

(Submitter supplied) The aim of this work was to access the early immune response triggered by R. microplus larvae attachment in previously selected resistant and susceptible animals in a bovine F2 population derived from Gyr (Bos indicus) × Holstein (Bos taurus) crosses. We used microarray data both to access the changes in gene expression over the course of the first 48 hours after tick infestation as constrasting the phenotypically diferent groups.

Organism:

Bos taurus

Type:

Expression profiling by array

Platform:

GPL2112

30 Samples

Download data: CEL

(Submitter supplied) Control of complex parasites via vaccination remains challenging, with the current combination of vaccines and small drugs remaining the choice of control strategy. The development of new vaccines against complex endo- and ectoparasites remains challenging and more studies are providing evidence that multicomponent vaccines will be needed for the development of protective vaccines against parasites. more...

Organism:

Rhipicephalus microplus

Type:

Expression profiling by array

Platform:

GPL32975

6 Samples

Download data: GPR

(Submitter supplied) Transcriptional profiling of lymph nodes of three cattle breeds (Bonsmara, Brahman, Holstein-Friesian) in response to the cattle tick (Rhipicephalus microplus) larvae and adult infestation. Emphasis is placed on firstly, comparing transcriptional responses within a cattle breed, before and after infestation, and secondly, comparing differentially expressed genes common between the breeds.

Organism:

Bos taurus

Type:

Expression profiling by array

Platform:

GPL11648

27 Samples

Download data: GPR