GEO DataSets

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39 ΔcelR to D39 wild-type grown M17 medium + 0.5 % (w/v) Cellobiose (CM17).

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

3 Samples

Download data: TXT

(Submitter supplied) The human pathogen Streptococcus pneumoniae has the ability to use the carbon- and energy source cellobiose due to the presence of a cellobiose-utilizing gene cluster (cel locus) in its genome. This system is regulated by the cellobiose-dependent transcriptional activator CelR, which has been previously shown to contribute to pneumococcal virulence. To get a broader understanding of the response of S. more...

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

9 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39 wild-type grown in M17 medium+ 0.5 % (w/v) Cellobiose (CM17) to grown in M17 medium + 0.5 % (w/v) Glucose (GM17) hervasted at time point T2.

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

3 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39 wild-type grown in M17 medium+ 0.5 % (w/v) Cellobiose (CM17) to grown in M17 medium + 0.5 % (w/v) Glucose (GM17) hervasted at time point T1.

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

3 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39 ΔbguR to D39 wild-type grown in M17 medium + 0.5% glucose (GM17).

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

3 Samples

Download data: TXT

(Submitter supplied) We explored the regulatory mechanism of Leloir pathway genes in Streptococcus pneumoniae D39. Here, we demonstrate that the expression of galKT is galactose dependent. By microarray analysis and quantitative RT-PCR, we further show the role of the transcriptional regulator GalR, present upstream of galKT, as a transcriptional activator of galKT in the presence of galactose. Moreover, we predict a 19-bp regulatory site (5'-GATAGTTTAGTAAAATTTT-3' ) for the transcriptional regulator GalR in the promoter region of galK, which is also highly conserved in other streptococci. more...

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

4 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39 ΔgalR to D39 wild type grown in M17 medium+ 0.5% (w/v) galactose (GalM17).

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

2 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39 ΔgalR to D39 wild type grown in M17 medium+ 0.5% (w/v) glucose (GM17).

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

2 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39 ΔrokA to D39 wild-type grown in M17 medium + 0.5% glucose (GM17).

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

3 Samples

Download data: TXT

(Submitter supplied) In this study, we explore the impact of fucose on the transcriptome of S. pneumoniae D39. The expression of various genes and operons, including the fucose uptake PTS and utilization operon (fcs operon), was altered in the presence of fucose. By means of quantitative RT-PCR and β-galactosidase analysis, we demonstrate the role of the transcriptional regulator FcsR, present upstream of the fcs operon, as a transcriptional activator of the fcs operon. more...

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

2 Samples

Download data: TXT

(Submitter supplied) Transcriptomes of L. lactis MG1363ΔcelBΔptcCΔ0963 containing either an IS905 or a gfp integrated into llmg_1239 (pseudo_39) were compared to that of MG1363 with a Pcel (llmg_0186)up-mutation An integration of IS905 into a gene coding for a transcriptional repressor led to activation of the repressed gene cluster coding for a plant sugar utilization pathway. The strain is further characterized using DNA MicroArrays.

Organism:

Lactococcus cremoris

Type:

Expression profiling by array

Platform:

GPL23996

16 Samples

Download data: TXT

(Submitter supplied) Transcriptome Comparison of the Streptococcus pneumoniae D39 wild-type grown in CDM with 0 mM to 10mM Niacin

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL22631

2 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39 ΔnaiR to D39 wild type grown in CDM

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL22631

2 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparision of the Streptococcus pneumoniae D39 ccpA mutant to D39 wild-type grown in CDM + 0.5 % N-acetylglucosamine (NAG)

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL22631

2 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39 wild-type grown at in CDM with 0.5% Glucose to grown in CDM with 0.5 % N-acetyleglucosamine (NAG)

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

2 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39 ∆ulaR to D39 wild-type grown in M17 medium + 10mM ascorbic acid (AM17)

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

2 Samples

Download data: TXT

(Submitter supplied) Thiol peroxidase (TpxD) is one of the key enzymes used to cope with oxidative stress conditions in S. pneumoniae. Previously, we demonstrated that TpxD expression is modulated in response to H2O2 and is involved in the regulation of the psa operon. In the current study, we focus on TpxD function as a sensor and global regulator in the bacterial response to H2O2. By using microarray assays, we show that TpxD expression is necessary for the activation of bacterial global gene response to H2O2. more...

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

6 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39∆tpxD grown in THY medium till OD620=0.25 and then treated with or without 1mM H2O2 for 40mins.

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

3 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39 wild-type grown in THY medium till OD620=0.25 and then treated with or without 1mM H2O2 for 40mins.

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

3 Samples

Download data: TXT

(Submitter supplied) Streptococcus pneumoniae normally resides in the human nasopharynx in a non-disease state. In response to yet unknown triggers it can descend to the lower respiratory tract and/or invade the bloodstream. Regulation and activation of virulence genes play essential roles in this process of disease development. A putative transcriptional regulator in S. pneumoniae, MgrA, with homology to a virulence gene activator, mga, of Group A streptococcus (GAS) was previously identified as being required for development of pneumonia in a murine model. more...

Organism:

Streptococcus pneumoniae

Type:

Expression profiling by array

Platform:

GPL2712

16 Samples

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