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Links from GEO DataSets

Items: 20

1.

Exposure of bovine oocytes to elevated insulin concentration (0.1 ug/ml) during in vitro maturation changes DNA methylation pattern in Day-8-blastocysts – an epigenetic study.

(Submitter supplied) The aim was to study the potential effect of hyperinsulinemia on gene expression and differential DNA-methylation of cow embryos by adding 0.1 µg/ml (INS0.1) during in vitro oocyte maturation.
Organism:
Bos taurus
Type:
Methylation profiling by genome tiling array
Platform:
GPL18384
4 Samples
Download data: TXT
Series
Accession:
GSE97516
ID:
200097516
2.

Exposure of bovine oocytes to insulin concentration (0.1 and 10 ug/ml) during in vitro maturation changes DNA methylation pattern in Day-8-blastocysts - an epigenetic study

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Bos taurus
Type:
Methylation profiling by genome tiling array
Platform:
GPL18384
8 Samples
Download data: TXT
Series
Accession:
GSE97517
ID:
200097517
3.

Exposure of bovine oocytes to elevated insulin concentration (10 ug/ml) during in vitro maturation changes DNA methylation pattern in Day-8-blastocysts – an epigenetic study.

(Submitter supplied) The aim was to study the potential effect of hyperinsulinemia on gene expression and differential DNA-methylation of cow embryos by adding 10 µg/ml (INS10) during in vitro oocyte maturation.
Organism:
Bos taurus
Type:
Methylation profiling by genome tiling array
Platform:
GPL18384
4 Samples
Download data: TXT
Series
Accession:
GSE97515
ID:
200097515
4.

Exposure of bovine oocytes and embryos to elevated non-esterified fatty acid concentrations: integration of epigenetic and transcriptomic signatures in resultant blastocysts

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Bos taurus
Type:
Expression profiling by array; Methylation profiling by genome tiling array
Platforms:
GPL18384 GPL13226
12 Samples
Download data: TXT
Series
Accession:
GSE83768
ID:
200083768
5.

Exposure of bovine oocytes and embryos to elevated non-esterified fatty acid concentrations: integration of epigenetic and transcriptomic signatures in resultant blastocysts [gene expression]

(Submitter supplied) Metabolic stress associated with negative energy balance in high producing dairy cattle and obesity in women is a risk factor for decreased fertility. Non-esterified fatty acids (NEFA) are involved in this pathogenesis as they jeopardize oocyte and embryo development. Growing evidence indicates that maternal metabolic disorders can disturb epigenetic programming, and more specifically DNA methylation, in the offspring. more...
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL13226
4 Samples
Download data: TXT
Series
Accession:
GSE83767
ID:
200083767
6.

Exposure of bovine oocytes and embryos to elevated non-esterified fatty acid concentrations: integration of epigenetic and transcriptomic signatures in resultant blastocysts [DNA methylation]

(Submitter supplied) Metabolic stress associated with negative energy balance in high producing dairy cattle and obesity in women is a risk factor for decreased fertility. Non-esterified fatty acids (NEFA) are involved in this pathogenesis as they jeopardize oocyte and embryo development. Growing evidence indicates that maternal metabolic disorders can disturb epigenetic programming, and more specifically DNA methylation, in the offspring. more...
Organism:
Bos taurus
Type:
Methylation profiling by genome tiling array
Platform:
GPL18384
8 Samples
Download data: TXT
Series
Accession:
GSE83766
ID:
200083766
7.

Preimplantation stage-specific effect of culture environment on the DNA methylome of bovine blastocysts

(Submitter supplied) The culture conditions of the early preimplantation embryos affects the DNA methylation landscape of the resulting blastocysts.
Organism:
Bos taurus
Type:
Methylation profiling by genome tiling array
Platform:
GPL18384
16 Samples
Download data: TXT
Series
Accession:
GSE69173
ID:
200069173
8.

Gene expression analysis of in vivo originated bovine embryos fllushed out at 2- or 8-cell stages and cultured in vitro till blastocyst stage

(Submitter supplied) There is an inevitable need for combining in vitro and in vivo culture systems during specific developmental time points to facilitate a comprehensive understanding of early embryo development which would yield insights into the molecular pathways controlling early development and to improve our knowledge in regulation of embryonic development. In current study, we aimed to understand the influences of in vitro culture conditions on bovine blastocyst originated in vivo at 2- or 8-cell stagre. more...
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL13226
12 Samples
Download data: TXT
Series
Accession:
GSE111990
ID:
200111990
9.

Metabolic Stress Induces Modifications in the Epigenetic Program of Preimplantation Bovine Embryos

(Submitter supplied) we induced an energetic stress on in vitro embryos to observe the epigenetic response associated with metabolic stress. Embryos were created with slaughterhouse cows oocytes and then exposed to an elevated glucose concentration (5mM vs 0.2mM for the control embryos) for the first 3 days post fecundation and then cultivated in normal media until blastocyst stage. Blastocysts were collected from 4 different weeks of culture. more...
Organism:
Bos taurus
Type:
Methylation profiling by array
Platform:
GPL18384
4 Samples
Download data: TXT
Series
Accession:
GSE101895
ID:
200101895
10.

Bovine cumulus cells transcriptome in relation with oocyte chromatin configuration of the germinal vesicle

(Submitter supplied) Gene expression analysis in cc from COCs with different chromatin configuration (GV0-3)
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL13226
12 Samples
Download data: TXT
Series
Accession:
GSE79886
ID:
200079886
11.

The molecular characterisation of mitochondrial DNA deficient oocytes using a pig model

(Submitter supplied) Pig oocytes were stained with Brilliant cresyl blue to identify mtDNA deficient oocytes.
Organism:
Sus scrofa
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24486
40 Samples
Download data: TXT
Series
Accession:
GSE108900
ID:
200108900
12.

Differential Gene Expression Profile in Bovine Blastocysts Resulting from Hyperglycemia Exposure during Early Cleavage Stages

(Submitter supplied) IVP blastocysts exposed to hyperglycaemia during early phase of development, i.e from zygote to 8-16 cells stages. Genes expression analysis is done at day 7.5 (7 days of embryo culture).
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL13226
8 Samples
Download data: TXT
Series
Accession:
GSE33008
ID:
200033008
13.

Transcriptomic evaluation of bovine embryo quality on blastocysts obtained from peri-pubertal oocyte donors

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL13226
8 Samples
Download data: TXT
Series
Accession:
GSE85438
ID:
200085438
14.

Transcriptomic evaluation of bovine embryo quality on blastocysts obtained from peri-pubertal oocyte donors [11 mo vs 14 mo]

(Submitter supplied) Assisted reproduction technologies (ART) and high selection pressure observed in the dairy industry are leading towards the use of younger females for reproduction purpose, reducing the interval between generations. This situation might have an impact on
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL13226
4 Samples
Download data: TXT
Series
Accession:
GSE85437
ID:
200085437
15.

Transcriptomic evaluation of bovine embryo quality on blastocysts obtained from peri-pubertal oocyte donors [8 mo vs 14 mo]

(Submitter supplied) Assisted reproduction technologies (ART) and high selection pressure observed in the dairy industry are leading towards the use of younger females for reproduction purpose, reducing the interval between generations. This situation might have an impact on embryo quality, which can affect the success rate of the procedures. This study aims to document the effect of donor age on embryo quality, on transcriptomic level, in order to caracterize the effect of using young animals for reproduction purpose.
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL13226
4 Samples
Download data: TXT
Series
Accession:
GSE85436
ID:
200085436
16.

The age of the bull influences the transcriptome and epigenome of the blastocysts

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Bos taurus
Type:
Expression profiling by array; Methylation profiling by array
Platforms:
GPL18384 GPL13226
16 Samples
Download data: TXT
Series
Accession:
GSE128629
ID:
200128629
17.

Transcriptomic analysis of blastocyst according to peripubertal age of bull (12 vs 16 months)

(Submitter supplied) The transcriptome pattern in blastocyst produced by bulls at different age was investigated. Embryos were in vitro fertilized from 4 different bulls at 12 and 16 month each with matched adult cows. Genome-wide DNA methylation analysis was performed by micro array using EDMA platform.
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL13226
4 Samples
Download data: TXT
Series
Accession:
GSE128356
ID:
200128356
18.

Transcriptomic analysis of blastocyst according to peripubertal age of bull (10 vs 16 months)

(Submitter supplied) The transcriptome pattern in blastocyst produced by bulls at different age was investigated. Embryos were in vitro fertilized from 4 different bulls at 10 and 16 month each with matched adult cows. Genome-wide DNA methylation analysis was performed by micro array using EDMA platform.
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL13226
4 Samples
Download data: TXT
Series
Accession:
GSE128355
ID:
200128355
19.

DNA methylation analysis of blastocyst according to peripubertal age of bull (12 vs 16 months)

(Submitter supplied) The DNA methylation pattern in blastocyst produced by bulls at different age was investigated. Embryos were in vitro fertilized from 4 different bulls at 12 and 16 month each with matched adult cows. Genome-wide DNA methylation analysis was performed by micro array using EDMA platform.
Organism:
Bos taurus
Type:
Methylation profiling by array
Platform:
GPL18384
4 Samples
Download data: TXT
Series
Accession:
GSE128354
ID:
200128354
20.

DNA methylation analysis of blastocyst according to peripubertal age of bull (10 vs 16 months)

(Submitter supplied) The DNA methylation pattern in blastocyst produced by bulls at different age was investigated. Embryos were in vitro fertilized from 4 different bulls at 10 and 16 month each with matched adult cows. Genome-wide DNA methylation analysis was performed by micro array using EDMA platform.
Organism:
Bos taurus
Type:
Methylation profiling by array
Platform:
GPL18384
4 Samples
Download data: TXT
Series
Accession:
GSE128353
ID:
200128353
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