Similar studies for GEO DataSets (Select 200144665) - GEO DataSets

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Items: 18

Select item 2001446651.

Molecular profiling of cumulus cells and their correlation with pregnancy outcome: away from single gene marker and toward pathways analysis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Methylation profiling by genome tiling array

Platforms:: GPL13534 GPL10558
48 Samples

Download data: IDAT

Series

Accession:: GSE144665

ID:: 200144665

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001446642.

Molecular profiling of cumulus cells and their correlation with pregnancy outcome: away from single gene marker and toward pathways analysis [Methylation data]

(Submitter supplied) Worldwide the rate of infertility is on rise which put increasing pressure on assisted reproductive technology (ART) programs worldwide. Therefore it is important to increase the efficiency of ART. Toward this aim studies has been performed to find the best predictive biomarkers to choose the best germ cells for fertilization and the best embryo for transfer into uterus. However, across different studies no universal markers were found. more...

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL13534
24 Samples

Download data: IDAT, TXT

Series

Accession:: GSE144664

ID:: 200144664

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001445163.

Molecular profiling of cumulus cells and their correlation with pregnancy outcome: away from single gene marker and toward pathways analysis [Expression data]

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
24 Samples

Download data: IDAT, TXT

Series

Accession:: GSE144516

ID:: 200144516

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000372774.

Differentiating factors of cumulus cells related to quality of the human oocyte

(Submitter supplied) Single embryo transfer (SET) is the most successful way to reduce the frequency of multiple pregnancies during in vitro fertilisation. However, selecting the embryo with the highest chances of pregnancy for SET remains a difficult challenge, since morphological and kinetics criteria provide poor prediction of both developmental and implantation ability. Partly through the expression of specific genes, the oocyte-cumulus interaction helps the oocyte to acquire its developmental competence. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL4133
92 Samples

Download data

Series

Accession:: GSE37277

ID:: 200037277

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000371175.

Differentiating factors of cumulus cells related to quality of the human oocyte [CadoretPart2]

(Submitter supplied) Our aim was to identify at the level of cumulus cells any genes related to oocyte developmental competence

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL4133
36 Samples

Download data: TXT

Series

Accession:: GSE37117

ID:: 200037117

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000371166.

Differentiating factors of cumulus cells related to quality of the human oocyte [CadoretPart3]

(Submitter supplied) Our aim was to identify at the level of cumulus cells any genes related to oocyte developmental competence

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL4133
24 Samples

Download data: TXT

Series

Accession:: GSE37116

ID:: 200037116

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000371107.

Differentiating factors of cumulus cells related to quality of the human oocyte [CadoretPart1]

(Submitter supplied) Our aim was to identify at the level of cumulus cells any genes related to oocyte developmental competence

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL4133
32 Samples

Download data: TXT

Series

Accession:: GSE37110

ID:: 200037110

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000798868.

Bovine cumulus cells transcriptome in relation with oocyte chromatin configuration of the germinal vesicle

(Submitter supplied) Gene expression analysis in cc from COCs with different chromatin configuration (GV0-3)

Organism:: Bos taurus

Type:: Expression profiling by array

Platform:: GPL13226
12 Samples

Download data: TXT

Series

Accession:: GSE79886

ID:: 200079886

Select item 2000679709.

Transcriptome analysis of FSH response in bovine cumulus cells

(Submitter supplied) Study the effect of recombinant human FSH supplementation in the in vitro maturation medium for an incubation of 6 hrs on the transcriptomics of bovine cumulus cells.

Organism:: Bos taurus

Type:: Expression profiling by array

Platform:: GPL13226
6 Samples

Download data: TXT

Series

Accession:: GSE67970

ID:: 200067970

Select item 20006796910.

Transcriptome analysis of bovine cumulus cells during first 6 hrs of in vitro maturation

(Submitter supplied) Study the effect of in vitro maturation system on the transcriptomics of bovine cumulus cells during incubation of first 6 hrs.

Organism:: Bos taurus

Type:: Expression profiling by array

Platform:: GPL13226
6 Samples

Download data: TXT

Series

Accession:: GSE67969

ID:: 200067969

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20009967811.

Functional signaling and gene regulatory networks between the oocyte and the surrounding cumulus cells

(Submitter supplied) The maturation of an oocyte, the female gamete, during folliculogenesis is highly dependent on the molecular interaction with the somatic cells. Here we generated transcriptome data of single oocytes and the surrounding cumulus cells from antral follicles, and developed an analytical framework to unveil their inter-cellular communication. We identified hundreds of ligand-receptors pairs that can transduce paracrine signaling between oocyte and cumulus. more...

Organism:: Bos taurus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL19172
48 Samples

Download data: TXT

Series

Accession:: GSE99678

ID:: 200099678

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20009433812.

Effect of low dose docosahexaenoic acid (DHA) on bovine cumulus cells during in vitro maturation

(Submitter supplied) In order to decipher the pathways of DHA via cumulus cells (CC) surrounding an oocytes, microarray hybridization of cumulus cells after 4h IVM in the presence or absence of 1µM DHA was performed.

Organism:: Bos taurus

Type:: Expression profiling by array

Platform:: GPL21724
8 Samples

Download data: TXT

Series

Accession:: GSE94338

ID:: 200094338

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001081913.

Bovine adult versus prepubertal cumulus cells

(Submitter supplied) The present study was undertaken to discover molecular markers in bovine cumulus cells predictive of oocyte competence and elucidate their functional significance. Differences in RNA transcript abundance in cumulus cells harvested from oocytes of adult versus prepubertal animals (model of poor oocyte quality) were identified by microarray analysis. Four genes of interest encoding for the lysosomal cysteine proteinases cathepsin B, S, K and Z and displaying greater transcript abundance in cumulus cells surrounding oocytes harvested from prepubertal animals were chosen for further investigation. more...

Organism:: Bos taurus

Type:: Expression profiling by array

Platform:: GPL325
8 Samples

Download data: TXT

Series

Accession:: GSE10819

ID:: 200010819

Select item 20004040014.

Expression data from human cumulus cells isolated from oocytes at MI and MII stages in polycystic ovary syndrome (PCOS) patients

(Submitter supplied) Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder that is characterized by increased circulating androgen levels, anovulatory infertility, and frequently, insulin resistance and hyperinsulinemia.The abnormity of oocyte nuclear maturity is the main reason for anovulatory infertility and pregnancy loss in PCOS patients.The bidirectional exchanges between oocyte and contiguous CCs are important for oocyte competence acquisition, early embryonic development and CC expansion.Gene expression profiles of CCs has been suggested to predict embryo development and pregnancy outcome. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
6 Samples

Download data: CEL

Series

Accession:: GSE40400

ID:: 200040400

Select item 20006485815.

Gene expression analysis of pig cumulus-oocyte complexes stimulated in vitro with follicle stimulating hormone or epidermal growth factor-like peptides

(Submitter supplied) Background: The gonadotropin-induced resumption of oocyte meiosis in preovulatory follicles is preceded by expression of epidermal growth factor (EGF)-like peptides, amphiregulin (AREG) and epiregulin (EREG), in mural granulosa and cumulus cells. Both the gonadotropins and the EGF-like peptides possess the capacity to stimulate resumption of oocyte meiosis in vitro via activation of a broad signaling network in cumulus cells. more...

Organism:: Sus scrofa

Type:: Expression profiling by array

Platform:: GPL7435
9 Samples

Download data: TXT

Series

Accession:: GSE64858

ID:: 200064858

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20014903316.

Gene expression profile in human cumulus cells (CCs) during long-term in vitro culture

(Submitter supplied) In the ovarian follicle, maturation of the oocyte increases in the presence of somatic cells called cumulus cells (CCs). These cells form a direct barrier between the oocyte and external environment. Thanks to bidirectional communication, they have a direct impact on the oocyte, its quality and development potential. Understanding the genetic profile of CCs appears to be important in elucidating the physiology of oocytes. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL13667
8 Samples

Download data: CEL

Series

Accession:: GSE149033

ID:: 200149033

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20005413517.

Molecular signature in human cumulus cells related to embryonic developmental potential

(Submitter supplied) The objective of the present study was to investigate gene expression profiles of human Cumulus cells isolated from oocytes at metaphase II stage, under controlled ovarian stimulation (COS) cycle and to evaluate the relationship of embryo quality with molecular signatures in Cumulus cells. This study has been performed by microarray analysis in order to identify potential biomarkers related to oocyte developmental potential. more...

Organism:: Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platform:: GPL15314
6 Samples

Download data: TXT

Series

Accession:: GSE54135

ID:: 200054135

Select item 20004479218.

Small RNA profiling of human cumulus cells and oocytes

(Submitter supplied) Cumulus cells are biologically distinct from other follicular cells and perform specialized roles, transmitting signals within the ovary and supporting oocyte maturation during follicular development. The bi-directional communication between the oocyte and the surrounding cumulus cells is crucial for the acquisition of oocyte competence. Using Illumina/deep-sequencing technology, we dissected the small RNAome of pooled human mature MII oocytes and cumulus cells.